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    Complex: Mitochondrial respiratory chain complex IV, COX5B variant

    Macromolecular complex annotations are imported from the Complex Portal. These annotations have been derived from physical molecular interaction evidence extracted from the literature and cross-referenced in the entry, or by curator inference from information on homologs in closely related species or by inference from scientific background.


    Curated by
    IntAct
    ComplexAc
    CPX-1722
    Systematic Name
    COX1:COX2:COX3:COX4:COX5B:COX6:COX7:2xCOX8:COX9:COX12:COX13
    SGD ID
    SGD:S000218111
    Aliases
    Cytochrome C oxidase ; Cytochrome a3 ; Cytochrome c oxidase ; Ferrocytochrome c: oxygen oxidoreductase ; Mitochondrial electron transport complex IV ; NADH cytochrome c oxidase

    Complex Diagram

    This diagram displays the protein subunits (blue) of the complex and how they interact with each other. Interactions with other relevant participants such as small molecules (purple), sub-complexes (yellow), and other subunits (red) are also shown. If a participant appears in the diagram with no lines connected to it, then its specific interactions with other participants are currently unknown.


    Subunits

    This table lists all participants of the complex (proteins, small molecules, nucleic acids, etc.) and their respective stoichiometry. A brief description is also provided for each participant in the table.


    Increase the total number of rows showing on this page by using the pull-down located below the table, or use the page scroll at the table's top right to browse through its pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table.

    Subunit Description Stoichiometry

    Gene Ontology

    Gene Ontology (GO) terms that describe the function of a complex, the biological process in which it participates, or its cellular location. Click on a term for its definition and other objects annotated to that term.


      Molecular Function
    • cytochrome-c oxidase activity
      Biological Process
    • cellular respiration
    • mitochondrial electron transport, cytochrome c to oxygen
      Cellular Component
    • integral component of mitochondrial membrane
    • mitochondrial respiratory chain complex IV

    Shared Annotations

    This diagram displays Gene Ontology terms (green) and subunits (blue) that are shared between the given macromolecular complex (black) and other yeast complexes (yellow). The shared GO terms or subunits can be visualized separately using the radio button at the bottom of the graph. Note: No diagram is shown ("No shared annotations") if there are less than 2 shared annotations (either GO terms or subunits of other complexes) between this complex and any other complexes.


    References

    List of references used specifically to curate the information on this page.


    • Brzezinski P and Gennis RB (2008) Cytochrome c oxidase: exciting progress and remaining mysteries. J Bioenerg Biomembr 40(5):521-31 PMID: 18975062
      • SGD Paper
      • DOI full text
      • PMC full text
      • PubMed
    • Castello PR, et al. (2008) Oxygen-regulated isoforms of cytochrome c oxidase have differential effects on its nitric oxide production and on hypoxic signaling. Proc Natl Acad Sci U S A 105(24):8203-8 PMID: 18388202
      • SGD Paper
      • DOI full text
      • PMC full text
      • PubMed
    • Cumsky MG, et al. (1985) Two nonidentical forms of subunit V are functional in yeast cytochrome c oxidase. Proc Natl Acad Sci U S A 82(8):2235-9 PMID: 2986105
      • SGD Paper
      • DOI full text
      • PMC full text
      • PubMed

    External Identifiers


    IntEnz: 7.1.1.9
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