Alignment of GLK1/YCL040W and PDB 4IXC (chain A) Help



This page compares a protein of known structure to the Saccharomyces cerevisiae protein GLK1/YCL040W. The analysis was performed by comparing yeast protein sequences against protein sequences in The RCSB Protein Databank (PDB) using WU-BLAST.

Alignment of yeast gene GLK1/YCL040W and PDB protein 4IXC (chain A)Jump to
Structure
Alignment Details
GLK1 length = 501 aaAlignment Length = 483 aa (96.4%)P-value = 1.4e-50%Identity = 31%Similar = 21
Alignment Position

Sequence Alignment

GLK1

18

VDQICDDFEVTPEKLDELTAYFIEQMEKGLAPPKEGHTLASDKGLPMIPAFVTGSPNGTE

77






V+QI +F++ L ++ ++M++GL E H AS K M+P +V +P G+E


4IXC_(A)

7

VEQILAEFQLQAADLKKVMRRMQKEMDRGLR--LETHAAASVK---MLPTYVRSTPEGSE

61

GLK1

78

RGVLLAADLGGTNFRICSVNL-HGDH-TFSME---QMKSKIPDDLLDDENVTSDDLFGFL

132






G L+ DLGGTNFR+ V + G+ +S++ QM S IP+D + T++ LF ++


4IXC_(A)

62

VGDFLSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYS-IPEDAMTG---TAEMLFDYI

117

GLK1

133

ARRTLAFMKKYHPDELAKGKDAKPMKLGFTFSYPVDQTSLNSGTLIRWTKGFRIADTVGK

192






+ F+ K+ K + LGFTFS+PV ++ G L+ WTKGF+ + G


4IXC_(A)

118

SECISDFLDKHQMKH-------KKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGN

170

GLK1

193

DVVQLYQEQLSAQGMPMIKVVALTNDTVGTYLSHCYTSDNTDSMTSGEISEPVIGCIFGT

252






+VV L ++ + +G + VVA+ NDTV T +S CY D+ + +G I GT


4IXC_(A)

171

NVVGLLRDAIKRRGDFEMDVVAMVNDTVATMIS-CYYEDH----------QCEVGMIVGT

219

GLK1

253

GTNGCYMEEINKITKLPQELRDKLIKEGKTHMIINVEWGSFDN--ELKHLPTTKYDVVID

310






G N CYMEE+ + +L++ + M +N EWG+F + EL +YD ++D


4IXC_(A)

220

GCNACYMEEMQNV---------ELVEGDEGRMCVNTEWGAFGDSGELDEF-LLEYDRLVD

269

GLK1

311

QKLSTNPGFHLFEKRVSGMFLGEVLRNILVDLHSQGLLLQQYRSKEQLPRHLTTPFQLSS

370






+ S NPG L+EK + G ++GE++R +L+ L + LL S++ L T +


4IXC_(A)

270

ES-SANPGQQLYEKLIGGKYMGELVRLVLLRLVDENLLFHGEASEQ-----LRTRGAFET

323

GLK1

371

EVLSHIEIDDSTGLRETELSLLQSLRLPTTPTERVQIQKLVRAISRRSAYLAAVPLAAIL

430






+S +E D TG R+ ++L +L L + T+ +++ ++S R+A++ + LA ++


4IXC_(A)

324

RFVSQVESD--TGDRKQIYNILSTLGLRPSTTDCDIVRRACESVSTRAAHMCSAGLAGVI

381

GLK1

431

IKTNALNKRYHGEVEIGCDGSVVEYYPGFRSMLRHALALSPLGAEGERKVHLKIAKDGSG

490






+ + +G DGSV + +P F+ HA ++ L E + +++GSG


4IXC_(A)

382

NRMRESRSEDVMRITVGVDGSVYKLHPSFKERF-HA-SVRRLTPSCE--ITFIESEEGSG

437

GLK1

491

VGAALCALVA

500






GAAL + VA


4IXC_(A)

438

RGAALVSAVA

447

Homolog Structure
Information provided by The RCSB Protein Databank (PDB)Jump to
alignment
PDB protein4IXC (Chain A)
Crystal Structure Of Human Glucokinase In Complex With A Small Molecule Activator.
  • PDB_Info
  • Homolog SourceHomo sapiens
    External LinksSCOP
    MMDB
    CATH

    Last updated on 2016-09-15