Author: Tardiff DF

References 18 references

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Tardiff DF, et al. (2024) A Genome-Wide Analysis Indicates that Yeast Pre-mRNA Splicing Is Predominantly Posttranscriptional. Mol Cell 84(16):3165 PMID:39116873
Piotrowski JS and Tardiff DF (2019) From Yeast to Humans: Leveraging New Approaches in Yeast to Accelerate Discovery of Therapeutic Targets for Synucleinopathies. Methods Mol Biol 2049:419-444 PMID:31602625
Khurana V, et al. (2017) From Yeast to Patients: The Audacity and Vision of Susan Lindquist. Cell Syst 4(2):147-148 PMID:28231447
Khurana V, et al. (2017) Genome-Scale Networks Link Neurodegenerative Disease Genes to α-Synuclein through Specific Molecular Pathways. Cell Syst 4(2):157-170.e14 PMID:28131822
Tardiff DF, et al. (2017) Dihydropyrimidine-Thiones and Clioquinol Synergize To Target β-Amyloid Cellular Pathologies through a Metal-Dependent Mechanism. ACS Chem Neurosci 8(9):2039-2055 PMID:28628299
Khurana V, et al. (2015) Toward stem cell-based phenotypic screens for neurodegenerative diseases. Nat Rev Neurol 11(6):339-50 PMID:25986505
Matlack KE, et al. (2014) Clioquinol promotes the degradation of metal-dependent amyloid-β (Aβ) oligomers to restore endocytosis and ameliorate Aβ toxicity. Proc Natl Acad Sci U S A 111(11):4013-8 PMID:24591589
Tardiff DF, et al. (2014) From yeast to patient neurons and back again: powerful new discovery platform. Mov Disord 29(10):1231-40 PMID:25131316
Chung CY, et al. (2013) Identification and rescue of α-synuclein toxicity in Parkinson patient-derived neurons. Science 342(6161):983-7 PMID:24158904
Tardiff DF, et al. (2013) Yeast reveal a "druggable" Rsp5/Nedd4 network that ameliorates α-synuclein toxicity in neurons. Science 342(6161):979-83 PMID:24158909
Ju S, et al. (2011) A yeast model of FUS/TLS-dependent cytotoxicity. PLoS Biol 9(4):e1001052 PMID:21541368
Su LJ, et al. (2010) Compounds from an unbiased chemical screen reverse both ER-to-Golgi trafficking defects and mitochondrial dysfunction in Parkinson's disease models. Dis Model Mech 3(3-4):194-208 PMID:20038714
Macías S, et al. (2008) L30 binds the nascent RPL30 transcript to repress U2 snRNP recruitment. Mol Cell 30(6):732-42 PMID:18570876
Tardiff DF, et al. (2007) Protein characterization of Saccharomyces cerevisiae RNA polymerase II after in vivo cross-linking. Proc Natl Acad Sci U S A 104(50):19948-53 PMID:18077427
Lacadie SA, et al. (2006) In vivo commitment to yeast cotranscriptional splicing is sensitive to transcription elongation mutants. Genes Dev 20(15):2055-66 PMID:16882983
Tardiff DF and Rosbash M (2006) Arrested yeast splicing complexes indicate stepwise snRNP recruitment during in vivo spliceosome assembly. RNA 12(6):968-79 PMID:16618970
Tardiff DF, et al. (2006) A genome-wide analysis indicates that yeast pre-mRNA splicing is predominantly posttranscriptional. Mol Cell 24(6):917-29 PMID:17189193
Du H, et al. (2004) Effects of the U1C L13 mutation and temperature regulation of yeast commitment complex formation. Proc Natl Acad Sci U S A 101(41):14841-6 PMID:15465910