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  • Author: Schwacha A
  • References

Author: Schwacha A


References 16 references


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  • Sanders J, et al. (2025) An improved cytological assay for R-loop detection in Saccharomyces cerevisiae utilizing a catalytically inactive RNase H. G3 (Bethesda) 15(6) PMID:40205716
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  • Sanders J, et al. (2022) Validation of a high throughput screening assay to identify small molecules that target the eukaryotic replicative helicase. SLAS Discov 27(4):229-241 PMID:35058181
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  • Ngo M, et al. (2019) A High-Throughput Assay for DNA Replication Inhibitors Based upon Multivariate Analysis of Yeast Growth Kinetics. SLAS Discov 24(6):669-681 PMID:30802412
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  • Vijayraghavan S, et al. (2016) A Checkpoint-Related Function of the MCM Replicative Helicase Is Required to Avert Accumulation of RNA:DNA Hybrids during S-phase and Ensuing DSBs during G2/M. PLoS Genet 12(8):e1006277 PMID:27556397
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  • Bochman ML and Schwacha A (2015) DNA replication: Strand separation unravelled. Nature 524(7564):166-7 PMID:26222029
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  • Tsai FL, et al. (2015) Mcm2-7 Is an Active Player in the DNA Replication Checkpoint Signaling Cascade via Proposed Modulation of Its DNA Gate. Mol Cell Biol 35(12):2131-43 PMID:25870112
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  • Simon N, et al. (2013) Ciprofloxacin is an inhibitor of the Mcm2-7 replicative helicase. Biosci Rep 33(5) PMID:24001138
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  • Bochman ML and Schwacha A (2010) The Saccharomyces cerevisiae Mcm6/2 and Mcm5/3 ATPase active sites contribute to the function of the putative Mcm2-7 'gate'. Nucleic Acids Res 38(18):6078-88 PMID:20484375
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  • Bochman ML and Schwacha A (2008) The Mcm2-7 complex has in vitro helicase activity. Mol Cell 31(2):287-93 PMID:18657510
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  • Bochman ML, et al. (2008) Subunit organization of Mcm2-7 and the unequal role of active sites in ATP hydrolysis and viability. Mol Cell Biol 28(19):5865-73 PMID:18662997
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  • Bochman ML and Schwacha A (2007) Differences in the single-stranded DNA binding activities of MCM2-7 and MCM467: MCM2 and MCM5 define a slow ATP-dependent step. J Biol Chem 282(46):33795-33804 PMID:17895243
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  • Schwacha A and Bell SP (2001) Interactions between two catalytically distinct MCM subgroups are essential for coordinated ATP hydrolysis and DNA replication. Mol Cell 8(5):1093-104 PMID:11741544
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  • Schwacha A and Kleckner N (1997) Interhomolog bias during meiotic recombination: meiotic functions promote a highly differentiated interhomolog-only pathway. Cell 90(6):1123-35 PMID:9323140
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  • Storlazzi A, et al. (1996) Synaptonemal complex (SC) component Zip1 plays a role in meiotic recombination independent of SC polymerization along the chromosomes. Proc Natl Acad Sci U S A 93(17):9043-8 PMID:8799151
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  • Schwacha A and Kleckner N (1995) Identification of double Holliday junctions as intermediates in meiotic recombination. Cell 83(5):783-91 PMID:8521495
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  • Schwacha A and Kleckner N (1994) Identification of joint molecules that form frequently between homologs but rarely between sister chromatids during yeast meiosis. Cell 76(1):51-63 PMID:8287479
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