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  • Author: Picard D
  • References

Author: Picard D


References 24 references


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  • Bhattacharya K and Picard D (2021) The Hsp70-Hsp90 go-between Hop/Stip1/Sti1 is a proteostatic switch and may be a drug target in cancer and neurodegeneration. Cell Mol Life Sci 78(23):7257-7273 PMID:34677645
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  • Bhattacharya K, et al. (2020) The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation. Nat Commun 11(1):5975 PMID:33239621
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  • Wang T, et al. (2014) Differences in conformational dynamics between Plasmodium falciparum and human Hsp90 orthologues enable the structure-based discovery of pathogen-selective inhibitors. J Med Chem 57(6):2524-35 PMID:24580531
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  • Echeverría PC, et al. (2011) Detection of changes in gene regulatory patterns, elicited by perturbations of the Hsp90 molecular chaperone complex, by visualizing multiple experiments with an animation. BioData Min 4(1):15 PMID:21672238
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  • Wider D, et al. (2009) The complementation of yeast with human or Plasmodium falciparum Hsp90 confers differential inhibitor sensitivities. Mol Biochem Parasitol 164(2):147-52 PMID:19320098
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  • Forafonov F, et al. (2008) p23/Sba1p protects against Hsp90 inhibitors independently of its intrinsic chaperone activity. Mol Cell Biol 28(10):3446-56 PMID:18362168
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  • Picard D (2008) A stress protein interface of innate immunity. EMBO Rep 9(12):1193-5 PMID:19008919
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  • Phelps C, et al. (2006) Fungi and animals may share a common ancestor to nuclear receptors. Proc Natl Acad Sci U S A 103(18):7077-81 PMID:16636289
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  • MacLean MJ, et al. (2005) A yeast-based assay reveals a functional defect of the Q488H polymorphism in human Hsp90alpha. Biochem Biophys Res Commun 337(1):133-7 PMID:16171778
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  • MacLean M and Picard D (2003) Cdc37 goes beyond Hsp90 and kinases. Cell Stress Chaperones 8(2):114-9 PMID:14627196
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  • Abbas-Terki T, et al. (2002) The Hsp90 co-chaperones Cdc37 and Sti1 interact physically and genetically. Biol Chem 383(9):1335-42 PMID:12437126
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  • Picard D (2002) Heat-shock protein 90, a chaperone for folding and regulation. Cell Mol Life Sci 59(10):1640-8 PMID:12475174
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  • Abbas-Terki T, et al. (2001) Hsp104 interacts with Hsp90 cochaperones in respiring yeast. Mol Cell Biol 21(22):7569-75 PMID:11604493
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  • Donzé O, et al. (2001) The Hsp90 chaperone complex is both a facilitator and a repressor of the dsRNA-dependent kinase PKR. EMBO J 20(14):3771-80 PMID:11447118
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  • Abbas-Terki T, et al. (2000) The molecular chaperone Cdc37 is required for Ste11 function and pheromone-induced cell cycle arrest. FEBS Lett 467(1):111-6 PMID:10664467
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  • Abbas-Terki T and Picard D (1999) Alpha-complemented beta-galactosidase. An in vivo model substrate for the molecular chaperone heat-shock protein 90 in yeast. Eur J Biochem 266(2):517-23 PMID:10561593
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  • Donzé O and Picard D (1999) Hsp90 binds and regulates Gcn2, the ligand-inducible kinase of the alpha subunit of eukaryotic translation initiation factor 2 [corrected]. Mol Cell Biol 19(12):8422-32 PMID:10567567
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  • Louvion JF, et al. (1998) Hsp90 is required for pheromone signaling in yeast. Mol Biol Cell 9(11):3071-83 PMID:9802897
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  • Warth R, et al. (1997) Functional analysis of the yeast 40 kDa cyclophilin Cyp40 and its role for viability and steroid receptor regulation. Biol Chem 378(5):381-91 PMID:9191025
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  • Louvion JF, et al. (1996) Two eukaryote-specific regions of Hsp82 are dispensable for its viability and signal transduction functions in yeast. Proc Natl Acad Sci U S A 93(24):13937-42 PMID:8943039
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  • Palmer G, et al. (1995) Trypanosoma cruzi heat-shock protein 90 can functionally complement yeast. Mol Biochem Parasitol 70(1-2):199-202 PMID:7637703
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  • Whitelaw ML, et al. (1995) Heat shock protein hsp90 regulates dioxin receptor function in vivo. Proc Natl Acad Sci U S A 92(10):4437-41 PMID:7753824
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  • Mattioni T, et al. (1994) Regulation of protein activities by fusion to steroid binding domains. Methods Cell Biol 43 Pt A:335-52 PMID:7823870
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  • Picard D, et al. (1990) Reduced levels of hsp90 compromise steroid receptor action in vivo. Nature 348(6297):166-8 PMID:2234079
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