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  • Author: Lamb DC
  • References

Author: Lamb DC


References 30 references


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  • Riedl S, et al. (2024) Evolution of the conformational dynamics of the molecular chaperone Hsp90. Nat Commun 15(1):8627 PMID:39366960
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  • Voith von Voithenberg L, et al. (2021) Comparative analysis of the coordinated motion of Hsp70s from different organelles observed by single-molecule three-color FRET. Proc Natl Acad Sci U S A 118(33) PMID:34389669
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  • Heiss G, et al. (2019) Conformational changes and catalytic inefficiency associated with Mot1-mediated TBP-DNA dissociation. Nucleic Acids Res 47(6):2793-2806 PMID:30649478
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  • Röhl A, et al. (2015) Hsp90 regulates the dynamics of its cochaperone Sti1 and the transfer of Hsp70 between modules. Nat Commun 6:6655 PMID:25851214
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  • Gietl A, et al. (2014) Eukaryotic and archaeal TBP and TFB/TF(II)B follow different promoter DNA bending pathways. Nucleic Acids Res 42(10):6219-31 PMID:24744242
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  • Reid EL, et al. (2013) Functional and structural characterisation of a viral cytochrome b5. FEBS Lett 587(22):3633-9 PMID:24100138
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  • Sikor M, et al. (2013) Real-time observation of the conformational dynamics of mitochondrial Hsp70 by spFRET. EMBO J 32(11):1639-49 PMID:23624933
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  • Mapa K, et al. (2010) The conformational dynamics of the mitochondrial Hsp70 chaperone. Mol Cell 38(1):89-100 PMID:20385092
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  • Lange S, et al. (2008) Simultaneous transport of different localized mRNA species revealed by live-cell imaging. Traffic 9(8):1256-67 PMID:18485054
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  • Lamb DC, et al. (2006) A second FMN binding site in yeast NADPH-cytochrome P450 reductase suggests a mechanism of electron transfer by diflavin reductases. Structure 14(1):51-61 PMID:16407065
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  • Revankar SG, et al. (2004) Cloning and characterization of the lanosterol 14alpha-demethylase (ERG11) gene in Cryptococcus neoformans. Biochem Biophys Res Commun 324(2):719-28 PMID:15474487
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  • Jackson CJ, et al. (2003) Mutations in Saccharomyces cerevisiae sterol C5-desaturase conferring resistance to the CYP51 inhibitor fluconazole. Biochem Biophys Res Commun 309(4):999-1004 PMID:13679073
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  • Giaever G, et al. (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91 PMID:12140549
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  • Kelly DE, et al. (2001) Genome-wide generation of yeast gene deletion strains. Comp Funct Genomics 2(4):236-42 PMID:18628917
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  • Kelly SL, et al. (2001) An old activity in the cytochrome P450 superfamily (CYP51) and a new story of drugs and resistance. Biochem Soc Trans 29(Pt 2):122-8 PMID:11356139
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  • Lamb DC, et al. (2001) Activities and kinetic mechanisms of native and soluble NADPH-cytochrome P450 reductase. Biochem Biophys Res Commun 286(1):48-54 PMID:11485306
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  • Lamb DC, et al. (2000) Differential inhibition of human CYP3A4 and Candida albicans CYP51 with azole antifungal agents. Chem Biol Interact 125(3):165-75 PMID:10731517
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  • Kelly SL, et al. (1999) Y132H substitution in Candida albicans sterol 14alpha-demethylase confers fluconazole resistance by preventing binding to haem. FEMS Microbiol Lett 180(2):171-5 PMID:10556708
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  • Lamb DC, et al. (1999) Characteristics of the heterologously expressed human lanosterol 14alpha-demethylase (other names: P45014DM, CYP51, P45051) and inhibition of the purified human and Candida albicans CYP51 with azole antifungal agents. Yeast 15(9):755-63 PMID:10398344
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  • Lamb DC, et al. (1999) Generation of a complete, soluble, and catalytically active sterol 14 alpha-demethylase-reductase complex. Biochemistry 38(27):8733-8 PMID:10393548
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  • Lamb DC, et al. (1999) Biodiversity of the P450 catalytic cycle: yeast cytochrome b5/NADH cytochrome b5 reductase complex efficiently drives the entire sterol 14-demethylation (CYP51) reaction. FEBS Lett 462(3):283-8 PMID:10622712
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  • Lamb DC, et al. (1999) Purification, reconstitution, and inhibition of cytochrome P-450 sterol delta22-desaturase from the pathogenic fungus Candida glabrata. Antimicrob Agents Chemother 43(7):1725-8 PMID:10390230
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  • Venkateswarlu K, et al. (1998) The N-terminal membrane domain of yeast NADPH-cytochrome P450 (CYP) oxidoreductase is not required for catalytic activity in sterol biosynthesis or in reconstitution of CYP activity. J Biol Chem 273(8):4492-6 PMID:9468503
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  • Kelly SL, et al. (1997) Sterol 22-desaturase, cytochrome P45061, possesses activity in xenobiotic metabolism. FEBS Lett 412(1):233-5 PMID:9257726
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  • Kelly SL, et al. (1997) Characterization of Saccharomyces cerevisiae CYP61, sterol delta22-desaturase, and inhibition by azole antifungal agents. J Biol Chem 272(15):9986-8 PMID:9092539
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  • Lamb DC, et al. (1997) The mutation T315A in Candida albicans sterol 14alpha-demethylase causes reduced enzyme activity and fluconazole resistance through reduced affinity. J Biol Chem 272(9):5682-8 PMID:9038178
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  • Lamb DC, et al. (1997) Differential inhibition of Candida albicans CYP51 with azole antifungal stereoisomers. FEMS Microbiol Lett 149(1):25-30 PMID:9103974
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  • Kelly SL, et al. (1995) Mode of action and resistance to azole antifungals associated with the formation of 14 alpha-methylergosta-8,24(28)-dien-3 beta,6 alpha-diol. Biochem Biophys Res Commun 207(3):910-5 PMID:7864896
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  • Kelly SL, et al. (1995) Purification and reconstitution of activity of Saccharomyces cerevisiae P450 61, a sterol delta 22-desaturase. FEBS Lett 377(2):217-20 PMID:8543054
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  • Kelly SL, et al. (1993) Benzo(a)pyrene hydroxylase activity in yeast is mediated by P450 other than sterol 14 alpha-demethylase. Biochem Biophys Res Commun 197(2):428-32 PMID:8267577
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