Fu X and Hoskins AA (2025) Dynamics and evolutionary conservation of B complex protein recruitment during spliceosome activation. Nucleic Acids Res 53(4) PMID:39995036
Liu Y, et al. (2025) RNA modifications and Prp24 coordinate Lsm2-8 binding dynamics during S. cerevisiae U6 snRNP assembly. J Biol Chem 301(5):108497 PMID:40216252
Beard JP, et al. (2024) Structure-Activity Relationship Study of Splicing Modulators on Hsh155/SF3B1 through Chemical Synthesis and Yeast Genetics. ACS Med Chem Lett 15(12):2225-2230 PMID:39691513
Carrocci TJ, et al. (2024) Functional analysis of the zinc finger modules of the Saccharomyces cerevisiae splicing factor Luc7. RNA 30(8):1058-1069 PMID:38719745
Senn KA and Hoskins AA (2024) Mechanisms and regulation of spliceosome-mediated pre-mRNA splicing in Saccharomyces cerevisiae. Wiley Interdiscip Rev RNA 15(4):e1866 PMID:38972853
Lipinski KA, et al. (2023) Biochemical and genetic evidence supports Fyv6 as a second-step splicing factor in Saccharomyces cerevisiae. RNA 29(11):1792-1802 PMID:37625852
Fu X, et al. (2022) Identification of transient intermediates during spliceosome activation by single molecule fluorescence microscopy. Proc Natl Acad Sci U S A 119(48):e2206815119 PMID:36417433
Kaur H, et al. (2020) Impact of cancer-associated mutations in Hsh155/SF3b1 HEAT repeats 9-12 on pre-mRNA splicing in Saccharomyces cerevisiae. PLoS One 15(4):e0229315 PMID:32320410
Beier DH, et al. (2019) Dynamics of the DEAD-box ATPase Prp5 RecA-like domains provide a conformational switch during spliceosome assembly. Nucleic Acids Res 47(20):10842-10851 PMID:31712821
van der Feltz C, et al. (2018) Stress-induced Pseudouridylation Alters the Structural Equilibrium of Yeast U2 snRNA Stem II. J Mol Biol 430(4):524-536 PMID:29079482
Carrocci TJ, et al. (2017) SF3b1 mutations associated with myelodysplastic syndromes alter the fidelity of branchsite selection in yeast. Nucleic Acids Res 45(8):4837-4852 PMID:28062854
Cornilescu G, et al. (2016) Structural Analysis of Multi-Helical RNAs by NMR-SAXS/WAXS: Application to the U4/U6 di-snRNA. J Mol Biol 428(5 Pt A):777-789 PMID:26655855
Rodgers ML, et al. (2016) A multi-step model for facilitated unwinding of the yeast U4/U6 RNA duplex. Nucleic Acids Res 44(22):10912-10928 PMID:27484481
Rodgers ML, et al. (2015) Rapid isolation and single-molecule analysis of ribonucleoproteins from cell lysate by SNAP-SiMPull. RNA 21(5):1031-41 PMID:25805862
Anderson EG and Hoskins AA (2014) Single molecule approaches for studying spliceosome assembly and catalysis. Methods Mol Biol 1126:217-41 PMID:24549668
Crawford DJ, et al. (2013) Single-molecule colocalization FRET evidence that spliceosome activation precedes stable approach of 5' splice site and branch site. Proc Natl Acad Sci U S A 110(17):6783-8 PMID:23569281
Shcherbakova I, et al. (2013) Alternative spliceosome assembly pathways revealed by single-molecule fluorescence microscopy. Cell Rep 5(1):151-65 PMID:24075986