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  • Author: Benkovic SJ
  • References

Author: Benkovic SJ


References 15 references


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  • Kumar R, et al. (2010) Stepwise loading of yeast clamp revealed by ensemble and single-molecule studies. Proc Natl Acad Sci U S A 107(46):19736-41 PMID:21041673
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  • Zhuang Z, et al. (2008) Regulation of polymerase exchange between Poleta and Poldelta by monoubiquitination of PCNA and the movement of DNA polymerase holoenzyme. Proc Natl Acad Sci U S A 105(14):5361-6 PMID:18385374
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  • Rock FL, et al. (2007) An antifungal agent inhibits an aminoacyl-tRNA synthetase by trapping tRNA in the editing site. Science 316(5832):1759-61 PMID:17588934
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  • Zhuang Z, et al. (2006) The structure of a ring-opened proliferating cell nuclear antigen-replication factor C complex revealed by fluorescence energy transfer. Proc Natl Acad Sci U S A 103(8):2546-51 PMID:16476998
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  • Tavassoli A and Benkovic SJ (2005) Genetically selected cyclic-peptide inhibitors of AICAR transformylase homodimerization. Angew Chem Int Ed Engl 44(18):2760-2763 PMID:15830403
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  • Thoden JB, et al. (2002) PurT-encoded glycinamide ribonucleotide transformylase. Accommodation of adenosine nucleotide analogs within the active site. J Biol Chem 277(26):23898-908 PMID:11953435
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  • Greasley SE, et al. (2001) Unexpected formation of an epoxide-derived multisubstrate adduct inhibitor on the active site of GAR transformylase. Biochemistry 40(45):13538-47 PMID:11695901
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  • Thoden JB, et al. (2000) Molecular structure of Escherichia coli PurT-encoded glycinamide ribonucleotide transformylase. Biochemistry 39(30):8791-802 PMID:10913290
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  • Greasley SE, et al. (1999) New insights into inhibitor design from the crystal structure and NMR studies of Escherichia coli GAR transformylase in complex with beta-GAR and 10-formyl-5,8,10-trideazafolic acid. Biochemistry 38(51):16783-93 PMID:10606510
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  • Su Y, et al. (1998) A pH-dependent stabilization of an active site loop observed from low and high pH crystal structures of mutant monomeric glycinamide ribonucleotide transformylase at 1.8 to 1.9 A. J Mol Biol 281(3):485-99 PMID:9698564
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  • Boger DL, et al. (1997) Functionalized analogues of 5,8,10-trideazafolate: development of an enzyme-assembled tight binding inhibitor of GAR Tfase and a potential irreversible inhibitor of AICAR Tfase. Bioorg Med Chem 5(9):1839-46 PMID:9354239
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  • Boger DL, et al. (1997) 10-Formyl-5,8,10-trideazafolic acid (10-formyl-TDAF): a potent inhibitor of glycinamide ribonucleotide transformylase. Bioorg Med Chem 5(9):1817-30 PMID:9354237
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  • Klein C, et al. (1995) Towards structure-based drug design: crystal structure of a multisubstrate adduct complex of glycinamide ribonucleotide transformylase at 1.96 A resolution. J Mol Biol 249(1):153-75 PMID:7776369
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  • Schray KJ, et al. (1975) The anomeric form of D-fructose 1,6-bisphosphate used as substrate in the muscle and yeast aldolase reactions. J Biol Chem 250(13):4883-7 PMID:168195
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