Hyperactive mutation which increases affinity for tryptophan and allows cells to grow at very low tryptophan concentrations (<4ug/mL), Km value less than half of wild-type
List of references used specifically to curate the information in Overview section.
Amano K, et al. (2019) Hyperactive mutation occurs adjacent to the essential glutamate 286 for transport in the yeast tryptophan permease Tat2. Biochem Biophys Res Commun 509(4):1047-1052