Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.
112 entries for 36 phenotypesIncrease the total number of rows showing on this page using the pull-down located below the table, or use the page scroll at the table's top right to browse through the table's pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table; click on the small "i" buttons located within a cell for an annotation to view further details.
| Gene | Phenotype | Experiment Type | Mutant Information | Strain Background | Chemical | Details | Reference |
|---|---|---|---|---|---|---|---|
| PRS3 | budding index: decreased | homozygous diploid, large-scale survey | null Allele: prs3-Δ | S288C | Zettel MF, et al. (2003) PMID:12829295 | ||
| PRS3 | budding pattern: abnormal | homozygous diploid, systematic mutation set | null Allele: prs3-Δ | S288C | Details: >50% of cells exhibited random budding pattern | Ni L and Snyder M (2001) PMID:11452010 | |
| PRS3 | cell cycle progression in G1 phase: increased duration | homozygous diploid, systematic mutation set | null Allele: prs3-Δ | S288C | Details: percentage of G1 cells greater than two standard deviations (41.57%) above wild type when assayed by FACS | Hoose SA, et al. (2012) PMID:22438835 | |
| PRS3 | cell shape: abnormal | homozygous diploid, large-scale survey | null Allele: prs3-Δ | S288C | Details: round cell shape; moderate defect | Ni L and Snyder M (2001) PMID:11452010 | |
| PRS3 | cell size: decreased | systematic mutation set analysis of cell size for mutants in the systematic deletion collection | null Allele: prs3-Δ | S288C | Details: mutant is among the smallest 5% of haploid deletion strains | Jorgensen P, et al. (2002) PMID:12089449 | |
| PRS3 | cellular morphology: abnormal | classical genetics | null Allele: prs3-Δ | Other | Details: highly vacuolated, large spherical cells | Schneiter R, et al. (2000) PMID:11101685 | |
| PRS3 | chemical compound accumulation: abnormal | systematic mutation set | null Allele: prs3-Δ | S288C | alpha-amino acid | Details: Significantly altered free amino acid profile (X^2- test adjusted p < 0.01), showing 7 simultaneous amino acid changes (Z-test, adjusted p < 0.01) | Mülleder M, et al. (2016) PMID:27693354 |
| PRS3 | chemical compound accumulation: decreased | classical genetics | null Allele: prs3-Δ | Other | purine ribonucleotide | Hernando Y, et al. (1998) PMID:9829955 | |
| PRS3 | chemical compound accumulation: decreased | classical genetics | null Allele: prs3-Δ | Other | pyrimidine ribonucleotide | Hernando Y, et al. (1998) PMID:9829955 | |
| PRS3 | chemical compound accumulation: decreased | systematic mutation set | null Allele: prs3-Δ | S288C | proton | Media: external pH 5.0 | Orij R, et al. (2012) PMID:23021432 |
This diagram displays up to the top 30 positive interactions (green), negative interactions (orange), and phenotypes (blue) that are shared between the given allele (black) and other alleles (purple). The shared interactions or phenotypes can be visualized separately using the radio button at the bottom of the graph.
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