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Reference: Grela P, et al. (2012) Solution structure of the natively assembled yeast ribosomal stalk determined by small-angle X-ray scattering. Biochem J 444(2):205-9

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Abstract

The ribosomal stalk of the 60S subunit has been shown to play a crucial role in all steps of protein synthesis, but its structure and exact molecular function remain an unanswered question. In the present study, we show the low-resolution models of the solution structure of the yeast ribosomal stalk, composed of five proteins, P0-(P1-P2)(2). The model of the pentameric stalk complex determined by small-angle X-ray scattering reveals an elongated shape with a maximum length of 13 nm. The model displays three distinct lobes, which may correspond to the individual P1-P2 heterodimers anchored to the C-terminal domain of the P0 protein.

Reference Type
Journal Article
Authors
Grela P, Gajda MJ, Armache JP, Beckmann R, Krokowski D, Svergun DI, Grankowski N, Tchorzewski M
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