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Reference: Watts FZ (2007) The role of SUMO in chromosome segregation. Chromosoma 116(1):15-20

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Abstract

Chromosome segregation is an essential feature of the eukaryotic cell cycle. Efficient chromosome segregation requires the co-ordination of several cellular processes; some of which involve gross rearrangements of the overall structure of the genetic material. Recent advances in the analysis of the role of SUMO (small ubiquitin-like modifier) and in the identification of SUMO-modified targets indicate that sumoylation is likely to have several key roles in regulating chromosome segregation This mini-review summarises the recently published data concerning the role of SUMO in the processes required for efficient chromosome segregation.

Reference Type
Journal Article | Review | Research Support, Non-U.S. Gov't
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Watts FZ
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