Reference: Eckert-Boulet N and Lisby M (2010) Regulation of homologous recombination at telomeres in budding yeast. FEBS Lett 584(17):3696-702

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Abstract


Homologous recombination is suppressed at normal length telomere sequences. In contrast, telomere recombination is allowed when telomeres erode in the absence of telomerase activity or as a consequence of nucleolytic degradation or incomplete replication. Here, we review the mechanisms that contribute to regulating mitotic homologous recombination at telomeres and the role of these mechanisms in signalling short telomeres in the budding yeast Saccharomyces cerevisiae.

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Journal Article | Research Support, Non-U.S. Gov't | Review
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Eckert-Boulet N, Lisby M
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