Reference: Koehler CM, et al. (1999) How membrane proteins travel across the mitochondrial intermembrane space. Trends Biochem Sci 24(11):428-32

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Abstract


A newly discovered family of small proteins in the yeast mitochondrial intermembrane space mediates import of hydrophobic proteins from the cytoplasm into the inner membrane. Loss of one of these chaperone-like proteins from human mitochondria results in a disease that causes deafness, muscle weakness and blindness.

Reference Type
Journal Article | Research Support, Non-U.S. Gov't | Research Support, U.S. Gov't, Non-P.H.S. | Review
Authors
Koehler CM, Merchant S, Schatz G
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