Reference: Sawadogo M, et al. (1980) Similar binding site for P37 factor on yeast RNA polymerases A and B. Biochem Biophys Res Commun 96(1):258-64

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Abstract


Yeast P37 protein, which stimulates transcription of native DNA by binding to RNA polymerase B, was assayed with RNA polymerases from different origins. The factor is effective on the activity of the homologous RNA polymerases A and B. Antibodies raised against the isolated subunits of RNA polymerase A were used as a probe to investigate which of the subunits are involved in the interaction with the factor. The results indicate that P37 interacts with both RNA polymerase A and RNA polymerase B, at the level of the 23,000 daltons subunit, which is one of the three subunits comnon to both enzymes.

Reference Type
Comparative Study | Journal Article
Authors
Sawadogo M, Huet J, Fromageot P
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