Reference: Ma J and Ptashne M (1987) A new class of yeast transcriptional activators. Cell 51(1):113-9

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Abstract


We describe yeast transcriptional activators encoded by E. coli genomic DNA fragments fused to the coding sequence of the DNA-binding portion of GAL4. All of the new activating sequences that we have analyzed, like those of GAL4 and GCN4, are acidic; most of these sequences show no obvious sequence homology when compared with the identified activating regions of GAL4 and GCN4 or among themselves. We also describe a fusion protein that contains no yeast protein sequence but activates transcription in yeast.

Reference Type
Comparative Study | Journal Article | Research Support, U.S. Gov't, P.H.S.
Authors
Ma J, Ptashne M
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