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Reference: Vieillemard A, et al. (2013) The Saccharomyces cerevisiae RhoGAP Rgd1 is phosphorylated by the Aurora B like kinase Ipl1. Biochem Biophys Res Commun 433(1):1-5

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Abstract

Polarized growth of the yeast Saccharomyces cerevisiae depends on different biological processes and requires several signaling pathways. Signaling is mediated through a set of proteins, which include Rho3p and Rho4p GTPases. Although these two proteins are involved in the control of distinct aspects of polarized growth in yeast, they have a common regulator: the Rgd1 RhoGAP protein. Here we demonstrate that Rgd1p is phosphorylated by the Aurora B like kinase Ipl1 and we observe that loss of Ipl1 function leads to a new Rgd1p distribution in a small part of the cell population.

Reference Type
Journal Article | Research Support, Non-U.S. Gov't
Authors
Vieillemard A, Prouzet-Mauléon V, Hugues M, Lefebvre F, Mitteau R, Claverol S, Bonneu M, Crouzet M, Doignon F, Thoraval D
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