Reference: da Costa Morato Nery D, et al. (2008) The role of trehalose and its transporter in protection against reactive oxygen species. Biochim Biophys Acta 1780(12):1408-11

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Abstract


During menadione stress, trehalose was necessary intracellularly, but under H2O2, the sugar was required on the outside of the plasma membrane. The mechanism of protection involves minimizing the oxidative damage caused to both proteins and lipids, which would require the presence of trehalose on both sides of the lipid bilayer.

Reference Type
Journal Article | Research Support, Non-U.S. Gov't
Authors
da Costa Morato Nery D, da Silva CG, Mariani D, Fernandes PN, Pereira MD, Panek AD, Eleutherio EC
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