Reference: Rolland F, et al. (2001) Glucose-sensing mechanisms in eukaryotic cells. Trends Biochem Sci 26(5):310-7

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Abstract


Glucose not only serves as a nutrient but also exerts many hormone-like regulatory effects in a wide variety of eukaryotic cell types. Recently, interest in identifying general mechanisms and principles used to sense the presence of glucose has significantly increased and promising advances have been made: in yeast, the first proteins with an apparently specific function in glucose detection have been discovered; in plant cells, there is increasing evidence for a diverse array of glucose-induced signalling mechanisms; and in mammals, glucose-sensing phenomena have turned out to be much more widespread than just in the well-known example of pancreatic beta cells.

Reference Type
Journal Article | Research Support, Non-U.S. Gov't | Review
Authors
Rolland F, Winderickx J, Thevelein JM
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