AMA1 / YGR225W Phenotype

Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.

Summary

Non-essential gene; null mutant has a major sporulation defect; early spore wall formation is abnormal in the diploid null mutant, including the absence of beta-glucan and chitosan layers, as well as the absence of glucosamine and a reduction in diyrosine levels; homozygous diploid null mutant displays elevated levels of Clb1p, and Ssp1p and decreased activation of Smk1p after meiotic induction; overexpression results in decreased accumulation of Clb1p in diploids induced to enter meiosis; heterozygous diploid null is haploinsufficient

Annotations

A phenotype is defined as an observable (e.g., apoptosis) and a qualifier (e.g., increased). There may be more than one row with the same phenotype if that phenotype was observed in separate studies or in different conditions, strains, alleles, etc.

Shared Phenotypes

This diagram displays phenotype observables (purple squares) that are shared between the given gene (yellow circle) and other genes (gray circles) based on the number of phenotype observables shared (adjustable using the slider at the bottom).

Resources