BCK2 / YER167W Phenotype

Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.

Summary

Non-essential gene; null mutant is auxotrophic for inositol, has decreased competitive fitness on various media but increased fitness on YPD with 6% ethanol; null mutant has an increased critical cell size requirement at START, and a large cell size in both log phase and saturated culture, while overexpression results in a cell size reduction; null mutant displays increased sensitivity to several cell wall stressors (e.g. congo red, caffeine, and calcofluor white); null mutant has increased sensitivity to mating pheromone treatment while the overexpressor is more resistant; null mutant has a reduced chronological lifespan, and decreased resistance to zinc deficiency; homozygous diploid null mutant has an elevated sporulation efficiency; overexpression results in a decreased growth rate

Annotations

A phenotype is defined as an observable (e.g., apoptosis) and a qualifier (e.g., increased). There may be more than one row with the same phenotype if that phenotype was observed in separate studies or in different conditions, strains, alleles, etc.

Shared Phenotypes

This diagram displays phenotype observables (purple squares) that are shared between the given gene (yellow circle) and other genes (gray circles) based on the number of phenotype observables shared (adjustable using the slider at the bottom).

Resources