Budding Yeasts Genome Comparison

The criteria used to predict ORFs in S. paradoxus, S. mikatae and S. bayanus included a requirement for a start methionine (ATG) followed by an uninterrupted reading frame encoding at least 49 amino acids (ie the first or only exon is at least 150 nucleotides).

There are many known S. cerevisiae ORFs that would not meet this requirement. As a consequence, any S. cerevisiae ORF with a first (or only) exon smaller than 150 nucleotides was identified as an ORF of "no similarity" simply because the set of predicted S. paradoxus, S. mikatae and S. bayanus ORFs did not include potential orthologs for these unusually small proteins.

The following table lists 59 S. cerevisiae ORFs that were excluded from the "Budding Yeasts Genome Comparison" due to their small size. Orthology could not be predicted for these ORFs.

Gene	nucleotides in 1st (or only) exon
LSM2	54
RPL19B	2
YBR191W-A	75
PMP1	123
YCR038W-A	126
YDL012C	45
YDL114W-A	114
RPL41B	78
RPL35B	3
YDL159W-A	132
RPL41A	78
RPL35A	3
YDL247W-A	75
DYN2	25
RPL27B	31
RPL37B	7
YDR535C	48
PMP2	132
YER053C-A	114
RPL34A	37
YER074W-A	95
RPL22B	12
RPL30	3
OST5	21
RPS23A	65
QCR9	3
VMA10	3
RPL42B	4
RPS24B	3
YJL052C-A	120
YJL127W-A	117
RPS21B	24
RPL39	6
NCE101	32
YJR079W	143
RPL14A	129
RPS21A	24
RPL22A	12
YLR149C-A	87
RPL37A	7
YLR202C	62
YML007C-A	111
RPL6A	15
RPS16A	24
RPS10B	52
MFA2	117
RPL18B	112
YOR008W-B	102
RPS30B	3
RPS10A	52
YOR302W	78
YOR314W-A	111
YOR318C	4
RPS9A	7
TAF14	9
RPL33A	19
RPL7B	11
RPL43A	2
RPS23B	65