This page displays data from Segal et al and was kindly provided to SGD by Eran Segal.

Module 2 (15 Genes) - Stress Analysis
Jump to: Significant GO annotations | Significant Motif Binding Sites.
Predicted Regulatory Module
The control program is a set of gene products predicted to regulate the cluster of genes below. The prediction is based on the relationship between the expression of the regulator and the expression of genes in the cluster as described in Segal et al. In several instances, there is direct experimental evidence to corroborate the predicted function of the regulators. In this view, the regulators (circled gene products) are in a hierarchy according to their effects on gene expression in the experiments directly below them.


Jump to: Predicted Control Program | Significant Motif Binding Sites.
 
Significant GO Annotations
This table lists, in order of significance, all GO annotations enriched in this cluster at a pvalue below 0.01. For each significant GO annotation, this table displays the following statistics: the number of genes in the cluster with the annotation (Hits), the percentage of genes in the cluster with the annotation (Hits (%)), the total number of genes in the entire dataset with the annotation (Total) and the pvalue of the annotation enrichment.
GO Term Ontology Hits Hits (%) Total Pvalue
peroxidase activity Molecular Function 5 33.33 6 2.98488e-11
oxidoreductase activity\, acting on peroxide as acceptor Molecular Function 5 33.33 7 1.04026e-10
cell redox homeostasis Biological Process 5 33.33 8 2.76221e-10
regulation of redox homeostasis Biological Process 5 33.33 8 2.76221e-10
oxidoreductase activity Molecular Function 9 60 117 5.15082e-09
response to oxidative stress Biological Process 5 33.33 17 2.93698e-08
response to stress Biological Process 8 53.33 167 2.14807e-06
cell homeostasis Biological Process 5 33.33 46 5.74116e-06
homeostasis Biological Process 5 33.33 49 7.88328e-06
enzyme activity Molecular Function 9 60 644 0.00616908


Jump to: Predicted Control Program | Significant GO Annotations.
 
Significant Motif Binding Sites
This table lists, in order of significance, all motif binding sites enriched in this cluster at a pvalue below 0.01. For each significant motif binding site, the following statistics are displayed: the number of genes in the cluster with the binding site in their promoter (Hits), the percentage of genes with the binding site in their promoter (Hits (%)), the total number of genes in the dataset with the binding site in their promoter (Total) and the pvalue of the binding site enrichment. To view the sequence logo for each motif, click on the motif name.
Motif Source Consensus Hits Hits (%) Total Pvalue
STRE_01 TRANSFAC TCAGGGGG 12 80 881 0.000932143
GAL4_C TRANSFAC TCGGAGCACTGTCCTCCGAACG 7 46.66 374 0.00443708
STRE_B TRANSFAC CAGGGGC 12 80 819 0.000442802