This page displays data from Segal et al and was kindly provided to SGD by Eran Segal.

Module 9 (30 Genes) - Stress Analysis

Jump to: Significant GO annotations | Significant Motif Binding Sites.

Predicted Regulatory Module

The control program is a set of gene products predicted to regulate the cluster of genes below. The prediction is based on the relationship between the expression of the regulator and the expression of genes in the cluster as described in Segal et al. In several instances, there is direct experimental evidence to corroborate the predicted function of the regulators. In this view, the regulators (circled gene products) are in a hierarchy according to their effects on gene expression in the experiments directly below them.

Jump to: Predicted Control Program | Significant Motif Binding Sites.

Significant GO Annotations
This table lists, in order of significance, all GO annotations enriched in this cluster at a pvalue below 0.01. For each significant GO annotation, this table displays the following statistics: the number of genes in the cluster with the annotation (Hits), the percentage of genes in the cluster with the annotation (Hits (%)), the total number of genes in the entire dataset with the annotation (Total) and the pvalue of the annotation enrichment.
GO Term	Ontology	Hits	Hits (%)	Total	Pvalue
cell proliferation	Biological Process	14	46.66	156	9.50769e-10
cell growth and/or maintenance	Biological Process	17	56.66	447	3.55062e-06
cellular process	Biological Process	16	53.33	428	1.07421e-05
cell cycle	Biological Process	8	26.66	98	1.67393e-05
cytokinesis	Biological Process	7	23.33	73	2.17251e-05
regulation of cell cycle	Biological Process	5	16.66	37	7.32247e-05
site of polarized growth (sensu Saccharomyces)	Cellular Component	5	16.66	43	0.000151507
site of polarized growth	Cellular Component	5	16.66	43	0.000151507
site of polarized growth (sensu Fungi)	Cellular Component	5	16.66	43	0.000151507
regulation of CDK activity	Biological Process	3	10	10	0.000206678
bud neck	Cellular Component	4	13.33	25	0.000214494
axial budding	Biological Process	3	10	12	0.000370232
cyclin-dependent protein kinase\, regulator activity	Molecular Function	3	10	14	0.000598526
M phase of mitotic cell cycle	Biological Process	4	13.33	36	0.000882578
mitotic cell cycle	Biological Process	4	13.33	37	0.000978463
mitosis	Biological Process	4	13.33	43	0.00170856
protein kinase regulator activity	Molecular Function	3	10	22	0.00230748
nuclear division	Biological Process	4	13.33	50	0.00294542
shmoo	Cellular Component	3	10	24	0.00296288
M phase	Biological Process	4	13.33	54	0.00386515
kinase regulator activity	Molecular Function	3	10	27	0.00413469
shmoo tip	Cellular Component	3	10	27	0.00413469
asexual reproduction	Biological Process	3	10	28	0.00457715
budding	Biological Process	3	10	30	0.00554163
small GTPase regulatory/interacting protein activity	Molecular Function	3	10	31	0.00606413
cytokinesis\, site selection	Biological Process	3	10	35	0.00842626

Jump to: Predicted Control Program | Significant GO Annotations.

Significant Motif Binding Sites
This table lists, in order of significance, all motif binding sites enriched in this cluster at a pvalue below 0.01. For each significant motif binding site, the following statistics are displayed: the number of genes in the cluster with the binding site in their promoter (Hits), the percentage of genes with the binding site in their promoter (Hits (%)), the total number of genes in the dataset with the binding site in their promoter (Total) and the pvalue of the binding site enrichment. To view the sequence logo for each motif, click on the motif name.
Motif	Source	Consensus	Hits	Hits (%)	Total	Pvalue
MCM1_01	TRANSFAC	TTTCCTAATCAGGTAA	10	33.33	183	6.45719e-05
MAT1MC_02	TRANSFAC	TCCATTGTTT	9	30	256	0.00320072