This page displays data from Segal et al and was kindly provided to SGD by Eran Segal.

Module 12 (64 Genes) - Stress Analysis

Jump to: Significant GO annotations | Significant Motif Binding Sites.

Predicted Regulatory Module

The control program is a set of gene products predicted to regulate the cluster of genes below. The prediction is based on the relationship between the expression of the regulator and the expression of genes in the cluster as described in Segal et al. In several instances, there is direct experimental evidence to corroborate the predicted function of the regulators. In this view, the regulators (circled gene products) are in a hierarchy according to their effects on gene expression in the experiments directly below them.

Jump to: Predicted Control Program | Significant Motif Binding Sites.

Significant GO Annotations
This table lists, in order of significance, all GO annotations enriched in this cluster at a pvalue below 0.01. For each significant GO annotation, this table displays the following statistics: the number of genes in the cluster with the annotation (Hits), the percentage of genes in the cluster with the annotation (Hits (%)), the total number of genes in the entire dataset with the annotation (Total) and the pvalue of the annotation enrichment.
GO Term	Ontology	Hits	Hits (%)	Total	Pvalue
energy pathways	Biological Process	8	12.5	46	1.97497e-05
energy derivation by oxidation of organic compounds	Biological Process	8	12.5	49	3.17092e-05
sulfur amino acid metabolism	Biological Process	6	9.37	32	0.000150124
amino acid biosynthesis	Biological Process	5	7.81	23	0.000269621
tricarboxylic acid cycle	Biological Process	4	6.25	14	0.000383995
amino acid metabolism	Biological Process	9	14.06	89	0.000419818
sulfur metabolism	Biological Process	7	10.93	54	0.00043367
carbohydrate metabolism	Biological Process	8	12.5	72	0.000476791
main pathways of carbohydrate metabolism	Biological Process	5	7.81	27	0.00058381
glutamate biosynthesis	Biological Process	3	4.68	7	0.000603785
glutamine family amino acid biosynthesis	Biological Process	3	4.68	7	0.000603785
enzyme activity	Molecular Function	28	43.75	644	0.00174842
TCA cycle enzyme complex	Cellular Component	4	6.25	28	0.00545512
mitochondrial matrix	Cellular Component	4	6.25	28	0.00545512
transferase activity	Molecular Function	11	17.18	185	0.00631934
extracellular	Cellular Component	13	20.31	243	0.00711799
sulfur amino acid biosynthesis	Biological Process	3	4.68	16	0.00761969
glutamine family amino acid metabolism	Biological Process	3	4.68	17	0.00901118
mitochondrion	Cellular Component	9	14.06	143	0.00919132

Jump to: Predicted Control Program | Significant GO Annotations.

Significant Motif Binding Sites
This table lists, in order of significance, all motif binding sites enriched in this cluster at a pvalue below 0.01. For each significant motif binding site, the following statistics are displayed: the number of genes in the cluster with the binding site in their promoter (Hits), the percentage of genes with the binding site in their promoter (Hits (%)), the total number of genes in the dataset with the binding site in their promoter (Total) and the pvalue of the binding site enrichment. To view the sequence logo for each motif, click on the motif name.
Motif	Source	Consensus	Hits	Hits (%)	Total	Pvalue
ADR1_01	TRANSFAC	CGGGGT	39	60.93	1052	0.0061309
STRE_01	TRANSFAC	TCAGGGGG	50	78.12	843	2.91959e-11
STRE_B	TRANSFAC	CAGGGGC	47	73.43	784	2.65909e-10
CAT8_Q6	TRANSFAC	CCATTCGTCC	28	43.75	632	0.00250616