This page displays data from Segal et al and was kindly provided to SGD by Eran Segal.

Module 16 (59 Genes) - Stress Analysis

Jump to: Significant GO annotations | Significant Motif Binding Sites.

Predicted Regulatory Module

The control program is a set of gene products predicted to regulate the cluster of genes below. The prediction is based on the relationship between the expression of the regulator and the expression of genes in the cluster as described in Segal et al. In several instances, there is direct experimental evidence to corroborate the predicted function of the regulators. In this view, the regulators (circled gene products) are in a hierarchy according to their effects on gene expression in the experiments directly below them.

Jump to: Predicted Control Program | Significant Motif Binding Sites.

Significant GO Annotations
This table lists, in order of significance, all GO annotations enriched in this cluster at a pvalue below 0.01. For each significant GO annotation, this table displays the following statistics: the number of genes in the cluster with the annotation (Hits), the percentage of genes in the cluster with the annotation (Hits (%)), the total number of genes in the entire dataset with the annotation (Total) and the pvalue of the annotation enrichment.
GO Term	Ontology	Hits	Hits (%)	Total	Pvalue
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	Biological Process	21	35.59	366	7.22192e-05
nucleus	Cellular Component	22	37.28	400	8.64335e-05
RNA binding activity	Molecular Function	8	13.55	61	8.67452e-05
transcription	Biological Process	13	22.03	178	0.000235494
transcription\, DNA-dependent	Biological Process	12	20.33	161	0.000348198
nucleic acid binding activity	Molecular Function	10	16.94	118	0.000417918
nuclease activity	Molecular Function	5	8.47	36	0.00152025
transcription from Pol I promoter	Biological Process	5	8.47	42	0.00297769
chromatin silencing at telomere	Biological Process	3	5.08	14	0.0041732
rRNA processing	Biological Process	4	6.77	29	0.00466458
RNA metabolism	Biological Process	6	10.16	68	0.00499396
mRNA catabolism	Biological Process	3	5.08	16	0.00611675
RNA catabolism	Biological Process	3	5.08	17	0.00724965
nucleoplasm	Cellular Component	6	10.16	75	0.00779494
acetyltransferase activity	Molecular Function	3	5.08	18	0.00849121
ribonuclease activity	Molecular Function	3	5.08	19	0.00984169

Jump to: Predicted Control Program | Significant GO Annotations.

Significant Motif Binding Sites
This table lists, in order of significance, all motif binding sites enriched in this cluster at a pvalue below 0.01. For each significant motif binding site, the following statistics are displayed: the number of genes in the cluster with the binding site in their promoter (Hits), the percentage of genes with the binding site in their promoter (Hits (%)), the total number of genes in the dataset with the binding site in their promoter (Total) and the pvalue of the binding site enrichment. To view the sequence logo for each motif, click on the motif name.
Motif	Source	Consensus	Hits	Hits (%)	Total	Pvalue