This page displays data from Segal et al and was kindly provided to SGD by Eran Segal.

Module 20 (64 Genes) - Stress Analysis
Jump to: Significant GO annotations | Significant Motif Binding Sites.
Predicted Regulatory Module
The control program is a set of gene products predicted to regulate the cluster of genes below. The prediction is based on the relationship between the expression of the regulator and the expression of genes in the cluster as described in Segal et al. In several instances, there is direct experimental evidence to corroborate the predicted function of the regulators. In this view, the regulators (circled gene products) are in a hierarchy according to their effects on gene expression in the experiments directly below them.


Jump to: Predicted Control Program | Significant Motif Binding Sites.
 
Significant GO Annotations
This table lists, in order of significance, all GO annotations enriched in this cluster at a pvalue below 0.01. For each significant GO annotation, this table displays the following statistics: the number of genes in the cluster with the annotation (Hits), the percentage of genes in the cluster with the annotation (Hits (%)), the total number of genes in the entire dataset with the annotation (Total) and the pvalue of the annotation enrichment.
GO Term Ontology Hits Hits (%) Total Pvalue
metabolism Biological Process 46 71.87 1130 4.94967e-05
protein metabolism Biological Process 23 35.93 409 0.000158758
Golgi apparatus Cellular Component 5 7.81 25 0.000404445
ergosterol biosynthesis Biological Process 4 6.25 16 0.000662836
protein secretion Biological Process 8 12.5 78 0.000804579
chromatin modeling Biological Process 6 9.37 45 0.000970501
secretory pathway Biological Process 8 12.5 81 0.00102423
steroid biosynthesis Biological Process 4 6.25 19 0.00130571
sterol biosynthesis Biological Process 4 6.25 19 0.00130571
intra-Golgi transport Biological Process 3 4.68 9 0.00137475
sterol metabolism Biological Process 4 6.25 20 0.00159021
ER to Golgi transport Biological Process 5 7.81 34 0.00168089
transcription from Pol II promoter Biological Process 7 10.93 69 0.00181137
steroid metabolism Biological Process 4 6.25 21 0.0019139
nucleoplasm Cellular Component 7 10.93 75 0.00286339
alcohol metabolism Biological Process 4 6.25 24 0.00314253
intracellular Cellular Component 22 34.37 490 0.00412802
GTPase activator activity Molecular Function 3 4.68 13 0.00421226
intracellular protein transport Biological Process 9 14.06 128 0.00478954
physiological processes Biological Process 52 81.25 1589 0.0056152
binding activity Molecular Function 8 12.5 108 0.00569525
protein targeting Biological Process 8 12.5 113 0.00729655
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism Biological Process 17 26.56 366 0.00833081


Jump to: Predicted Control Program | Significant GO Annotations.
 
Significant Motif Binding Sites
This table lists, in order of significance, all motif binding sites enriched in this cluster at a pvalue below 0.01. For each significant motif binding site, the following statistics are displayed: the number of genes in the cluster with the binding site in their promoter (Hits), the percentage of genes with the binding site in their promoter (Hits (%)), the total number of genes in the dataset with the binding site in their promoter (Total) and the pvalue of the binding site enrichment. To view the sequence logo for each motif, click on the motif name.
Motif Source Consensus Hits Hits (%) Total Pvalue
TAF_Q6 TRANSFAC CGTCCGAAACGACCA 18 28.12 374 0.00749678