This page displays data from Segal et al and was kindly provided to SGD by Eran Segal.

Module 30 (48 Genes) - Stress Analysis
Jump to: Significant GO annotations | Significant Motif Binding Sites.
Predicted Regulatory Module
The control program is a set of gene products predicted to regulate the cluster of genes below. The prediction is based on the relationship between the expression of the regulator and the expression of genes in the cluster as described in Segal et al. In several instances, there is direct experimental evidence to corroborate the predicted function of the regulators. In this view, the regulators (circled gene products) are in a hierarchy according to their effects on gene expression in the experiments directly below them.


Jump to: Predicted Control Program | Significant Motif Binding Sites.
 
Significant GO Annotations
This table lists, in order of significance, all GO annotations enriched in this cluster at a pvalue below 0.01. For each significant GO annotation, this table displays the following statistics: the number of genes in the cluster with the annotation (Hits), the percentage of genes in the cluster with the annotation (Hits (%)), the total number of genes in the entire dataset with the annotation (Total) and the pvalue of the annotation enrichment.
GO Term Ontology Hits Hits (%) Total Pvalue
nuclear organization and biogenesis Biological Process 6 12.5 19 1.11792e-06
protein-nucleus import Biological Process 6 12.5 21 2.15615e-06
nuclear pore Cellular Component 6 12.5 22 2.91136e-06
rRNA-nucleus export Biological Process 5 10.41 13 3.16208e-06
mRNA-binding (hnRNP) protein-nucleus import Biological Process 5 10.41 14 4.82848e-06
nuclear pore organization and biogenesis Biological Process 5 10.41 14 4.82848e-06
protein-nucleus export Biological Process 5 10.41 17 1.41167e-05
nucleocytoplasmic transport Biological Process 6 12.5 29 1.6319e-05
mRNA-nucleus export Biological Process 5 10.41 20 3.34526e-05
nuclear membrane Cellular Component 6 12.5 33 3.53734e-05
snRNA-nucleus export Biological Process 4 8.33 12 6.47618e-05
NLS-bearing substrate-nucleus import Biological Process 4 8.33 12 6.47618e-05
ribosomal protein-nucleus import Biological Process 4 8.33 12 6.47618e-05
snRNP protein-nucleus import Biological Process 4 8.33 12 6.47618e-05
RNA-nucleus export Biological Process 5 10.41 23 6.86642e-05
tRNA-nucleus export Biological Process 4 8.33 13 9.17881e-05
RNA localization Biological Process 5 10.41 28 0.000182715
protein targeting Biological Process 9 18.75 113 0.00027835
cellular process Biological Process 18 37.5 428 0.000748623
structural molecule activity Molecular Function 6 12.5 58 0.000817094
cell organization and biogenesis Biological Process 9 18.75 132 0.000846358
nucleic acid binding activity Molecular Function 8 16.66 118 0.0017166
intracellular protein transport Biological Process 8 16.66 128 0.00280007
cell growth and/or maintenance Biological Process 17 35.41 447 0.0031235
mRNA catabolism Biological Process 3 6.25 16 0.00346352
RNA catabolism Biological Process 3 6.25 17 0.00412479
protein metabolism Biological Process 15 31.25 409 0.00756524
cell Cellular Component 32 66.66 1181 0.00803607
ribonucleoprotein complex Cellular Component 8 16.66 160 0.00973806


Jump to: Predicted Control Program | Significant GO Annotations.
 
Significant Motif Binding Sites
This table lists, in order of significance, all motif binding sites enriched in this cluster at a pvalue below 0.01. For each significant motif binding site, the following statistics are displayed: the number of genes in the cluster with the binding site in their promoter (Hits), the percentage of genes with the binding site in their promoter (Hits (%)), the total number of genes in the dataset with the binding site in their promoter (Total) and the pvalue of the binding site enrichment. To view the sequence logo for each motif, click on the motif name.
Motif Source Consensus Hits Hits (%) Total Pvalue