This page displays data from Segal et al and was kindly provided to SGD by Eran Segal.

Module 39 (31 Genes) - Stress Analysis

Jump to: Significant GO annotations | Significant Motif Binding Sites.

Predicted Regulatory Module

The control program is a set of gene products predicted to regulate the cluster of genes below. The prediction is based on the relationship between the expression of the regulator and the expression of genes in the cluster as described in Segal et al. In several instances, there is direct experimental evidence to corroborate the predicted function of the regulators. In this view, the regulators (circled gene products) are in a hierarchy according to their effects on gene expression in the experiments directly below them.

Jump to: Predicted Control Program | Significant Motif Binding Sites.

Significant GO Annotations
This table lists, in order of significance, all GO annotations enriched in this cluster at a pvalue below 0.01. For each significant GO annotation, this table displays the following statistics: the number of genes in the cluster with the annotation (Hits), the percentage of genes in the cluster with the annotation (Hits (%)), the total number of genes in the entire dataset with the annotation (Total) and the pvalue of the annotation enrichment.
GO Term	Ontology	Hits	Hits (%)	Total	Pvalue
proteasome endopeptidase activity	Molecular Function	7	22.58	12	2.5041e-11
threonine endopeptidase activity	Molecular Function	7	22.58	12	2.5041e-11
26S proteasome	Cellular Component	7	22.58	16	3.47101e-10
ubiquitin-dependent protein catabolism	Biological Process	7	22.58	30	5.34416e-08
cytosol	Cellular Component	10	32.25	98	1.95442e-07
peptidase activity	Molecular Function	7	22.58	38	3.04865e-07
protein modification	Biological Process	10	32.25	115	8.86839e-07
19S proteasome regulatory particle	Cellular Component	4	12.90	8	1.64513e-06
20S core proteasome complex	Cellular Component	3	9.67	4	8.17185e-06
cytoplasm	Cellular Component	16	51.61	437	2.38898e-05
cytoskeletal protein binding activity	Molecular Function	4	12.90	16	3.89864e-05
actin cytoskeleton	Cellular Component	4	12.90	24	0.000207402
protein metabolism	Biological Process	14	45.16	409	0.000213481
protein binding activity	Molecular Function	5	16.12	64	0.00110875
intracellular	Cellular Component	14	45.16	490	0.00134607
actin filament organization	Biological Process	3	9.67	18	0.00140896
cytoskeleton	Cellular Component	4	12.90	40	0.00147952
cytoskeleton organization and biogenesis	Biological Process	3	9.67	28	0.00501307
hydrolase activity	Molecular Function	8	25.80	230	0.00587688

Jump to: Predicted Control Program | Significant GO Annotations.

Significant Motif Binding Sites
This table lists, in order of significance, all motif binding sites enriched in this cluster at a pvalue below 0.01. For each significant motif binding site, the following statistics are displayed: the number of genes in the cluster with the binding site in their promoter (Hits), the percentage of genes with the binding site in their promoter (Hits (%)), the total number of genes in the dataset with the binding site in their promoter (Total) and the pvalue of the binding site enrichment. To view the sequence logo for each motif, click on the motif name.
Motif	Source	Consensus	Hits	Hits (%)	Total	Pvalue
HSF_03	TRANSFAC	AGAACAGAACGTTCT	7	22.58	165	0.00448197