This page displays data from Segal et al. and was kindly provided to SGD by Eran Segal.

Module 3 (69 Genes) - Cell Cycle Analysis
Jump to: Significant GO annotations | Significant Motif Binding Sites.
Predicted Regulatory Module
The control program is a set of gene products predicted to regulate the cluster of genes below. The prediction is based on the relationship between the expression of the regulator and the expression of genes in the cluster as described in Segal et al. In several instances, there is direct experimental evidence to corroborate the predicted function of the regulators. In this view, the regulators (circled gene products) are in a hierarchy according to their effects on gene expression in the experiments directly below them.


Jump to: Predicted Control Program | Significant Motif Binding Sites.
 
Significant GO Annotations
This table lists, in order of significance, all GO annotations enriched in this cluster at a pvalue below 0.01. For each significant GO annotation, this table displays the following statistics: the number of genes in the cluster with the annotation (Hits), the percentage of genes in the cluster with the annotation (Hits (%)), the total number of genes in the entire dataset with the annotation (Total) and the pvalue of the annotation enrichment.
GO Term Ontology Hits Hits (%) Total Pvalue
response to abiotic stimulus Biological Process 25 36.23 181 6.85398e-06
response to external stimulus Biological Process 26 37.68 200 1.31758e-05
physiological processes Biological Process 63 91.30 858 8.88126e-05
response to pheromone Biological Process 20 28.98 150 0.000123112
chemosensory perception Biological Process 20 28.98 150 0.000123112
sensory perception Biological Process 20 28.98 151 0.00013511
perception of external stimulus Biological Process 20 28.98 152 0.000148122
perception of chemical substance Biological Process 20 28.98 152 0.000148122
perception of abiotic stimulus Biological Process 20 28.98 153 0.000162219
endomembrane system Cellular Component 28 40.57 271 0.000386871
unlocalized Cellular Component 8 11.59 34 0.000425361
regulation of transcription\, DNA-dependent Biological Process 22 31.88 194 0.000559836
protein phosphatase type 2A activity Molecular Function 4 5.79 8 0.000613187
viral genome expression Biological Process 4 5.79 8 0.000613187
nucleus Cellular Component 31 44.92 323 0.000626515
basal lamina Cellular Component 15 21.73 112 0.000918408
extracellular matrix Cellular Component 15 21.73 112 0.000918408
basement membrane Cellular Component 15 21.73 112 0.000918408
membrane Cellular Component 34 49.27 378 0.00101532
regulation of transcription from Pol II promoter Biological Process 17 24.63 139 0.00114058
sporulation (sensu Saccharomyces) Biological Process 6 8.69 23 0.00131006
sporulation (sensu Fungi) Biological Process 6 8.69 23 0.00131006
response to stress Biological Process 18 26.08 154 0.00135395
sporulation Biological Process 6 8.69 24 0.00165105
cytoplasm Cellular Component 21 30.43 200 0.00200553
cell ion homeostasis Biological Process 5 7.24 18 0.00251266
protein serine/threonine phosphatase activity Molecular Function 6 8.69 26 0.00252283
transcription regulator activity Molecular Function 22 31.88 222 0.00315805
cell adhesion Biological Process 3 4.34 6 0.00328068
protein serine/threonine phosphatase complex Cellular Component 4 5.79 12 0.00344536
extracellular Cellular Component 15 21.73 130 0.00383292
cell homeostasis Biological Process 5 7.24 20 0.0040566
regulation of transcription by pheromones Biological Process 11 15.94 83 0.00472891
RNA polymerase II transcription factor activity Molecular Function 9 13.04 64 0.00703972
protein phosphatase activity Molecular Function 5 7.24 23 0.00741685
bud growth Biological Process 4 5.79 15 0.00799154
actin filament organization Biological Process 4 5.79 15 0.00799154
transcription co-activator activity Molecular Function 3 4.34 8 0.00817583
protein tyrosine phosphatase activity Molecular Function 3 4.34 8 0.00817583
transcription Biological Process 15 21.73 143 0.00864644
enzyme regulator activity Molecular Function 7 10.14 44 0.00889852


Jump to: Predicted Control Program | Significant GO Annotations.
 
Significant Motif Binding Sites
This table lists, in order of significance, all motif binding sites enriched in this cluster at a pvalue below 0.01. For each significant motif binding site, the following statistics are displayed: the number of genes in the cluster with the binding site in their promoter (Hits), the percentage of genes with the binding site in their promoter (Hits (%)), the total number of genes in the dataset with the binding site in their promoter (Total) and the pvalue of the binding site enrichment. To view the sequence logo for each motif, click on the motif name.
Motif Source Consensus Hits Hits (%) Total Pvalue
GCN4_C TRANSFAC CAATGACTCA 16 23.18 114 0.00150268