This page displays data from Segal et al. and was kindly provided to SGD by Eran Segal.

Module 12 (80 Genes) - Cell Cycle Analysis

Jump to: Significant GO annotations | Significant Motif Binding Sites.

Predicted Regulatory Module

The control program is a set of gene products predicted to regulate the cluster of genes below. The prediction is based on the relationship between the expression of the regulator and the expression of genes in the cluster as described in Segal et al. In several instances, there is direct experimental evidence to corroborate the predicted function of the regulators. In this view, the regulators (circled gene products) are in a hierarchy according to their effects on gene expression in the experiments directly below them.

Jump to: Predicted Control Program | Significant Motif Binding Sites.

Significant GO Annotations
This table lists, in order of significance, all GO annotations enriched in this cluster at a pvalue below 0.01. For each significant GO annotation, this table displays the following statistics: the number of genes in the cluster with the annotation (Hits), the percentage of genes in the cluster with the annotation (Hits (%)), the total number of genes in the entire dataset with the annotation (Total) and the pvalue of the annotation enrichment.
GO Term	Ontology	Hits	Hits (%)	Total	Pvalue
response to pheromone	Biological Process	22	27.5	150	0.000130173
chemosensory perception	Biological Process	22	27.5	150	0.000130173
sensory perception	Biological Process	22	27.5	151	0.000143734
perception of external stimulus	Biological Process	22	27.5	152	0.000158521
perception of chemical substance	Biological Process	22	27.5	152	0.000158521
perception of abiotic stimulus	Biological Process	22	27.5	153	0.000174625
response to external stimulus	Biological Process	26	32.5	200	0.000216571
response to abiotic stimulus	Biological Process	23	28.75	181	0.000740417
regulation of transcription\, DNA-dependent	Biological Process	24	30	194	0.000820027
regulation of transcription from Pol II promoter by pheromones	Biological Process	9	11.25	44	0.00156306
regulation of transcription by pheromones	Biological Process	13	16.25	83	0.00189601
transcription regulator activity	Molecular Function	25	31.25	222	0.00235179
protein kinase activity	Molecular Function	8	10	40	0.00324111
nucleus	Cellular Component	32	40	323	0.00420378
regulation of transcription from Pol II promoter	Biological Process	17	21.25	139	0.00531884
signal transducer activity	Molecular Function	15	18.75	122	0.00808702
physiological processes	Biological Process	67	83.75	858	0.00823098
macromolecule catabolism	Biological Process	5	6.25	21	0.00915426

Jump to: Predicted Control Program | Significant GO Annotations.

Significant Motif Binding Sites
This table lists, in order of significance, all motif binding sites enriched in this cluster at a pvalue below 0.01. For each significant motif binding site, the following statistics are displayed: the number of genes in the cluster with the binding site in their promoter (Hits), the percentage of genes with the binding site in their promoter (Hits (%)), the total number of genes in the dataset with the binding site in their promoter (Total) and the pvalue of the binding site enrichment. To view the sequence logo for each motif, click on the motif name.
Motif	Source	Consensus	Hits	Hits (%)	Total	Pvalue