This page displays data from Segal et al. and was kindly provided to SGD by Eran Segal.

Module 13 (42 Genes) - Cell Cycle Analysis
Jump to: Significant GO annotations | Significant Motif Binding Sites.
Predicted Regulatory Module
The control program is a set of gene products predicted to regulate the cluster of genes below. The prediction is based on the relationship between the expression of the regulator and the expression of genes in the cluster as described in Segal et al. In several instances, there is direct experimental evidence to corroborate the predicted function of the regulators. In this view, the regulators (circled gene products) are in a hierarchy according to their effects on gene expression in the experiments directly below them.


Jump to: Predicted Control Program | Significant Motif Binding Sites.
 
Significant GO Annotations
This table lists, in order of significance, all GO annotations enriched in this cluster at a pvalue below 0.01. For each significant GO annotation, this table displays the following statistics: the number of genes in the cluster with the annotation (Hits), the percentage of genes in the cluster with the annotation (Hits (%)), the total number of genes in the entire dataset with the annotation (Total) and the pvalue of the annotation enrichment.
GO Term Ontology Hits Hits (%) Total Pvalue
DNA repair Biological Process 9 21.42 35 1.31577e-06
DNA metabolism Biological Process 13 30.95 84 2.08994e-06
DNA replication Biological Process 9 21.42 48 2.12743e-05
DNA strand elongation Biological Process 5 11.90 16 0.000141901
DNA dependent DNA replication Biological Process 7 16.66 38 0.000219506
replication fork Cellular Component 5 11.90 18 0.000260819
S phase of mitotic cell cycle Biological Process 7 16.66 41 0.000355931
recombinational repair Biological Process 4 9.52 11 0.00037323
double-strand break repair Biological Process 4 9.52 11 0.00037323
mitotic recombination Biological Process 4 9.52 13 0.000756618
DNA replication and chromosome cycle Biological Process 7 16.66 47 0.00082433
intracellular Cellular Component 17 40.47 237 0.0011886
chromatin remodeling complex Cellular Component 3 7.14 7 0.0013074
double-strand break repair via synthesis-dependent strand annealing Biological Process 3 7.14 8 0.00202187
double-strand break repair via homologous recombination Biological Process 3 7.14 8 0.00202187
nucleotidyltransferase activity Molecular Function 4 9.52 17 0.002204
viral genome replication Biological Process 4 9.52 17 0.002204
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism Biological Process 17 40.47 254 0.00252537
DNA-directed DNA polymerase activity Molecular Function 3 7.14 9 0.00293128
lagging strand elongation Biological Process 3 7.14 10 0.00404724
mismatch repair Biological Process 3 7.14 12 0.00693044
nucleotide-excision repair Biological Process 3 7.14 12 0.00693044
maintenance of fidelity during DNA dependent DNA replication Biological Process 3 7.14 12 0.00693044
pyrimidine-dimer repair Biological Process 3 7.14 12 0.00693044
nuclear division Biological Process 7 16.66 70 0.007545
M phase of mitotic cell cycle Biological Process 6 14.28 55 0.00887199
mitotic cell cycle Biological Process 6 14.28 56 0.00961667
cell proliferation Biological Process 13 30.95 198 0.00998374


Jump to: Predicted Control Program | Significant GO Annotations.
 
Significant Motif Binding Sites
This table lists, in order of significance, all motif binding sites enriched in this cluster at a pvalue below 0.01. For each significant motif binding site, the following statistics are displayed: the number of genes in the cluster with the binding site in their promoter (Hits), the percentage of genes with the binding site in their promoter (Hits (%)), the total number of genes in the dataset with the binding site in their promoter (Total) and the pvalue of the binding site enrichment. To view the sequence logo for each motif, click on the motif name.
Motif Source Consensus Hits Hits (%) Total Pvalue
STUAP_01 TRANSFAC CATCGCGTCC 27 64.28 305 6.64569e-07