This page displays data from Segal et al. and was kindly provided to SGD by Eran Segal.

Module 21 (26 Genes) - Cell Cycle Analysis

Jump to: Significant GO annotations | Significant Motif Binding Sites.

Predicted Regulatory Module

The control program is a set of gene products predicted to regulate the cluster of genes below. The prediction is based on the relationship between the expression of the regulator and the expression of genes in the cluster as described in Segal et al. In several instances, there is direct experimental evidence to corroborate the predicted function of the regulators. In this view, the regulators (circled gene products) are in a hierarchy according to their effects on gene expression in the experiments directly below them.

Jump to: Predicted Control Program | Significant Motif Binding Sites.

Significant GO Annotations
This table lists, in order of significance, all GO annotations enriched in this cluster at a pvalue below 0.01. For each significant GO annotation, this table displays the following statistics: the number of genes in the cluster with the annotation (Hits), the percentage of genes in the cluster with the annotation (Hits (%)), the total number of genes in the entire dataset with the annotation (Total) and the pvalue of the annotation enrichment.
GO Term	Ontology	Hits	Hits (%)	Total	Pvalue
ATP dependent DNA helicase activity	Molecular Function	5	19.23	6	2.11234e-08
pre-replicative complex formation and maintenance	Biological Process	5	19.23	8	1.90117e-07
adenosinetriphosphatase activity	Molecular Function	6	23.07	15	2.75976e-07
DNA unwinding	Biological Process	5	19.23	9	4.20053e-07
chromatin binding activity	Molecular Function	5	19.23	10	8.2495e-07
ATP binding activity	Molecular Function	6	23.07	18	9.71449e-07
DNA dependent adenosinetriphosphatase activity	Molecular Function	5	19.23	11	1.4851e-06
ATPase activity	Molecular Function	6	23.07	22	3.64065e-06
DNA replication initiation	Biological Process	5	19.23	14	6.0925e-06
hydrolase activity\, acting on acid anhydrides\, in phosphorus-containing anhydrides	Molecular Function	6	23.07	28	1.65436e-05
hydrolase activity\, acting on acid anhydrides	Molecular Function	6	23.07	29	2.04949e-05
DNA dependent DNA replication	Biological Process	6	23.07	38	0.000101571
S phase of mitotic cell cycle	Biological Process	6	23.07	41	0.000156831
nucleoplasm	Cellular Component	7	26.92	59	0.000157294
DNA replication and chromosome cycle	Biological Process	6	23.07	47	0.000336451
DNA replication	Biological Process	6	23.07	48	0.000377685
binding activity	Molecular Function	6	23.07	49	0.000422734
nucleic acid binding activity	Molecular Function	6	23.07	52	0.000583143
DNA binding activity	Molecular Function	7	26.92	92	0.00227045
DNA metabolism	Biological Process	6	23.07	84	0.00649122

Jump to: Predicted Control Program | Significant GO Annotations.

Significant Motif Binding Sites
This table lists, in order of significance, all motif binding sites enriched in this cluster at a pvalue below 0.01. For each significant motif binding site, the following statistics are displayed: the number of genes in the cluster with the binding site in their promoter (Hits), the percentage of genes with the binding site in their promoter (Hits (%)), the total number of genes in the dataset with the binding site in their promoter (Total) and the pvalue of the binding site enrichment. To view the sequence logo for each motif, click on the motif name.
Motif	Source	Consensus	Hits	Hits (%)	Total	Pvalue
MCM1_01	TRANSFAC	TTTCCTAATCAGGTAA	15	57.69	136	4.57547e-08