This page displays data from Segal et al. and was kindly provided to SGD by Eran Segal.

Module 26 (74 Genes) - Cell Cycle Analysis
Jump to: Significant GO annotations | Significant Motif Binding Sites.
Predicted Regulatory Module
The control program is a set of gene products predicted to regulate the cluster of genes below. The prediction is based on the relationship between the expression of the regulator and the expression of genes in the cluster as described in Segal et al. In several instances, there is direct experimental evidence to corroborate the predicted function of the regulators. In this view, the regulators (circled gene products) are in a hierarchy according to their effects on gene expression in the experiments directly below them.


Jump to: Predicted Control Program | Significant Motif Binding Sites.
 
Significant GO Annotations
This table lists, in order of significance, all GO annotations enriched in this cluster at a pvalue below 0.01. For each significant GO annotation, this table displays the following statistics: the number of genes in the cluster with the annotation (Hits), the percentage of genes in the cluster with the annotation (Hits (%)), the total number of genes in the entire dataset with the annotation (Total) and the pvalue of the annotation enrichment.
GO Term Ontology Hits Hits (%) Total Pvalue
nucleus Cellular Component 38 51.35 323 4.19037e-06
endomembrane system Cellular Component 32 43.24 271 3.71772e-05
cell communication Biological Process 13 17.56 71 0.000204223
transcription regulator activity Molecular Function 26 35.13 222 0.000306087
response to external stimulus Biological Process 24 32.43 200 0.000386454
response to abiotic stimulus Biological Process 22 29.72 181 0.000595336
signal transduction Biological Process 13 17.56 80 0.000662183
response to pheromone Biological Process 19 25.67 150 0.000900477
chemosensory perception Biological Process 19 25.67 150 0.000900477
regulation of transcription from Pol II promoter Biological Process 18 24.32 139 0.00096409
sensory perception Biological Process 19 25.67 151 0.00097471
membrane Cellular Component 36 48.64 378 0.000976916
protein binding activity Molecular Function 7 9.45 28 0.00102124
perception of chemical substance Biological Process 19 25.67 152 0.00105401
perception of external stimulus Biological Process 19 25.67 152 0.00105401
macromolecule catabolism Biological Process 6 8.10 21 0.00113721
perception of abiotic stimulus Biological Process 19 25.67 153 0.00113863
regulation of transcription\, DNA-dependent Biological Process 22 29.72 194 0.00148535
ubiquitin-protein ligase activity Molecular Function 4 5.40 10 0.00212393
acid-D-amino acid ligase activity Molecular Function 4 5.40 10 0.00212393
regulation of transcription by pheromones Biological Process 12 16.21 83 0.0028426
intracellular signaling cascade Biological Process 8 10.81 43 0.00316949
establishment of cell polarity (sensu Saccharomyces) Biological Process 6 8.10 26 0.00355746
small GTPase mediated signal transduction Biological Process 7 9.45 35 0.00379854
ubiquitin ligase complex Cellular Component 4 5.40 12 0.00442163
ligase activity\, forming carbon-nitrogen bonds Molecular Function 4 5.40 12 0.00442163
nuclear ubiquitin ligase complex Cellular Component 4 5.40 12 0.00442163
protein modification Biological Process 9 12.16 58 0.00589761
ubiquitin-dependent protein catabolism Biological Process 4 5.40 13 0.00600172
carrier activity Molecular Function 6 8.10 29 0.00610931
3'-5' exoribonuclease activity Molecular Function 3 4.05 7 0.00658076
mRNA catabolism Biological Process 3 4.05 7 0.00658076
RNA catabolism Biological Process 3 4.05 7 0.00658076
mRNA catabolism\, deadenylation-dependent Biological Process 3 4.05 7 0.00658076
CCR4-NOT complex Cellular Component 3 4.05 7 0.00658076
transcription initiation from Pol II promoter Biological Process 4 5.40 14 0.00789536
transcription initiation Biological Process 4 5.40 14 0.00789536
metabolism Biological Process 41 55.40 505 0.00848646
protein metabolism Biological Process 15 20.27 134 0.00910263
transcription cofactor activity Molecular Function 5 6.75 23 0.00979064
protein phosphatase activity Molecular Function 5 6.75 23 0.00979064
exoribonuclease activity Molecular Function 3 4.05 8 0.00988806
exoribonuclease activity\, producing 5'-phosphomonoesters Molecular Function 3 4.05 8 0.00988806
mRNA metabolism Biological Process 3 4.05 8 0.00988806


Jump to: Predicted Control Program | Significant GO Annotations.
 
Significant Motif Binding Sites
This table lists, in order of significance, all motif binding sites enriched in this cluster at a pvalue below 0.01. For each significant motif binding site, the following statistics are displayed: the number of genes in the cluster with the binding site in their promoter (Hits), the percentage of genes with the binding site in their promoter (Hits (%)), the total number of genes in the dataset with the binding site in their promoter (Total) and the pvalue of the binding site enrichment. To view the sequence logo for each motif, click on the motif name.
Motif Source Consensus Hits Hits (%) Total Pvalue