| 1 | Modeling the potential for complex genetic interactions: Actin displays a rich spectrum of complex haploinsufficiencies. Brian Haarer1, Susan Viggiano1, Olga Troyanskaya2, David C. Amberg1. 1) Dept Biochemistry & Molec Biol, SUNY Upstate Medical Univ, Syracuse, NY; 2) Department of Computer Science, Princeton University, Princeton, NJ. |
| 2 | Goal-directed evidence integration for predicting biological networks in yeast. Chad Myers, Olga Troyanskaya. Lewis Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ. |
| 3 | A global and dynamic view of networks that regulate the transcriptional response to DNA damage. Craig Mak1, Trey Ideker2. 1) Biology, UCSD, La Jolla, CA; 2) Bioengineering, UCSD, La Jolla, CA. |
| 4 | Evaluating quantitative measures of epistasis for predicting functional relationships. Ramamurthy Mani1, Robert P. St Onge2, Julia Oh2, Michael Proctor2, Eula Fung2, Ronald W. Davis2, Corey Nislow2, Guri N. Giaever1, Frederick P. Roth1. 1) Harvard Medical School, Boston, MA, 02115; 2) The Department of Biochemistry, Stanford University, Stanford, California, USA, 94305. |
| 5 | Metabolomic analysis of respiring yeast by comprehensive GCXGC-TOFMS: the missing link between a dynamic transcriptome and growth on non-fermentable carbon sources. Kenneth M. Dombek1, Rachel E. Mohler2, Robert E. Synovec2, Elton T. Young1. 1) Department of Biochemistry, University of Washington, Seattle, WA; 2) Department of Chemistry, University of Washington, Seattle, WA. |
| 6 | Global Landscape of Protein Complexes in the Yeast Saccharomyces cerevisiae. Nevan Krogan1,2, Gerard Cagney1,3, Haiyuan Yu4, Gouqing Zhong1,2, Xinghua Guo1,2, Alexandr Ignatchenko1,2, Peter Wong1, Shuye Pu5, Gabe Musso1,2, Aaron P. Tikuisis1, Thanuja Punna1, José M. Peregrín-Alvarez5, Dawn P. Richards6, James Vlasblom5, Samuel Wu5, John Parkinson5, Marc Gerstein4, Shoshana J. Wodak5, Jack F. Greenblatt1,2, Andrew Emili1,2. 1) Banting & Best Department of Medical Research, Terrence Donnelly Centre for Cellular and Biomolecular Research (DCCBR), University of Toronto, Toronto, ON, CANADA; 2) Department of Medical Genetics and Microbiology, University of Toronto, Toronto, ON, CANADA; 3) Conway Institute, University College Dublin, Belfield, Dublin, IRELAND; 4) Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT; 5) Hospital for Sick Children, Toronto, ON, CANADA; 6) Affinium Pharmaceuticals, Toronto, ON, CANADA. |
| 7 | Nuclear translocation of the Hog1 MAP kinase is not necessary for resistance to hyperosmotic stress. Patrick Westfall, Jesse Patterson, Jeremy Thorner. Dept Mol & Cellular Biol, Univ California, Berkeley, Berkeley, CA. |
| 8 | Adaptor protein Ste50p links the Ste11p MEKK to the HOG pathway through plasma membrane association. Cunle Wu1, Gregor Jansen2, Jianchun Zhang1, David Y. Thomas2, Malcolm Whiteway1,3. 1) Eukaryotic Genetics Group, Biotechnology Research Institute, Montreal, QC, Canada; 2) Department of Biochemistry, McGill University, Montreal, QC, Canada; 3) Department of Biology, McGill University, Montreal QC, Canada. |
| 9 | Crosstalk between HOG1 and SLT2 MAPK pathways is necessary for Saccharomyces cerevisiae cell survival under cell wall stress. C. Bermejo, E. Rodríguez, R. García, P. Arias, A. B. Sanz, N. Blanco, S. Díez, J. M. Rodríguez-Peña, C. Nombela, J. Arroyo. Dpto. Microbiología II. Fac. Farmacia. Universidad Complutense de Madrid 28040. Spain. |
| 10 | Functional Analysis of Mad3 in the Spindle Assembly Checkpoint in Budding Yeast. Janet Burton, Mark Solomon. Molecular Biophys. & Biochem., Yale University, New Haven, CT. |
| 11 | Kar9p and Bim1p interact with Smt3p and the machinery for sumoylation. Nida Meednu1, Harold Hoops2, Leah Pogorzala1, Elaine Sia1, Rita Miller1. 1) Dept Biol, Univ Rochester, Rochester, NY; 2) Dept Biol, State University of New York, Geneseo, NY. |
| 12 | The Role of Mps2 and Mps3 at the Budding Yeast Spindle Pole Body Half-Bridge. Sue Jaspersen. Stowers Institute for Medical Research, Kansas City, MO. |
| 13 | Following the steps of nuclear envelope fusion in budding yeast. Patricia Melloy1, Shu Shen1, Erin White2, Mark Winey2, J. Richard McIntosh2, Mark Rose1. 1) Molecular Biology, Princeton University, Princeton, NJ; 2) MCD Biology, University of Colorado at Boulder, CO. |
| 14 | The phospholipase D, Spo14p, and t-SNARE, Sso1p, are required for vesicle fusion in prospore membrane formation. Hideki Nakanishi1, Masayo Morishita2, Cindi L. Schwartz3, Alison Coluccio1, JoAnne Engebrecht2, Aaron M. Neiman1. 1) Biochemistry and Cell Biology, SUNY Stony Brook, Stony Brook, NY; 2) Section of Molecular and Cellular Biology, UC Davis, Davis, CA; 3) Boulder Laboratory for 3D Electron Microscopy of Cells, University of Colorado, Boulder, CO. |
| 15 | Trs130 is required for the specificity switch of a dual-Ypt/Rab GEF. Nava Segev1, Nadya Morozova1, Yongheng Liang1, Andrei tokarev1, Shu Chen1, Vicki Sciora2, Scott Emr2. 1) Biological Sci, Lab Molec Biol, Univ Illinois, Chicago, Chicago, IL; 2) Callular and Molecular Medicine, Univ California, San Diego, CA. |
| 16 | Experimental Evolution Of High-Copy Ty1 Strains. Lisa Z. Scheifele1,2, Maitreya J. Dunham3, Sarah J. Wheelan1,2, Jef D. Boeke1,2. 1) Molecular Biology and Genetics; 2) The High Throughput Biology Center, The Johns Hopkins University School of Medicine, Baltimore, MD; 3) Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ. |
| 17 | Genome-wide analysis of polyploidy in yeast: scaling effects, chromosome segregation and genome stability. Zuzana Storchova1, Kendra Burbank2, Amanda Breneman1, Jessica Cande1, Joshua Dunn1, David Pellman1. 1) Dept Ped Oncol, Dana-Farber Cancer Inst, Boston, MA., USA; 2) Dept of Physics, Harvard University, Boston, MA, USA. |
| 18 | Anti-fungal drug Resistance is associated with aneuploidy and isochromosome formation in Candida albicans. Anna Selmecki, Anja Forche, Judith Berman. Dept Genetics, Cell Biol & Dev, Univ Minnesota, Minneapolis, MN. |
| 19 | Multiple homeostatic mechanisms regulate the activity of the Pho85 cyclin Pcl5. Tsvia Gildor, Sharon Aviram, Revital Shemer, Daniel Kornitzer. Dept Molec Microbiol, Fac Med, Technion-IIT, Haifa, Israel. |
| 20 | The identification of the GTPase activating protein Rga2 as a target of the cyclin-dependent kinase Pho85. Richelle Sopko1,3, Dongqing Huang1, Brenda Andrews1,2,3. 1) Terrence Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON, Canada; 2) Banting and Best Department of Medical Research, University of Toronto, Toronto ON, Canada; 3) Department of Medical Genetics and Microbiology, University of Toronto, Toronto ON, Canada. |
| 21 | Phosphoregulation of Cbk1 integrates RAM network control of gene expression and morphogenesis. Jaclyn Jansen, Margaret Barry, Eric Weiss. Dept BMBCB, Northwestern Univ, Evanston, IL. |
| 22 | AgSwe1p regulates mitosis in response to morphogenesis and nutrients in multinucleated A. gossyppii cells. Amy Gladfelter1, Hanspeter Helfer2. 1) Department of Biology, Dartmouth College, Hanover, NH; 2) Molecular Microbiology, Biozentrum-University of Basel, Basel, Switzerland. |
| 23 | Fus3 activity dynamics control periodic gene expression and morphogenesis. Zoe Hilioti1, Walid Sabbagh, Jr.2, Saurabh Paliwal1, Adriel Bergmann1, Marcus Goncalves1, Lee Bardwell2,3, Andre Levchenko1. 1) Biomedical Engineering, Johns Hopkins University, Baltimore, MD; 2) Developmental and Cell Biology, University of California, Irvine, CA; 3) Institute for Genomics and Bioinformatics, University of California, Irvine, CA. |
| 24 | Two “redundant” inhibitors of the MAPK-responsive transcription factor Ste12 differentially modulate noise during yeast pheromone signaling. Emma McCullagh, Anupama Seshan, Hana El-Samad, Hiten Madhani. Biochemistry and Biophysics, UCSF, San Francisco, CA. |
| 25 | A high-resolution map of transcription in the yeast genome. Lior David1, Wolfgang Huber2, Marina Granovskaia3, Joern Toedling2, Curtis J. Palm1, Lee Bofkin2, Ted Jones1, Ronald W. Davis1, Lars M. Steinmetz1,3. 1) Dept of Biochemistry, Stanford Genome Technology Ctr, Palo Alto, CA; 2) European Bioinformatics Institute, European Molecular Biology aboratory, Cambridge CB10 1SD, England; 3) European Molecular Biology Laboratory, 69117 Heidelberg, Germany. |
| 26 | Evolution of a rapid glucose sensing circuit: A role for paralogs. Jeff Sabina, Mark Johnston. Dept. of Genetics, Washington University in St. Louis, St. Louis, MO. |
| 27 | Functional specialization in the yeast ribosome revealed by high-resolution phenomics. Jonathan L.S. Esguerra, Jonas Warringer, Luciano Fernandez-Ricaud, Anders Blomberg. CMB-Microbiology, Lundberg Lab, Göteborg University, Göteborg, Sweden. |
| 28 | Defining the yeast transcriptome. Albert Lee, Michal Ronen, Katja Schwartz, Gavin Sherlock. Department of Genetics, Stanford University, Stanford, CA. |
| 29 | Redefining Nodes and Edges: Relating 3D Structures to Yeast Protein Networks Provides Insights into their Evolution. Philip M. Kim1, Long Lu1, Yu Xia1, Mark Gerstein1,2. 1) Department of Molecular Biophysics & Biochemistry, Yale University, New Haven, CT; 2) Department of Computer Science, Yale University, New Haven, CT. |
| 30 | Chemogenomic profiling reveals functional relationships in yeast. Maureen Hillenmeyer1,2, Russ Altman2,3, Ronald Davis1,3, Corey Nislow1, Guri Giaever1. 1) Stanford Genome Technology Center; 2) Program in Biomedical Informatics; 3) Department of Genetics, Stanford University. |
| 31 | Novel cell-cycle regulation of the mutagenic translesion DNA polymerase Rev1. Laurie S Waters, Graham C. Waters. Massachusetts Institute of Technology, Cambridge, MA. |
| 32 | Efficient double-strand break repair is required to prevent expansion and breakage of structure-forming CAG/CTG repeats and promote survival of cells with expanded repeats. Rangapriya Sundararajan, Rachel Zunder, Catherine H. Freudenreich. Department of Biology, Tufts University, Medford, MA. |
| 33 | Mec1 and Ku70 activity controls initiation of homologous recombination. Jacqueline H. Barlow1, Michael Lisby2, Rodney J. Rothstein1. 1) Genetics and Development, Columbia University, New York, NY; 2) Department of Genetics, Institute of Molecular Biology and Physiology, University of Copenhagen, DK-1353 Copenhagen, Denmark. |
| 34 | The telomerase accessory protein, Est1p, is a cell cycle regulated activator of telomere-bound telomerase in vivo. Creighton T. Tuzon, Virginia A. Zakian. Princeton University, Molecular Biology Department, Princeton, NJ USA. |
| 35 | Cell Cycle Control of DNA Replication. Richard Morreale, Brian Green, Muluye Liku, Joachim J. Li. Univ. California, San Francisco, San Francisco, CA. |
| 36 | Genome-wide hierarchy of replication origin usage in Saccharomyces cerevisiae. Justin Donato, Shau Chee Chung, Bik-Kwoon Tye. Dept Molec Biol & Genetics, Cornell Univ, Ithaca, NY. |
| 37 | Silent chromatin and the cohesion of sister chromatids. Marc R. Gartenberg, Ching-Shyi Wu, Rudra Dubey. Pharmacology Dept, Robert Wood Johnson Med School, Piscataway, NJ. |
| 38 | Smc3, a component of the cohesin complex, forms a cylinder around the mitotic spindle. Leocadia V. Paliulis, Kerry Bloom. Department of Biology, University of North Carolina, Chapel Hill, NC. |
| 39 | A novel role for the centromere specific histone 3 variant at a non-centromeric locus: Assembly of the yeast plasmid partitioning complex at an impostor centromere. Makkuni Jayaram, Sujata Hajra, Ghosh Santanu, Hong Cui. Molecular Genetics & Microbiol, Univ Texas, Austin, Austin, TX. |
| 40 | Quantitative Study of Epigenetic Gene Expression in Live Cells. Eugenia Xu, Karl Zawadzki, James Broach. Department of Molecular Biology, Princeton University, Princeton, NJ. |
| 41 | Gene looping is dependent upon the general transcription factor IIB. Badri N. Singh, Michael Hampsey. Division of Nucleic Acids Research, Department of Biochemistry, University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School, Piscataway, New Jersey 08854, USA. |
| 42 | On establishment, containment and evolution of silencing in Saccharomyces. Jasper Rine, Joshua Babiarz, Jennifer Gallagher, Jeff Halley, Erin Osborne, Bilge Ozydin, Leonid Teytelman, Oliver Zill. Dept Molecular & Cell Biol, Univ California, Berkeley, CA. |
| 43 | A genetic screening that evaluates the upper limit gene copy number in S. cerevisiae; application to the system level analysis of cell division cycle related genes. Hisao Moriya, Yuki Shimizu-Yoshida, Hiroaki Kitano. The Systems Biology Institute, Shibuya-ku, Japan. |
| 44 | Transcriptional regulation at Start by the G1 cyclin Cln3. Hong-yin Wang, Ying Cai, Bruce Futcher. Microbiology, Stony Brook University, Stony Brook, NY. |
| 45 | Hcm1 is an S phase-specific hub in the transcriptional circuitry of the cell cycle that is required for high fidelity chromosome transmission. Tata Pramila1, Wei Wu1, 2, Shawna Miles1, William Stafford Noble2, Linda Breeden1. 1) Basic Sci Division, Fred Hutchinson Cancer Res Ctr, Seattle, WA; 2) Dept. Genome sciences, University of Washington, Seattle, WA. |
| 46 | Association of pH-sensing Machinery with Endosomal Compartments. Jacob Boysen1,2, Aaron Mitchell1,2. 1) Department of Microbiology, Columbia University, New York, NY; 2) Integrated Program in Cellular, Molecular and Biophysical Studies, Columbia University, New York, NY. |
| 47 | Slm1 and Slm2 are novel substrates of the calcineurin phosphatase required for heat stress-induced endocytosis of the yeast uracil permease. Geert Bultynck1, Victoria L. Heath1, Alia P. Majeed1, Jean-Marc Galan2, Rosine Haguenauer-Tsapis2, Martha S. Cyert1. 1) Dept Biological Sci, Stanford Univ, Stanford, CA; 2) Institut Jacques Monod-CNRS, Universitie Paris VII, 2 place Jussieu, 75005 Paris, France. |
| 48 | Signal transduction in yeast via PAQR receptors. Brian Kupchak1, Lisa Regalla1, Nancy Villa1, Christina Appin1, Anna Vagstad1, Charlene Wolford2, Ashley Cowart2, Yusuf Hannun2, Thomas Lyons1. 1) Chemistry, University of Florida, Gainesville, FL; 2) Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston. |
| 49 | Yeast Oxysterol-Binding Proteins affect Cdc42p- and Rho1p-mediated cell polarization. Christopher Beh1, Gabriel Alfaro1, Shubha Dighe2, Keith Kozminski2. 1) Department of Molecular Biology & Biochemistry, Simon Fraser University, Burnaby, BC, Canada; 2) Departments of Biology & Cell Biology, University of Virginia, Charottesville, VA. |
| 50 | Outer nuclear membrane targeting and partner-binding domains of Nvj1p reveal a role in sterol-dependent protein trafficking. David S. Goldfarb, Erik Kvam. Department of Biology, University of Rochester, Rochester, NY 14627. |
| 51 | An intraperoxisomal signaling cascade initiates peroxisome division by triggering the stepwise remodeling of lipid and protein composition of the peroxisomal membrane. Christopher Gregg, Tong Guo, Tatiana Boukh-Viner, Alexander Goldberg, Simon Bourque, Pavlo Kyryakov, Farhana Banu, Karen Hung Yeung San, Cristina Sison, Jonathan Solomon, Vivianne Wong, Oleh Petriv, Vladimir Titorenko. Biology Department, Concordia University, Montreal, Quebec, Canada. |
| 52 | Das Hefeperlenspiel: Life history and genomics of immobilized yeast. R Rosenzweig1, A Kruckeberg1, K McInnerney2, B Myers3, T Taylor3. 1) Div Biol Sciences, Univ Montana, Missoula, MT; 2) Genomics Core, Montana State Univ, Bozeman, MT; 3) Biol Eng, Utah State Univ, Logan, UT. |
| 53 | Using natural variation to uncover post-transcriptional regulatory mechanisms. Aimée Dudley1,3, Suin Lee2,3, Dana Pe'er1, Anupriya Dutta1, George Church1, Daphne Koller2. 1) Department of Genetics, Harvard Medical School, Boston, MA; 2) Computer Science Department, Stanford University, Stanford, CA; 3) equal contributions. |
| 54 | Gene-environment interaction in yeast: the genetic and molecular basis for strain-specific response to condition. Erin Smith1,2, Leonid Kruglyak1. 1) Dept Ecol & Evol Biol, Princeton Univ, Princeton, NJ; 2) Molecular and Cellular Biology, University of Washington, Seattle, WA. |
| 55 | The ability to grow on extreme pH as a model trait for the Genetic Dissection of Quantitative Trait Loci (QTLs). Gal H. Romano, Martin Kupiec. Molec.microbiology and Biotec, Tel Aviv University, Tel Aviv, Israel. |
| 56 | Independent sorting-out of gene pairs formed by genome duplication in Kluyveromyces polysporus and Saccharomyces cerevisiae. Devin R. Scannell, A. Carolin Frank, Kevin P. Byrne, Gavin C. Conant, Kenneth H. Wolfe. Smurfit Institute, Dept. of Genetics, Trinity College Dublin, D2, Ireland. |
| 57 | Evolution of Gene Expression in Experimentally Evolved Yeast. Maitreya Dunham, Cheryl Christianson, Dave Pai. Lewis-Sigler Inst, Princeton Univ, Princeton, NJ. |
| 58 | Splicing is rapidly and specifically regulated in response to environmental changes. Gregg Whitworth, Jeffrey A Pleiss, Megan Bergkessel, Christine Guthrie. Biochemistry & Biophysics, UCSF, San Francisco CA. |
| 59 | The CURI-complex: Potential Link between Production of rRNA and of Ribosomal Proteins? Dipayan Rudra, Jaideep Mallick, Jonathan R. Warner. Dept. of Cell Biology, AECOM, Bronx, NY. |
| 60 | Molecular functions of translation initiation factors eIF1 and eIF1A in preinitation complex assembly, ribosomal scanning and AUG recognition. Alan Hinnebusch1, Christie Fekete1, Drew Applefield2, Yuen Nei Cheung1, David Maag2, Mikkel Algire2, Stephen Blakely1, Nikolay Shirokikh3, Tatyana Pestova3, Jon Lorsch2. 1) Laboratory of Gene Regulation & Development, NICHD, NIH, Bethesda, MD; 2) Dept. of Biophysics and Biophysical Chemistry, Johns Hopkins University School of Medicine, Baltimore, MD; 3) Dept. of Microbiology and Immunology, SUNY-Brooklyn, NY. |
| 61 | Proteasome- and SCF-dependent degradation of yeast adenine deaminase upon transition from proliferation to quiescence requires a new F-box protein named Saf1p. Stephanie Escusa, Damien Laporte, Jurgi Camblong, Benoit Pinson, Bertrand Daignan-Fornier. Inst Biochem & Genetique Cell, CNRS UMR 5095, Bordeaux, France. |
| 62 | Retrotranslocation of a viral A/B toxin from the yeast endoplasmic reticulum is independent of ubiquitination, ERAD and proteasome activity. Manfred Schmitt, Susanne Heiligenstein, Tanja Sendzik, Natalia Jimenez-Becker, Frank Breinig. FR 8.3 Mikrobiologie Geb A l.5, Angewandte Molekularbiologie, Saarbrucken, Germany. |
| 63 | A prion-like phenotype conveys glucosamine resistance in S. cerevisiae. Jessica C. Brown, Susan Lindquist. MIT Biology/Whitehead Institute, MA. |
| 64 | Dissecting the Mechanism of Age-Induced Loss of Heterozygosity. MP Andersen, LL Carr, DE Gottschling, ED Hetrick, DL Lindstrom, ZW Nelson. FHCRC, Seattle, WA. |
| 65 | Free radicals and aging in S. cerevisiae: what can the cells do about it? Nika Erjavec, Thomas Nyström. Dept. of Cell and Molecular Biology, Göteborg University, Box 462, 40530 Göteborg, Sweden. |
| 66 | RHO5 is necessary for maintenance of redox homeostasis in yeast. Komudi Singh, Pil Jung Kang, Hay-Oak Park. Molecular Genetics, The Ohio State University, Columbus, OH. |
| 67 | Rapamycin Activates Tap42-Associated Phosphatases by Abrogating Their Association with Tor Complex 1. Gonghong Yan, Xiaoyun Shen, Yu Jiang. Pharmacology, Univerisity of Pittsburgh, Pittsburgh, PA. |
| 68 | ATG1 regulates filamentous growth independent of autophagy in Saccharomyces cerevisiae. Montrell D Seay, Michael Snyder, Savithramma Dinesh-Kumar. MCDB, Yale University, New Haven, CT. |
| 69 | Isolation and characterization of quiescent (G0) and non-quiescent cells from yeast stationary-phase cultures. Margaret Werner-Washburne1, Chris Allen1, Sabrina Büner3, Anthony Aragon1, Osorio Meirelles5, Sushmita Roy4, Don Benn1, Martin Veenhuis2, Frank Madeo3. 1) Dept Biol, Univ New Mexico, Albuquerque, NM; 2) Laboratory of Eukaryotic Microbiology University of GroningenLaboratory of Eukaryotic Microbiology University of Groningen The Netherlands; 3) Institute for Molecular Biosciences University of Graz Graz, Austria; 4) Department of Computer Sciences University of New Mexico, Albuquerque, NM; 5) Department of Math and Statistics University of New Mexico Albuquerque, NM. |
| 70 | The histone deacetylase Rdp3p coordinates induced and repressed expression changes in yeast cells responding to stress. Adriana Alejandro-Osorio1, Dominic Porcaro2, Audrey Gasch2,3. 1) Department of Biomolecular Chemistry, University of Wisconsin- Madison, Madison, WI; 2) Department of Genetics, University of Wisconsin-Madison, Madison, WI; 3) Genome Center of Wisconsin. |
| 71 | The PDR12-inducing transcription factor War1p undergoes stress-induced conformational changes on the promoter to elicit weak organic acid stress adaptation in yeast. Christa Gregori1, Ingrid Frohner1, Bettina Bauer1, Dorothea Anrather2, Gustav Ammerer2, Karl Kuchler1. 1) Medical University Vienna, Max F. Perutz Laboratories, Department Medical Biochemistry, Dr. Bohr-Gasse 9/2, Vienna, A-1030 Austria; 2) University of Vienna, Max F. Perutz Laboratories, Department of Biochemistry & Molecular Cell Biology, Dr. Bohr-Gasse 9/5, Vienna, A-1030 Austria. |
| 72 | Stress-Induced Destruction of the Yeast C-type Cyclin Involves Nuclear Export and Mitochondrial Association. Katrina Cooper1, Elizabeth Krasley2, Grace Tan1, Michael Mallory1, Randy Strich1. 1) Dept Molecular Biol, UMDNJ-SOM, Stratford, NJ; 2) Dupont Agriculture and Nutrition Group, Stein-Haskell Research Center, Newark DE. |
| 73 | Identification of Proteins that Interact with the ABC Transporter Ycf1p using the Membrane Yeast Two-Hybrid (MbYTH) Split-Ubiquitin System. Christian M Paumi1, Kim Engels2, Kavitha Iyer2, Oleg Georgiev2, Igor Stagljar2, Susan Michaelis1. 1) Cell Biology, Johns Hopkins University, Baltimore, MD; 2) Donnelly Centre for Cellular and Biomolecular Research (CCBR), Department of Biochemistry & Department of Medical Genetics and Microbiology, University of Toronto, Toronto, ON, Canada. |
| 74 | Activity of the arsenic-responsive transcription factor Yap8p is controlled by the ubiquitin-proteasome pathway. Yujun Di, Markus J. Tamás. Cell and Molecular Biology, Göteborg University, Göteborg, Sweden. |
| 75 | Relief of ammonium ion toxicity by amino acid excretion. David Hess1,2, Wen-Yun Lu1,3, Joshua Rabinowitz1,3, David Botstein1,2. 1) Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton NJ, 08544; 2) Department of Molecular Biology, Princeton University, Princeton NJ, 08544; 3) Department of Chemistry, Princeton University, Princeton NJ, 08544. |
| 76 | Nuclear pore association confers optimal expression levels for an inducible yeast gene. Susan Gasser1, Angela Taddei1, Florence Hediger2, Griet Van Houwe2, Veronique Kalck1, Heiko Schober1, Cubizolles Fabien1. 1) Epigenetics, Friedrich Miescher Inst, Basel, CH; 2) University of Geneva, NCCR Frontiers in Genetics, Geneva CH. |
| 77 | A new paradigm for eukaryotic gene regulation. Nayan Sarma, David Buford, Kellie Barbara, Kristine Willis, George Santangelo. Med. Biosci. & Bioinformatics, Univ. of Southern Mississippi, Hattiesburg, MS. |
| 78 | Amplification of Histone Genes in Saccharomyces cerevisiae. Diana E. Libuda, Fred Winston. Department of Genetics, Harvard Medical School, Boston, MA. |
| 79 | Protein Kinase A regulates RNA polymerase III transcription through the nuclear localization of Maf1. JaeHoon Lee1, Rebecca A. Haeusler2, Neelam Desai1, David R. Engelke2, Ian M. Willis1, Robyn D. Moir1. 1) Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461 USA; 2) Department of Biological Chemistry, University of Michigan Medical School, 3200 MSRB III Ann Arbor, MI 48109-0606 USA. |
| 80 | Distribution of RNA Polymerase II on yeast chromosomes and its perturbation by a substitution in Sen1 helicase. Eric J. Steinmetz1, Christopher L. Warren2, Bahman Panbehi1, Aseem Z. Ansari2, David A. Brow1. 1) Dept Biomolecular Chemistry and; 2) Dept Biochemistry, Univ Wisconsin, Madison, WI. |
| 81 | Sense/antisense transcription of the IME4 locus controls a morphogenetic switch in S. cerevisiae. Cintia Hongay, Paula Grisafi, Gerald Fink. Fink Laboratory, Whitehead Institute, Cambridge, MA. |
| 82A | Actin clumps in yeast quiescent cells: an immediately available actin reserve? Isabelle Sagot, Benoit Pinson, Benedicte Salin, Bertrand Daignan-Fornier. Inst Biochem & Genetique Cell, CNRS UMR 5095, Bordeaux, France. |
| 83B | Conserved Actin Cysteine Residues: Oxidative Stress Sensors That Can Regulate Programmed Cell Death in Yeast. Michelle E. Farah, David C. Amberg. Biochemistry, Upstate Medical University, Syracuse, NY. |
| 84C | Incomplete cytokinesis in the filamentous yeast Ashbya gossypii. Andreas Kaufmann, Juliet Odathekal, Hans-Peter Schmitz, Peter Philippsen. Biozentrum, University of Basel, Switzerland. |
| 85A | Identification and Analysis of Genes that Interact with the Spindle Pole Body component Mps3. Adriana Martin1, Charlie Boone2, Sue Jaspersen1. 1) Stowers Institute for Medical Research, Kansas City, MO; 2) Banting & Best Department of Medical Research, Toronto, ON. |
| 86B | The role of actin during Golgi relocalization to the hyphal tip in C. albicans. Padmashree C. G. Rida, Akiko Nishikawa, Catherine A. Menzies, Gena Y. Won, Neta Dean. Biochemistry & Cell Biology, SUNY Stony Brook, Stony Brook, NY. |
| 87C | Kar9p is restricted to one spindle pole body by two distinct phosphorylation mechanisms. Rita Miller, Jeff Moore. Dept Biol, Univ Rochester, Rochester, NY. |
| 88A | Localization of the yeast ortholog of the human Wiskott-Aldrich Syndrome Protein-Interacting Protein (WIP) to the cortical actin cytoskeleton is not essential for endocytosis. Gang Ren1,2,3, Neeyor Bose2, Barbara Winsor3, Alan L. Munn1,2. 1) Institute for Molecular Bioscience, The University of Queensland, St Lucia, Queensland, AUSTRALIA; 2) Institute of Molecular and Cell Biology, A*STAR Biomedical Sciences Institutes, Singapore, 138673, Republic of Singapore; 3) Centre National Recherche Scientifique, Université Louis Pasteur, UMR7156, Strasbourg, 67084, FRANCE. |
| 89B | GTP binding of Bud4 is necessary for proper bud-site selection and for the integrity of septins during cytokinesis. Pil Jung Kang, Hay-Oak Park. Department of Molecular Genetics, Ohio State Univ, Columbus, OH. |
| 90C | Role of actin cytoskeleton and endocytic-vacuolar pathway in prion formation and toxicity in yeast. Nina V Romanova, Elena E Ganusova, Gary P Newnam, Srishti Bhagat, Yury O Chernoff. Georgia Institute of Technology, Atlanta, GA. |
| 91A | Involvement of the transbilayer redistribution of plasma membrane phospholipids in spatial regulation of polarized membrane growth. Koji Saito1, Konomi Fujimura-Kamada1, Utako Kato2, Masato Umeda2, Keith G. Kozminski3, Kazuma Tanaka1. 1) Division of Molecular Interaction, Hokkaido University Graduate School of Medicine, Sapporo, Japan; 2) Division of Molecular Biology and Information, Institute for Chemical Science, Kyoto University, Kyoto, Japan; 3) Departments of Biology and Cell Biology, University of Virginia, Charlottesville, VA. |
| 92B | Phosducin-like Proteins as Modulators of the Chaperonin CCT. Peter Stirling1, Karam Takhar1, Srayko Martin2, José Valpuesta3, Ronald Melki4, Michel Leroux1. 1) Dept Molec Biol & Biochemistry, Simon Fraser Univ, Burnaby, BC, Canada; 2) Max-Planck-Institute of Molecular Cell Biology and Genetics, Dresden, Germany; 3) Centro nacional de biotecnologia, Campus autonoma de universidad de Madrid, Spain; 4) Laboratoire d’enzymologie et biochimie structurales, CNRS, Paris, France. |
| 93C | Characterization of cytokinesis mutants in Saccharomyces cerevisiae. Elizabeth A Vallen1, Lydia Thé1, Jianying Luo2, Nile Chang1, Colin Palmer1, Stacey Prow1, Peter Yang1, Margaret Lippincott1, Masayuki Iwase2, Erfei Bi2. 1) Biology, Swarthmore College, Swarthmore, PA; 2) Cell and Developmental Biology, University of Pennsylvania School of Medicine, Philadelphia, PA. |
| 94A | Pex13p and the actin cytoskeleton. Galina Kaneva1, Alexandre Soulard1, Jan Havlis2, Sylvie Friant1, Anna Shevchenko2, Barbara Winsor1. 1) UMR7156 CNRS - ULP, Génétique moléculaire Génomique et Microbiologie, Dépt. Génétique moléculaire et cellulaire, 21 rue Decartes, Strasbourg; 2) Max Planck Institute for Molecular Cell Biology and Genetics, Pfotenhauerstrasse 108, 01307 Dresden. |
| 95B | A role for the yeast Ubp16 deubiquitylating enzyme in mitochondrial phosphatidylserine transport. Rohan Baker, Marco Girhard. John Curtin School Medical Res, Australian National University, Canberra, Australia. |
| 96C | Molecular Pathways Regulating Aging-dependent Mitochondrial Degeneration. Xin Jie Chen, Xiaowen Wang, Xiaoming Zuo, Blanka Kucejova. Department of Molecular Biolog, UT Southwestern Medical Center, Dallas, TX. |
| 97A | Role of the cytochrome c oxidase subunit II C-terminal domain in membrane insertion and translocation to the mitochondrial intermembrane space. Heather L. Fiumera, Sarah A. Broadley, Thomas D. Fox. Dept Molecular Biol & Genetics, Cornell Univ, Ithaca, NY 14853. |
| 98B | Two vacuolar yeast sugar permeases are involved in response to heat shock and osmotic stress. Carsten Fruehbeis, Eckhard Boles. Institute of Molecular Biosciences, University of Frankfurt, Frankfurt, Germany. |
| 99C | The growth inhibitor, furfural, induces cellular stress signals in Saccharomyces cerevisiae. Steven Gorsich1, J. Michael McCaffery2. 1) Biology Department, Central Michigan University, Mt. Pleasant, MI; 2) Integrated Imaging Center, Biology Department, Johns Hopkins University, Baltimore, MD. |
| 100A | Yme2p is a mediator of nucleoid structure and number in mitochondria of the yeast Saccharomyces cerevisiae. Sujin Park, Mary Thorsness, Karen White, Peter Thorsness. Molecular Biology, University of Wyoming, Laramie, WY. |
| 101B | Peroxin Pex6 Suppresses Age Asymmetry Defects in Mitochondria. Jae-Gu Seo1, Chi-Yung Lai2, Michael Miceli1, Michal Jazwinski1. 1) Biochemistry and Molecular Biology, LSU Health Science Center, New Orleans, LA; 2) Department of Biology, National Changhua University of Education, Changhua, Taiwan ROC. |
| 102C | Maintenance of an energized inner mitochondrial membrane in Saccharomyces cerevisiae lacking mitochondrial DNA. Christopher Smith, Peter Thorsness. Dept Molecular Biol, Univ Wyoming, Laramie, WY. |
| 103A | Biochemical Analyses of Coq7 Protein and Three other Polypeptides Involved in Saccharomyces cerevisiae Coenzyme Q Biosynthetic Pathway. UyenPhuong C. Tran1,2, Beth Marbois2, Peter Gin2, Melissa Gulmezian2, Edward Hsieh2, Ryoichi Saiki2, Catherine F. Clarke1,2. 1) Molecular Biology Institute, UCLA, Los Angeles, CA; 2) Department of Chemistry and Biochemistry, UCLA, Los Angeles, CA. |
| 104B | Oligomeric state of the mitochondrial ADP/ATP carrier studied through the binding stoichiometry of carboxyatractyloside to the carrier. Thomas Nancy, Bertrand Arnou, Veronique Trezeguet, Guy J.-M. Lauquin. LPMC, IBGC, UMR5095 CNRS-Université Bordeaux2, 1, rue Camille Saint-Saëns 33077 Bordeaux cedex, France. |
| 105C | N-linked protein glycosylation in Saccharomyces cerevisiae is regulated by the proteasome. Nicole B. Averbeck1, Xiao-Dong Gao2, Neta Dean1. 1) Dept. of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, NY, 11794-5215; 2) Research Center for Glycoscience, National Institute of Advanced Industrial Science and Technology, Tsukuba 305-8566, Japan. |
| 106A | Distinct cellular responses induced by a misfolded membrane protein with a cytosolic lesion (mutant Ste6p) vs. a misfolded luminal protein (CPY*) reflect distinct arms of ER quality control. Meredith L. Boyle, Susan Michaelis. Department of Cell Biology, The Johns Hopkins University, Baltimore, MD. |
| 107B | Oligomerization and intracellular transport of the yeast plasma membrane ATPase, Pma1. Sujatha Sitaramin, Yu Liu, Amy Chang. Mol Cell Dev Biol, University of Michigan, Ann Arbor, MI. |
| 108C | Effects of the ubiquitin system alterations on the de novo formation and loss of a yeast prion. Tatiana A. Chernova1, Kim D. Allen2, E. Paula Tennant2, Keith D. Wilkinson1, Yury O. Chernoff2. 1) Dept Biochemistry, Emory Univ, Atlanta, GA; 2) School of Biology and Institute for Bioengineering and Bioscience, Georgia Institute of Technology, Atlanta, GA. |
| 109A | The deubiquitinating enzyme Ubp3 functions in the endocytosis and downregulation of an integral plasma membrane protein. Holly C Dippold2, Christopher J Stephan1, Charles Lin1, Sarah Rue1, Scott Emr1,3. 1) Division of Cellular and Molecular Medicine; 2) Division of Biology; 3) Howard Hughes Medical Institute, UCSD, La Jolla, CA. |
| 110B | Rsp5 regulates expression of stress proteins via post-translational modification of Hsf1 and Msn4 in Saccharomyces cerevisiae. Yutaka Haitani, Hiroshi Takagi. Graduate School of Biological Sciences, Nara Institute of Science and Technology, Nara, Japan. |
| 111C | Identification of abnormal protein substrates of the yeast Rsp5 ubiquitin ligase under stresses. Hiroyuki Hiraishi, Hiroshi Takagi. Grad.Schl. Biol. Sci., Nara Inst. Sci. & Tech, Ikoma, Nara, Japan. |
| 112A | Unseeded [PSI+] prion appearance by the addition of short C-terminal extensions to Sup35 constructs. Nancy Kaye Horstman, Irina L. Derkatch. Microbiology, NYU School of Medicine, New York, NY. |
| 113B | A Role for the Yapsins in the Degradation of Misprocessed Proteins within the Secretory Pathway of Saccharomyces cerevisiae. Damian Krysan, Louis Didone. Dept Pediatrics, Univ Rochester, Rochester, NY. |
| 114C | Cell Wall Stress Increases Tolerance of Misfolded Protein Toxicity Through an Ire1p -independent Mechanism in Saccharomyces cerevisiae. Damian Krysan, Louis Didone. Dept of Pediatrics, University of Rochester, Rochester, NY. |
| 115A | Out of the ER: The role of Gsf2 in the early secretory pathway. Doreen Ochmann, Tanja Hamacher, Eckhard Boles. Institute of Molecular Biosciences, University of Frankfurt, Frankfurt Germany. |
| 116B | Glucose-regulated ubiquitylation of the Jen1 permease of Saccharomyces cerevisiae . Sandra Paiva1, Danièle Urban-Grimal2, Rosine Haguenauer-Tsapis2, Casal Margarida1. 1) Biology, University of Minho, Braga, Braga, Portugal; 2) Institut Jacques-Monod 2, place Jussieu - 75251 Paris cedex 05 - France. |
| 117C | Sts1: A novel regulator of protein degradation by the ubiquitin/proteasome system. Lizbeth Romero-Perez, Li Chen, Gopala Kovvalli, David Lambertson, Kiran Madura. Dept Biochemistry, UMDNJ-Graduate School of Biomedical Sciences, Piscataway, NJ. |
| 118A | Interactions between amyloidogenic proteins. Eric D. Ross. Biochemistry & Molecular Bio., Colorado State University, Fort Collins, CO. |
| 119B | Dissecting toxin immunity in virus-infected killer yeast uncovers an intrinsic strategy of self-protection. Manfred Schmitt, Tanja Sendzik, Frank Breinig. FR 8.3 Mikrobiologie Geb A l.5, Angewandte Molekularbiologie, Saarbruecken, Germany. |
| 120C | Ubiquitin-dependent Degradation of the Mating-Type Regulator Mata1. Christina E. Sowards, Jeffrey D. Laney. Brown University , Providence, RI. |
| 121A | Saccharomyces cerevisiae Nha1 antiporter is a very stable plasma membrane protein. Hana Flegelova1, Rosine Haguenauer-Tsapis2, Hana Sychrova1. 1) Dept Membrane Transport, Inst Physiology, Prague 4, Czech Republic; 2) Institute Jacques Monod-CNRS, Universites Paris VI and VII, Paris, France. |
| 122B | Identification of Hex3•Slx8 as a potential dual-function E3 complex in Saccharomyces cerevisiae. Yang Xie, Oliver Kerscher, Mary Kroetz, Mark Hochstrasser. Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT. |
| 123C | Characterization of nuclear localization signal (NLS) and nuclear export signal (NES) of Pan1, a yeast actin cytoskeleton-associated protein. Joanna Kaminska, Magdalena Sedek, Monika Wysocka-Kapcinska, Teresa Zoladek. Dept Genetics, Inst Biochem Biophys PAS, Warsaw, Poland. |
| 124A | Genomic and genetic strategies identify genes that promote yeast growth in the presence of myriocin, an inhibitor of sphingolipid biosynthesis. Nick F. Abbate1, Geert Bultynck1, Corey Nislow2, Guri N. Giaever2, Martha S. Cyert1. 1) Biological Sciences, Stanford University, Stanford, CA; 2) Genetics Dept, Stanford University School of Medicine, Stanford, CA. |
| 125B | Hsp90 in the glucose/cAMP response pathway in Schizosaccharomyces pombe. Manal Alaamery, Charles Hoffman. Department of Biology, Boston college ,Chestnut Hill, MA 02467,USA. |
| 126C | Signaling alkaline pH stress through the Wsc1-Slt2 pathway in S. cerevisiae. Joaquin Arino, Raquel Serrano, Amparo Ruiz, Laia Viladevall, Loli Bernal, María Platara, Antonio Casamayor. Dept. of Biochemistry & Mol. Biol, Universidad Autonoma Barcelona, Barcelona, Spain. |
| 127A | Beyond Pheromones: Chemical Detectors Based On Engineered Yeast Strains. Addison D. Ault, James R. Broach. Molecular Biology, Princeton University, Princeton, NJ. |
| 128B | DEP Domains Link a Regulator-of-G-Protein-Signaling Protein to its Cognate G-Protein-Coupled Receptor. Daniel Ballon, Jeremy Thorner. Department of Molecular & Cell Biology, University of California, Berkeley, Berkeley, CA. |
| 129C | Novel insights into the regulation of yeast MAPKs by the dual specificity phosphatase Msg5. M Flández, M. J. Marín, C. Bermejo, E. Tapia, J. Arroyo, H. Martín, M. Molina. Dpto. Microbiologia II, Facultad de Farmacia, Universidad Complutense de Madrid, 28040 Spain. |
| 130A | Yeast Gcn4p stabilization is initiated by the dissociation of the nuclear Pho85/Pcl5 complex. Katrin Boemeke, Gerhard Braus. Microbiol/Gen, Molec Microbiol, Georg-August Univ, Gottingen, Germany. |
| 131B | Nutritional control of the TEA/ATTS family transcription factor Tec1. Stefan Brückner, Raphael Birke, Sandra Kern, Barbara Heise, Hans-Ulrich Mösch. Dept. of Biology - Genetics, Philipps University, Marburg, Hessen, Germany. |
| 132C | Glucose-regulated localization of Msi1, a yeast homolog of human retinoblastoma binding proteins. Thomas D. Buford, Terry Haley, Kristina Clarke, Erica Thompson, Baobin Kang, George Santangelo. Med. Biosci. & Bioinformatics, Univ. of Southern Mississippi, Hattiesburg, MS. |
| 133A | Regulation of Signaling Components During Nutrient Responsive Development. Raymond E Chen, Jeremy Thorner. Department of Molecular and Cell Biology, UC Berkeley, Berkeley, CA. |
| 134B | Use of Bimolecular Fluorescence Complementation (BiFC) to study in vivo interaction between Cdc42p and Rdi1p in S. cerevisiae. Karen C Cole, Douglas I Johnson. Microbiology and Molecular Genetics, University of Vermont, Burlington, VT. |
| 135C | Targeted analysis of Gpa1 interface loop regions to determine a mechanism for activation by the a-factor pheromone receptor (Ste2). Stacy L. DeBlasio, James B. Konopka. Microbiology, State University of New York at Stony Brook, Stony Brook, NY. |
| 136A | A novel kinase-substrate binding assay identifies potential docking sites in substrates of the cAMP-dependent protein kinase (PKA) in S. cerevisiae. Stephen J. Deminoff, Susie C. Howard, Paul K. Herman. Dept. of Molecular Genetics, The Ohio State University, Columbus, OH. |
| 137B | The Slt2p Cascade Regulates ER Inheritance. Yunrui Du, Lee Walker, Peter Novick, Susan Ferro-Novick. Cell Biology, HHMI/Yale University, New Haven, CT. |
| 138C | Intracellular Gln3 localization does not always correlate with rapamyin-induced, NCR-sensitive gene expression. E Dubois1, A Feller1, F Vierendeels1, JJ Tate2, TG Cooper2. 1) Lab Microbiologie ULB, IRMW-CERIA, Brussels, Belgium; 2) Dept of Mol Sci, Univ Tennessee, Memphis, TN. |
| 139A | Subunit interactions within the Snf1 kinase complex. Karin Elbing, Eric M Rubenstein, Rhonda R McCartney, Martin C Schmidt. Mol Gen & Biochem, University of Pittsburgh, Pittsburgh, PA. |
| 140B | Intrinsically active variants (MAPKK-independent) of Hog1/p38 and Mpk1/ERK MAP kinase - mechanism of action and biological activities. David Engelberg, Inbal Maayan, Vered Levin, Nadav Askari, Ron Diskin, Michal Avitzour, Irit Marbach, Oded Livnah. Dept Biol/Chem, Inst Life Sci, Hebrew Univ of Jerusalem 91904, Jerusalem, Israel. |
| 141C | Control of signaling in a MAP-kinase pathway by an RNA-binding protein. Susanne Prinz1, Christine Aldridge1, Stephen Ramsey1, James Taylor1,2, Bruz Marzolf1, Timothy Galitski1,2. 1) Institute for Systems Biology, Seattle, WA; 2) University of British Columbia, Vancouver, BC. |
| 142A | Ras, pseudohyphal growth, and biofilm formation in S. cerevisiae. Cemile Guldal1, Holly Koblish1, Giorgia Pirino1, Lisa Schneper1, Ying Wang1, Corey Davis1, Ashton Breitkreautz2, Michael Tyers2, James Broach1. 1) Dept Molecular Biol, Princeton Univ, Princeton, NJ; 2) Department of Medical Genetics and Microbiology, University of Toronto, Toronto ON, Canada. |
| 143B | Phosphorylation of Cdc37 controls its interaction with Hsp90 and influences HOG and PKC MAP kinase pathway activity. Patricija Hawle, Danielle Horst, Jan Paul Bebelman, Xiao-Xian Yang, Marco Siderius, Saskia M. van der Vies. Biochemistry&Molecular Biology, Vrije Universiteit, Amsterdam, Netherlands. |
| 144C | Role of KlMth1 in glucose signaling in Kluyveromyces lactis. Martina Hnatova, Marc Lemaire, Micheline Wésolowski-Louvel. UMR5122 Microbiologie et Génétique, Université Claude Bernard Lyon1, Villeurbanne, France. |
| 145A | Regulation of TOR signaling by ubiquitination. Kejin Hu, Yu Jiang. Pharmacology, University of Pittsburgh, Pittsburgh, PA 15261. |
| 146B | Mining G protein structure-function via genetic analysis in Schizosaccharomyces pombe. F. Douglas Ivey, Fran Taglia, Fan Yang, Matt Ziparo, Charles Hoffman. Dept of Biology, Boston College, Chestnut Hill, MA. |
| 147C | Multiple levels of control of Msn2 with an original behaviour of nucleocytoplasmic shuttling of its molecular population upon stress. Michel Jacquet1, Cécilia Garmendia1, Hervé Garreau1, Sylvie Lallet2, Emmanuelle Boy-Marcotte1, Albert Goldbeter3. 1) IGM, Univ Paris-XI-Sud, Orsay, France; 2) UMR-CNRS-6061 Univ Rennes1, Rennes, France; 3) Univ libre, Bruxelles, Bruxelles, Belgium. |
| 148A | Large-Scale Deletion and Over-expression Analyses of Filamentous-Form Growth in Budding Yeast. Rui Jin, Craig Dobry, Anuj Kumar. Life Sciences Institute, University of Michigan, Ann Arbor, MI. |
| 149B | The Yak1 kinase is required for Msi1p/Cac3p to join the chromatin assembly complex and to activate transcription in the absence of fermentable carbon sources. Stephen Johnston1, Zachary Pratt1, Jason Karpus1, Mary Miller2. 1) Department of Biology, North Central College, Naperville, IL; 2) Department of Biology, Rhodes College, Memphis, TN. |
| 150C | The role of the Sch9 signaling kinase in the integration of environmental cues in growth and stress response regulation in the yeast, Saccharomyces cerevisiae.. Timothy Lee, Huma Safdar, John D. Wagner. Dept. of Biology, Haverford College, Haverford, PA. |
| 151A | HOG pathway in the halophilic yeast: is the existence of multiple isoforms of Pbs2 responsible for its extreme adaptability? Metka Lenassi, Ana Plemenitaš. Institute of Biochemistry, Faculty of Medicine, Ljubljana, Slovenia. |
| 152B | The PKC pathway may govern Saccharomyces membrane fluidity. Daniel Lockshon, Emily Kerr, Brian Kennedy. Dept of Biochemistry, UW, Seattle, WA. |
| 153C | Microarray Analysis Reveals Link Between Filamentous Growth and Autophagy in Budding Yeast. Jun Ma1, Rui Jin1, Xiaoyu Jia1, Craig J Dobry1, Li Wang2, Fulvio Reggiori1, Daniel J Klionsky1, Ji Zhu2, Anuj Kumar1. 1) Department of MCDB and Life Sciences Institute, University of Michigan, Ann Arbor, MI 48109-2216; 2) Department of Statistics, University of Michigan, Ann Arbor,MI 48109-1107. |
| 154A | Gln3 is required for the caffeine sensitivity of a Saccharomyces cerevisiae disruptant of the protein phosphatase Ppz1. Hirasaki Masataka, Horiguchi Masaya, Kaneko Yoshinobu, Harashima Satoshi. Biotechnology, Osaka University, Suita, Osaka, Japan. |
| 155B | Probing the Cla4 synthetic lethal network. Emily M. Mazanka, Eric L. Weiss. BMBCB, Northwestern University, Evanston, IL. |
| 156C | A delicate balance of gene expression controls developmental choices. Lois E. Murray. Microbiology and Immunology, Faculty of Medicine, Dalhousie University , Halifax, Nova Scotia, Canada. |
| 157A | Differential regulation of Skn7 and Hsf1 by the three PKA catalytic subunits in Saccharomyces cerevisiae. Jorge Nieto-Sotelo, Claudia Martínez-Anaya, Sergio Pérez-Landero, Luz M. Martínez. Instituto de Biotecnología, UNAM, Cuernavaca, Morelos, Mexico. |
| 158B | A novel regulation of the Snf1-complex in yeast. Daniel Bosch, Lena Gustafsson, Joakim Norbeck. Molecular Biotechnology, Chalmers University of Technology, Goteborg, Sweden. |
| 159C | Structure function analysis of Hph1: a novel calcineurin substrate that regulates metal ion homeostasis. Francisco J. Pina, Allyson F. O'Donnell, HaiLan Piao, Victoria Heath, Martha S. Cyert. Dept. of Biological Sciences, Stanford University, Stanford, CA. |
| 160A | Glycerol-3-phosphate is a non-transported agonist of the yeast Pho84 transporter-receptor that mediates rapid phosphate activation of the PKA pathway. Yulia Popova, Elena Lonati, Johan Thevelein. Molecular Microbiology, KULeuven, VIB, Leuven-Heverlee, Brabant, Belgium. |
| 161B | Regulatory domains of the Snf1-activating kinases, Sak1, Tos3, and Elm1, determine pathway specificity. Eric M. Rubenstein, Martin C. Schmidt. Biochemistry & Molec. Genetics, University of Pittsburgh, Pittsburgh, PA. |
| 162C | Alkaline stress in the yeast Saccharomyces cerevisiae results in transcriptional changes that mimic glucose-limiting conditions. Amparo Ruiz, Maria Platara, Raquel Serrano, Antonio Casamayor, Joaquín Ariño. Bioquimica i Biol. Molecular, Fac. Veterinaria, Universitat Autonoma Barcelona, 08193-Cerdanyola, Barcelona, Spain. |
| 163A | Transcriptional profiling of the protein phosphatase 2C family in yeast reveals a unique role of Ptc1 in cell wall integrity. Raquel Serrano, Asier González, Amparo Ruiz, Joaquín Ariño, Antonio Casamayor. Dept. Bioquimica i Biol. Molecular, Fac. Veterinaria Universitat Autonoma Barcelona, 08193 Cerdanyola, Barcelona, Spain. |
| 164B | Cell Wall Perturbations Stimulate the SLN1 Histidine Kinase via a Turgor-Independent Mechanism. Sandhya Shankarnarayan1, Cherie L. Malone1, Robert J. Deschenes2, Jan S. Fassler1. 1) Biological Sciences, University of Iowa, Iowa City, IA; 2) Department of Biochemistry, Medical College of Wisconsin, Milwaukee, WI. |
| 165C | A Novel Feedback Mechanism That Downregulates the Cell Wall Integrity Pathway. Xiaoyun Shen, Yu Jiang. Department of Pharmacology, University of Pittsburgh, Pittsburgh, PA. |
| 166A | Engineered Post-Translational Logic in Saccharomyces cerevisiae. Samantha C Sutton, Drew Endy. Biological Engineering, MIT, Cambridge, MA. |
| 167B | The MAP kinase Hog1p modulates Fps1p-dependent arsenite uptake and tolerance in yeast. Michael Thorsen1, Yujun Di1, Carolina Tängemo1, Montserrat Morillas2, Francesc Posas2, Robert Wysocki3, Markus J. Tamás1. 1) Cell and Molecular Biology , Göteborg University, Göteborg, Sweden; 2) Cell Signalling Unit, Universitat Pompeu Fabra, Barcelona, Spain; 3) Institute of Genetics and Microbiology, Wroclaw University, Wroclaw, Poland. |
| 168C | Nitrogen source-independent dephosphorylation of Gln3 by Sit4 phosphatase. JJ Tate1, A Feller2, E Dubois2, TG Cooper1. 1) Dept Molecular Sci, Univ Tennessee, Memphis, TN; 2) Inst Rech Microbiol, JM Wiame Microbiology ULB, Bruxelles, Belgium. |
| 169A | Regulation of Gln3 Localization in Saccharomyces cerevisiae by Protein Kinase Npr1. JJ Tate, R Rai, TG Cooper. Dept Mol Sci, Univ Tennessee, Memphis, TN. |
| 170B | The sugar sensing GPCR Gpr1 mediates pseudohyphal growth on sucrose in non-inducing conditions. Sam Van de Velde, Johan Thevelein. Laboratory of Molecular Cell Biology (VIB10), KULeuven, Leuven, Belgium. |
| 171C | Control of septin assembly and function by phosphoinositides and a Cdc42-activated protein kinase, Cla4, in budding yeast. Violet Votin, Jeremy Thorner. Molecular and Cell Biology, UC Berkeley, Berkeley, CA. |
| 172A | Polarization of Yeast Cells in Spatial Gradients of Alpha-Factor Generated by Microfluidics. Travis Moore1, Noo Li Jeon2, Tau-Mu Yi1. 1) Dept Dev & Cell Biol, Univ California, Irvine, Irvine, CA; 2) Dept Biomedical Engineering, Univ California, Irvine, Irvine, CA. |
| 173B | Assessing the role of Tor in nutrient sensing through global transcriptional analysis. xin zhao, Soyeon Im, James Broach. Molecular Biology, Princeton University, Princeton, NJ. |
| 174C | Functional Analysis of EFG1: a Novel Gene Required for Cell Cycle Progression in S. cerevisiae. Ayça Akal-Strader, Wei-Chun Au, Munira A. Basrai. Genetics Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD. |
| 175A | Ribosome biogenesis directly promotes passage at Start through Whi5, the yeast homologue of Rb. Kara Bernstein1, Franziska Bleichert1, Jamie Bean4, Frederick R. Cross4,5, Susan J. Baserga1,2,3,5. 1) Department of Genetics, Yale University, New Haven, CT; 2) Department of Molecular Biochemistry and Biophysics, Yale University, New Haven, CT; 3) Department of Therapeutic Radiology, Yale University, New Haven, CT; 4) Rockefeller University, New York, NY; 5) These authors contributed equally to this work. |
| 176B | Ypi1: An Inhibitor or Activator of Protein Phosphatase Type 1? Jennifer Bharucha, Kelly Tatchell. Dept Biochem & Molec Biol, LSUHSC, Shreveport, LA. |
| 177C | Metabolism and death during nutrient starvation in Saccharomyces. Viktor M Boer1,2, David Botstein1,2. 1) Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton NJ, 08544; 2) Department of Molecular Biology, Princeton University, Princeton NJ, 08544. |
| 178A | The Transcriptional Response to Differences in Growth Rate May Account for Most of the Generic Stress Response. Matthew Brauer1,2, Rachel Rosenstein2, Morten Kloster3, Ned Wingreen1, David Botstein1,2. 1) Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ; 2) Dept. of Molecular Biology, Princeton University, Princeton, NJ; 3) The California Institute for Quantitative Biomedical Research, University of California, San Francisco, CA. |
| 179B | Mutants in the CRISP superfamily Pathogenesis-Related proteins of yeast (PRY) are sensitive to environmental insults. Adrian Bruning, Andrew Vershon. Waksman Inst, Rutgers Univ, Piscataway, NJ. |
| 180C | A size control model for Start in slowly-growing cells. Lucas Carey, Bruce Futcher. Microbiology, Stony Brook University, Stony Brook, NY. |
| 181A | Kljen1 and Kljen2 are essencial for the transport of monocarboxylic and dicarboxylic acids in the yeast Kluyveromyces lactis. Odília Queirós1,2,3, Leonor Pereira1,2, Sandra Paiva1, Pedro Moradas-Ferreira2,4, Margarida Casal1. 1) Dept Biol, Univ do Minho, Braga, Portugal; 2) Unidade de Microbiologia Celular e Aplicada, Instituto de Biologia Molecular e Celular, Porto; 3) Departamento de Ciencias, Instituto Superior de Ciencias da Saude-Norte, Paredes; 4) Instituto de Ciencias Biomedicas Abel Salazar, Porto,. |
| 182B | Spindle checkpoint effectors, Cdc20 and Cdh1, and checkpoint factor Mad2p, regulate polarized growth in C. albicans. Hsin-I Chou, Catherine Bachewich. Biology, Concordia University, Montreal, PQ, CANADA. |
| 183C | Regulated proteolysis of Dbf4p in Saccharomyces cerevisiae. Bernadette Connors, Lindsey Gaskin, Mohammed Hajj. Department of Biology, Millsaps College, Jackson, MS. |
| 184A | Orc6 mediates MCM chromatin association and is required for initiation of DNA replication after pre-replicative complex formation. Jeffrey W. Semple1, Lance F. Da-Silva1, Eric J. Jervis2, Jennifer Ah-Kee3, Hyder Al-Attar1, Lutz Kummer1, Philippe Pasero3, Bernard P. Duncker1. 1) Department of Biology, University of Waterloo, Waterloo, Ontario, Canada; 2) Department of Chemical Engineering, University of Waterloo, Ontario, Canada; 3) Institute of Human Genetics, CNRS, Montpellier, France. |
| 185B | Targets of the Swi5 and Ace2 transcription factors, and their effect on budding in daughters. Bruce Futcher1, Adam Rosebrock1, Jamie Bean2, Stefano Di Talia2, Fred Cross2. 1) Dept Microbiology, SUNY Stony Brook, Stony Brook, NY; 2) Rockefeller University, 1230 York Ave., NY, NY 10021. |
| 186C | Lipotoxicity in Yeast: a model for several human diseases. Jeanne A. Garbarino1, Mahajabeen Padempsee1, Oelkers Peter1, Stephen L. Sturley1,2. 1) Insitute of Human Nutrition, Columbia University, New York, NY; 2) Department of Pediatrics, Columbia University, New York, NY. |
| 187A | Identification of genes affecting glucose catabolism in nitrogen-limited fermentation. Jennifer M Gardner, Miguel de Barros Lopes, Vladimir Jiranek. Agriculture and Wine, University of Adelaide, Urrbrae, South Australia, Australia. |
| 188B | In silico modelling of key processes involved in the initiation of DNA replication. Rohan D. Gidvani, Zhenyu Cheng, DongRyoung Kim, Brian Ingalls, Bernard P. Duncker, Brendan J. McConkey. Biology, University of Waterloo, Waterloo, Ontario, Canada. |
| 189C | Regulation of G1 progression in Saccharomyces cerevisiae. Matthew G. Slattery1, Dritan Liko2, Michael J. Dapp1, Warren Heideman1,2. 1) School of Pharmacy, University of Wisconsin, Madison, WI; 2) Department of Biomolecular Chemistry, University of Wisconsin, Madison, WI. |
| 190A | Characterisation of the Saccharomyces cerevisiae cell separation machinery. Hsueh-lui Ho, Ken Haynes. Department of Molecular Microbiology and Infection, Imperial College London, London, United Kingdom. |
| 191B | A chemical genetic approach to uncover the role of Sir2 in reactive carbonyl stress tolerance. Shawn S Hoon, Guri Giaever, Ronald W Davis, Corey Nislow. Genetics, Stanford University, Stanford, CA. |
| 192C | The Pho85 cyclin dependent kinase regulates G1 transcription via phosphorylation of the transcription inhibitor Whi5. Dongqing Huang, Michael Costanzo, Nazareth Bastajian, Supipi Kaluarachchi, Jonathan Millman, Richelle Sopko, Brenda Andrews. CCBR, Univ Toronto, Toronto, ON, Canada. |
| 193A | Regulation of G1 phase and development in C. albicans. Catherine Bachewich1, Bahira Hussein1, Loius-Pierre Asselin-Jarry1, Andre Nantel2, Malcolm Whiteway2. 1) Biology Department, Concordia University, Montreal, QC, Canada; 2) BRI/NRC, Montreal, QC. Canada. |
| 194B | Identification of Saccharomyces cerevisiae Ribosomal Protein L3 as a Target of Curvularol, a G1-Specific Inhibitor of Mammalian Cells. Yoshifumi Kobayashi1, Masaki Mizunuma1, Hiroyuki Osada2, Tokichi Miyakawa1. 1) Molecular Biotechnology, Hiroshima University, Kagamiyama 1-3-1, Higashi-Hiroshima, Hiroshima, 739-8530, Japan; 2) Antibiotics Laboratory, RIKEN, Hirosawa 2-1, Wako, Saitama, 351-0918, Japan. |
| 195C | Regulation of Lipolysis in Yeast. Christoph F. Kurat, Heimo Wolinski, Klaus Natter, Regina Leber, Sepp D. Kohlwein. Biochemistry, IMB, Graz, Styria, Austria. |
| 196A | Inhibition of the RAM signaling network Cbk1 kinase severely delays bud emergence and triggers the morphogenesis checkpoint. Cornelia Kurischko1, Pavel Nazarov1, Michelle Ottey1, Kevan Shokat2, Frank Luca1. 1) Dept Animal Biol, Sch Vet Med, Univ. of Pennsylvania, Philadelphia, PA; 2) Univ. of California, San Francisco, CA. |
| 197B | Cdc55p-dependent PP2A regulates G1 cell cycle progression. Paula C. McCourt, Joseph T. Nickels. Drexel Univ Col Medicine, Dept Biochemistry & Molec Biol, Philadelphia, PA. |
| 198C | Genetic Interactions of the Saccharomyces cerevisiae KIN3 Gene. Sarah L. McGuire, John Gibson, Yulon Stewart, Michael P. Jackson. Dept Biology, Millsaps College, Jackson, MS. |
| 199A | Following nuclear envelope fission in budding yeast. Patricia Melloy, Mark Rose. Molecular Biology, Princeton University, Princeton, NJ. |
| 200B | Identification of Genes Important for the Activity of the G1 Cyclin Cln3 Nuclear Localization Signal in S. cerevisiae. Mary Miller1, Brenda Andrews2, Richelle Sopko2. 1) Department of Biology, Rhodes College, Memphis, TN; 2) Department of Medical Genetics and Microbiology, University of Toronto, Toronto Ontario. |
| 201C | Trs120p is required for cell morphogenesis and division in C. albicans. Klarita Mogilevsky1, Susan Kaminskyj2, Catherine Bachewich1. 1) Biology, Concordia University, Montreal, Quebec, Canada; 2) Biology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada. |
| 202A | Search for novel targets of the anaphase promoting complex (APC). Denis Ostapenko, Janet Burton, Mark Solomon. Department Molecular Biophysics Biochemistry, Yale University, New Haven, CT 06520. |
| 203B | The catalytic activity of several pathogenic enzyme variants per se is not affected in triosephosphate isomerase deficiency. Markus Ralser1, Gino Heeren2, Michael Breitenbach2, Hans Lehrach1, Sylvia Krobitsch1. 1) Dep. of Vertebrate Genomics (Prof. Hans Lehrach), Max-Planck Institute for Molecular Genetics, Berlin, Germany; 2) Department of Cell Biology, University of Salzburg, Hellbrunnerstrasse 34, 5020 Salzburg, Austria. |
| 204C | Characterization of Dbf4 interactions with DNA replication and cell cycle checkpoint factors in S. cerevisiae. Matthew D. Ramer, Ajai A. Prasad, Karen Stanger, Martina Spranger, Bernard P. Duncker. Department of Biology, University of Waterloo, Waterloo, Ontario, Canada. |
| 205A | The role of PKA phosphorylation in the regulation of autophagy. Joseph Stephan, Paul Herman. Dept Molecular Genetics, Ohio State Univ, Columbus, OH. |
| 206B | N-Acetyltransferase Mpr1 confers oxidative stress tolerance on Saccharomyces cerevisiae by reducing reactive oxygen species. Xiaoyi Du2, Hiroshi Takagi1. 1) Graduate School of Biological Sciences, Nara Institute of Science and Technology, Nara, Japan; 2) Department of Bioscience, Fukui Prefectural University, Fukui, Japan. |
| 207C | Caloric restriction extends life span via regulated synthesis and degradation of lipids. Fusheng Tang1, Joseph W. Watkins1, Maria F. Bermudez1, Gheorghe Gracium2. 1) Department of Biology, University of Arkansas Little Rock, Little Rock, AR 72204; 2) Department of Mathematics, University of Wisconsin-Madison, WI 53706. |
| 208A | Mechanisms of aging in yeast. Alexander Goldberg, Christopher Gregg, Tatiana Boukh-Viner, Simon Bourque, Pavlo Kyryakov, Tong Guo, Oleh Petriv, Vladimir Titorenko. Biology Department, Concordia University, Montreal, Quebec, Canada. |
| 209B | Involvement of calcineurin-dependent degradation of Yap1p in Ca2+-induced G2 cell-cycle regulation in Saccharomyces cerevisiae. Hiroshi Yokoyama, Masaki Mizunuma, Michiyo Okamoto, Josuke Yamamoto, Dai Hirata, Tokichi Miyakawa. Molecular Biotechnology, Hiroshima Univ., Higasi-Hirosima, Hiroshima, Japan. |
| 210C | Regulation of cell morphogenesis by G1 cyclin-dependent kinases in budding yeast. Jian Zou1,3, Brenda Andrews1,2,3. 1) Donnelly CCBR, Univ Toronto, Toronto, ON, Canada; 2) Banting and Best Department of Medical Research, Univ Toronto, Toronto, ON, Canada; 3) Department of Medical Genetics and Microbiology, Univ Toronto, Toronto, ON, Canada. |
| 211A | A tetraploid, dioecious, population of Saccharomyces cerevisiae. Michel Aigle1, Rim Al Safadi1, Jerome Briolay2. 1) UMR5122, CNRS/INSA/Univ Lyon1, VILLEURBANNE, France; 2) DTAMB,Univ Lyon1, VILLEURBANNE, France. |
| 212B | Regulation of the Cdc42 GTPase module during cell fusion in Saccharomyces cerevisiae. Sophie Barale1, Derek McCusker2, Robert A. Arkowitz1. 1) Institute of Signaling, Developmental Biology, and Cancer, CNRS UMR 6543, Université de Nice, Faculté des Sciences-Parc Valrose, 06108 Nice Cedex 2, France; 2) Department of Biology, Sinsheimer Laboratories, University of California at Santa Cruz, Santa Cruz, California 95064. |
| 213C | Role of Ume6 in silencing of the cryptic mating type loci in Kluyveromyces lactis. Emad Barsoum, Stefan Åström. Stockholm University, Developmental biology, Wenner-Gren Institute, Stockholm, Stockholm, Sweden. |
| 214A | Cell-type control of IME4 mRNA accumulation in yeast. Mary J. Clancy, Brandy P. Huderson, Ashley Y. Jackson, John D. Marker, Candace S. Timpte. Dept Biological Sci, Univ New Orleans, New Orleans, LA. |
| 215B | Examining the roles of the CDC7 and DBF4 genes during Saccharomyces cerevisiae meiosis. Anne Galbraith, David Ellingson, Richard Tommy, Jedediah Jensen. Dept Biol, Univ Wisconsin, La Crosse, La Crosse, WI. |
| 216C | The role of the Meiosis II outer plaque in membrane formation in Saccharomyces cerevisiae. Erin M Mathieson, Aaron Neiman. Biochemistry, SUNY Stony Brook, Stony Brook, NY. |
| 217A | Regulation of Sum1p by the meiosis-specific protein kinase Ime2p. Michael Moore1, Kristin Servent1, Edward Winter1, Adrian Brunning2, Andrew Vershon2. 1) Department of Biochemistry and Molecular Pharmacology, Thomas Jefferson University, Philadelphia, PA; 2) Waksman Institute and Department of Molecular Biology and Biochemistry, Rutgers University, Piscataway, NJ. |
| 218B | Dissecting phenotypic variability during meiosis. Iftach Nachman1, Aviv Regev1, Sharad Ramanathan1,2. 1) Bauer Center for Genomics Research, Harvard University, Cambridge, MA; 2) Bell Laboratories, 600 Mountain Av., Murray Hill, NJ. |
| 219C | A systems biology approach to studying the yeast pheromone sensing pathway. Saurabh Paliwal1, Zoe Hilioti1, Pablo Iglesias2, Marcus Goncalves1, Alex Groisman3, Andre Levchenko1. 1) Biomedical Engineering, The Johns Hopkins University, Baltimore, MD; 2) Electrical and Computer Engineering department, The Johns Hopkins University, Baltimore, MD; 3) Department of Physics, University of California at San Diego, La Jolla, CA. |
| 220A | GAS2 and GAS4 : a pair of developmentally regulated genes involved in spore wall assembly in yeast. Laura Popolo1, Enrico Ragni1, Josè Rodriguez-Pena2, Alison Coluccio3, Javier Arroyo2, Aaron Neiman3. 1) Dipartimento di Scienze biomolecolari e Biotecnologie, Università di Milano, Milano, Italia; 2) Departamento de Microbiologia II, Universidad Complutense de madrid, Madrid; 3) Department of Biochemistry and Cell Biology, SUny, Stony Brook, NY. |
| 221B | Ubiquitin-like (UBL) domain protein Mdy2 is required for nuclear migration in the pre-zygote in Saccharomyces cerevisiae. Zheng Hu, Harald Bielig, Cornelis Hollenberg, Massoud Ramezani Rad. Inst Microbiology, Heinrich-Heine Univ, Dusseldorf, Germany. |
| 222C | The Role of Prm3p in Yeast Nuclear Fusion. Shu Shen, Mark Rose. Molecular Biology, Princeton University, Princeton, NJ. |
| 223A | Checkpoint-mediated regulation of expression of Ndt80, a transcriptional activator of middle sporulation-specific genes. Ghadeer Shubassi, Jacqueline Segall. Department of Biochemistry, University of Toronto, Toronto, ON, CANADA. |
| 224B | The leading edge complex mediates organellar segregation during sporulation. Yasuyuki Suda, Aaron Neiman. Biochemistry and Cell Biology, SUNY Stony Brook, Stony Brook, NY. |
| 225C | Quantitative dependence of heterotrimeric G-protein signaling on levels of receptor and RGS protein. Hiromasa Tanaka1, Hiroaki Kitano2,3,4,5, Tau-Mu Yi1. 1) Dept of Dev & Cell Biology, UCI, Irvine, CA; 2) The Systems Biology Institute, Tokyo, Japan; 3) Department of Fundamental Science and Technology, Keio University, Tokyo, Japan; 4) ERATO-SORST Kitano Symbiotic Systems Project, Japan Science and Technology Agency, Tokyo, Japan; 5) Sony Computer Science Laboratories, Inc, Tokyo, Japan. |
| 226A | Nud1, the yeast homologue of Centriolin, is required for spindle pole body inheritance in yeast meiosis. Oren Gordon2, Christof Taxis1, Philipp Keller1, Aleksander Benjak1, Ernst H. K. Stelzer1, Giora Simchen2, Michael Knop1. 1) Dept Cell Biol & Biophysics, EMBL, Heidelberg, Germany; 2) Department of Genetics, The Hebrew University of Jerusalem, Jerusalem 91904, Israel. |
| 227B | KRE6 BOTH PROMOTES AND INTERFERES WITH MATING AT TWO STEPS OF THE MATING PATHWAY. Casey A Ydenberg, Dina P Matheos, Mark D Rose. Department of Molecular Biology, Princeton University, Princeton, NJ 08544. |
| 228C | Increased abundance of the Age1 ArfGAP or the Sfh2 lipid-transfer protein restores an essential vesicular-transport activity. Jeremy J.R. Benjamin1, Pak Phi Poon1,2, Richard A. Singer2, Gerald C. Johnston1. 1) Microbiology and Immunology, Dalhousie University, Halifax, Nova Scotia, Canada; 2) Biochemistry and Molecular Biology, Dalhousie University, Halifax, Canada. |
| 229A | High copy suppressors reveal links between the homologous proteins Sip3p and Ysp1p/YHR155w and mechanisms that maintain yeast membrane homeostasis. Gary Franke, Scott Erdman. Biology Dept., Syracuse University, Syracuse, NY. |
| 230B | Phosphatidylcholine transfer activity of yeast Sec14p is dispensable for its essential cellular function. Dana Tahotna, Roman Holic, Katarina Poloncova, Maria Simockova, Peter Griac. Dept Bioenergetics, Inst Animal Biochemistry & Genetics, Ivanka pri Dunaji, Slovakia. |
| 231C | Genetical Modification of Industrial Brewing Yeast by disrupting ILV2 gene and overexpression of a-amylase gene. Xiuping He, Feng Zhang, Zhaoyue Wang, Nan Liu, Borun Zhang. The Lab of Molecular Genetics and Breeding of Yeast, Institute of Microbiology, Chinese Academy of Science, Beijing 100080, P.R. China. |
| 232A | Regulation of triglyceride synthesis in Saccharomyces cerevisiae. Shilpa Jain, Adetoun Adeniji-Adele, Chris Consentino, Peter Oelkers. Bioscience and Biotechnology, Drexel University, Philadelphia, PA. |
| 233B | Amino Acid Permease Involvement in Volatile Anesthetic Response. Nikki R. Keasey, Ralph L. Keil. Biochemistry Dept, Penn State College of Medicine, Hershey, PA. |
| 234C | Quantitative microscopy of yeast subcellular structures. Heimo Wolinski1, Bettina Heise2, Erich Peter Klement2, Sepp D. Kohlwein1. 1) IMB Biochemistry, University of Graz, Graz, Austria; 2) Department of Knowledge-Based Mathematical Systems, Linz-Hagenberg, Johannes Kepler University Linz, Linz, Austria. |
| 235A | Coordinate control of multidrug resistance and sphingolipid biosynthesis. Soraya Riley1, Scott Moye-Rowley1,2. 1) Molecular Biology Program, University of Iowa, Iowa City, IA; 2) Department of Physiology and Biophysics University of Iowa Iowa City, IA 52242. |
| 236B | Metabolic-based breeding of bottom fermenting yeast for high sulfite production. Satoshi Yoshida1, Toshiko Minato1, Jun Imoto2, Rie Oouchi1, Tatsuji Ishiguro1, Emiko Shimada1, Satoru Mizutani1, Hiroyuki Yoshimoto1, Tomoyoshi Soga2. 1) Central Lab Frontier Technol, Kirin Brewery Co Ltd, Yokohama, Japan; 2) Institute for Advanced Biosciences, Keio University, Yamagata, Japan. |
| 237C | Mrs3, Mrs4 and Frataxin Provide Mitochondrial Iron Use. Yan Zhang, Elise R. Lyver, Andrew Dancis. Dept Medicine, Univ Pennsylvania, Philadelphia, PA. |
| 238A | Saccharomyces cerevisiae host transcriptional response to establishment of a membranous positive-strand RNA virus replication complex includes upregulation of ERG genes. Jason A. Ader, Benjamin J. Tiede, David B. Kushner. Department of Biology, Dickinson College, Carlisle, PA 17013. |
| 239B | Investigating the role of Sgs1 and Srs2 helicases in maintaining trinucleotide repeat stability in S. cerevisiae.. Ranjith P. Anand, Catherine H. Freudenreich. Department of Biology, Tufts University, Medford, MA 02155. |
| 240C | Recruitment of Gyp5p and Gyl1p, two members of the Ypt/Rab GAP family, at sites of polarized exocytosis. Marie-Hélène CUIF, Laurent CHESNEAU, Magali PRIGENT, Sophie DUPRE, Michel JACQUET. Institut de Microbiologie, Université Paris XI, Orsay, France. |
| 241A | The sphingolipid pathway regulates yeast sensitivity to cell wall synthesis inhibitors. Thomas Edlind, Santosh Katiyar. Dept Microbiol & Immunology, Drexel Univ Col Medicine, Philadelphia, PA. |
| 242B | Characterization of the Pdr5p ATPase and inhibition of its activity by clotrimazole. John Golin1, Zachary N. Kon2, Justin Martello1, Sherry Supernaavage1, Leanne Hanson1, Suresh V. Ambudkar3, Zuben Sauna3. 1) Dept Biol, Catholic Univ of America, Washington, DC; 2) University of Maryland School of Medicine, Baltimore, MD; 3) Laboratory of Cell Biology, NCI/NIH, Bethesda, MD. |
| 243C | iFRAP analysis of transcriptional complexes in Saccharomyces cerevisiae. Terry Haley, George Santangelo. Med. Biosci. & Bioinformatics, Univ. of Southern Mississippi, Hattiesburg, MS. |
| 244A | Identification and characterization of a novel class of Rad52 mutants that impairs its ability to form a repair center. Swee C. L. Hallwyl, Iben Plate, Xiaole Wang, Uffe H. Mortensen. Center for Microbial Biotechnology, Technical University of Denmark, Kgs. Lyngby, Denmark. |
| 245B | ABC transporters contribute to miltefosine resistance in PDR strains. Taylor Preston, Pamela Hanson. Department of Biology, Birmingham-Southern College, Birmingham, AL. |
| 246C | Analysis of the S. cerevisiae petite phenotype induced by deletion of GEF1. Angélica M López-Rodríguez, Alfonso Carabez-Trejo, Ricardo Miledi, Ataúlfo Martínez-Torres. Instituto de Neurobiología UNAM Campus Juriquilla Querétaro. Carretera Querétaro-SLP. Km 15, Juriquilla, Querétaro.C.P. 76230. |
| 247A | Stress-induced yeast ceramide-activated phosphatase can compensate for loss of amphiphysin-like activity. Paula C. McCourt, Joseph T. Nickels. Drexel Univ Col Medicine, Dept Biochemistry & Molec Biol, Philadelphia, PA. |
| 248B | PP2A regulates meiosis I. Jocelyn K. Nolt1, Lyndi M. Rice2, Joseph T. Nickels1. 1) Dept of Biochemistry & Molecular Biology, Drexel University College of Medicine, Philadelphia, PA; 2) Dept of Gene Expression and Regulation, Wistar Institute, Philadelphia, PA. |
| 249C | Defining the Membrane Topology of the Reductases Involved in Fatty Acid Elongation. Shilpi Paul, Teresa Dunn. Biochemistry & Molecular Bio., Uniformed Services University , Bethesda, MD. |
| 250A | Phosphatidylcholine turnorver is activated by an osmotic signal and is dependent on neuropathy targeted esterase 1 (Nte1), a B-type phospholipase in Saccharomyces cerevisiae. Robert Ramirez, Jeffrey Chan, Wipapat Kladwang, Maya Leiva, Kashif Abdullah. Biology Dept., San Francisco State Univ, San Francisco, CA. |
| 251B | Genetic analysis of SOD1 reveals novel relationships between oxidative stress and DNA replication/repair pathways in S. cerevisiae. Suveena Sharma, Lauren Kitchen, Wei-Chun Au, Carole D. Carter, Munira A. Basrai. Genetics Branch, CCR, National Cancer Institute, NIH, Bethesda, MD. |
| 252C | SIR2-independent chronological lifespan extension by dietary restriction in S. cerevisiae. Daniel L. Smith, Jeffrey S. Smith. Biochemistry & Mol. Genetics, University of Virginia, Charlottesville, VA. |
| 253A | Means to prevent the end: Mild stress induced multistress tolerance is caused by mild stress-specific mechanisms. Anna Zakrzewska, Gerco van Eikenhorst, Stanley Brul, Gertien Smits. Dept Molecular Biol, SILS, Univ Amsterdam, Amsterdam, Netherlands. |
| 254B | Genetic analysis of Saccharomyces cerevesiae Pdr5p/substrate interactions. Sherry L. Supernavage1, Leanne Hanson, Ph.D.1, Suneet Shukla, Ph.D.2, John E. Golin, Ph.D.1. 1) Biology Department, Catholic University, Washington, DC; 2) Laboratory of Cell Biology, National Cancer Institute, NIH, Bethesda, MD. |
| 255C | The putative drug:H+ antiporter Qdr2p is implicated in potassium uptake and provides a physiological advantage to quinidine stressed yeast cells. Sandra Tenreiro1, Rita C. Vargas1, Raúl Garcia-Salcedo2, Miguel C. Teixeira1, Alexandra R. Fernandes1, José Ramos2, Isabel Sá-Correia1. 1) CEBQ, Inst Superior Tecnico, Lisbon, Portugal; 2) Dept Microbiologia, Universidad de Córdoba, Córdoba, Spain. |
| 256A | Analysis of functional domains of the cell wall protein Flo11 from different yeast strains. Sreevardhini Venkatraman, Li Li, Lois Douglas, Yang Yang, Sungsu Lee, Anne Dranginis. Dept. Biological Sciences, St. John's University, Queens, NY. |
| 257B | Identification of amino-acid residues of the fifth transmembrane domain important for the substrate specificity of yeast plasma membrane Na+/H+ antiporters. Olga Zimmermannova, Martin Zavrel, Hana Sychrova. Membrane Transport, Inst. of Physiology, Prague 4 - Krc, Czech Republic. |
| 258C | Rrm3p-dependent replication is affected by different protein-DNA binding affinities at the HMR-E locus in Saccharomyces cerevisiae. Sarah D. Aubert, Virginia A. Zakian. Molecular Biology, Princeton University, Princeton, NJ. |
| 259A | The Saccharomyces cerevisiae helicase Rrm3p contributes to the replication of every yeast chromosome and is replication fork-associated throughout S-phase. Anna Azvolinsky1, Steve Dunaway2, Virginia Zakian1. 1) Molecular Biology, Princeton University, Princeton, NJ; 2) Drew University Madison, New Jersey. |
| 260B | The DNA binding activity of the S. cerevisiae MCM2-7 and MCM467 complexes. Matthew L. Bochman, Anthony Schwacha. Department of Biological Sciences, University of Pittsburgh, Pittsburgh, PA. |
| 261C | Multiple roles of CDK phosphorylation sites in preventing re-replication. Sangeet Honey, Bruce Futcher. Microbiology, Stony Brook University, Stony Brook, NY. |
| 262A | Interactions among DNA ligase I, the flap endonuclease and proliferating cell nuclear antigen in the expansion and contraction of CAG repeat tracts. Kenneth K Karanja, Eric W Refsland, Dennis M Livingston. Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, MN. |
| 263B | Modeling Mouse Cancer In Yeast. Xin Li, John Schimenti, Bik Tye. Molecular Biology and Genetics, Cornell University, Ithaca, NY. |
| 264C | The relationship between recombination, sister chromatid cohesion, and an alternative RFC complexes in Saccharomyces cerevisiae. oren parnas, Martin Kupiec. Molecular Microbiology , Tel Aviv University, Tel Aviv, Israel. |
| 265A | Nuclear and mitochondrial isoforms of the Pfh1p helicase are essential in fission yeast. Stefan Pinter, Virginia Zakian. Molecular Biology, Princeton University, Princeton, NJ. |
| 266B | Slx4 regulates DNA damage checkpoint-dependent phosphorylation of the BRCT domain protein Rtt107/Esc4. Tania M Roberts1, Michael S Kobor2,4, Suzanne A Bastin-Shanower3, Miki Ii3, Sonja A Horte4, Jennifer W Gin2, Andrew Emili5, Jasper Rine2, Steven J Brill3, Grant W Brown1. 1) Department of Biochemistry, University of Toronto, Toronto, Ontario, Canada M5S 3E1; 2) Department of Molecular and Cellular Biology, University of California, Berkeley, Berkeley, CA 94720; 3) Department of Molecular Biology and Biochemistry, Rutgers University, Piscataway, NJ 08854; 4) Centre for Molecular Medicine and Therapeutics, University of British Columbia, Vancouver, British Columbia, Canada V5Z 4H4; 5) Banting and Best Department of Medical Research, University of Toronto, Toronto, Ontario, Canada M5G 1L6. |
| 267C | The Cdc7-Dbf4 kinase phosphorylates Mcm4 through a docking site-mediated mechanism and promotes pre-initiation complex assembly. Yi-Jun Sheu, Bruce Stillman. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY. |
| 268A | Haploinsufficiency of Rad27 Affects Stability of Long CAG/CTG Repeats in S. cerevisiae. Jiahui Yang, Catherine H. Freudenreich. Deptartment of Biology, Tufts University, Medford, MA. |
| 269B | Cell cycle-dependent telomere association of Stn1p and Ten1p. Iris Cheung, Virgina A. Zakian. Dept of Molecular Biology, Princeton University, Princeton, NJ. |
| 270C | Saccharomyces telomerase regulation by Est1p and Est3p. Kathleen Daumer, Virginia Zakian. Molecular Biology, Princeton University, Princeton, NJ. |
| 271A | Dynamics and evolution of duplicated ORFs in the hemiascomycetous yeasts : Study of the DUP multigene family. Véronique Leh-Louis, Nicolas Jauniaux, Bénédicte Wirth, Serge Potier, Jean-Luc Souciet, Laurence Despons. GMGM UMR 7156 ULP/CNRS, Institut de Botanique, Strasbourg, France. |
| 272B | The Role of the Nuclear Periphery and Subtelomeric Structure in Telomere Position Effect and Telomere Length Regulation. Michelle A. Mondoux, Jillian S. Godfrey, Virginia A. Zakian. Department of Molecular Biology, Princeton University, Princeton, NJ. |
| 273C | Interacting partners of Esc1, a protein involved in silent chromatin positioning. Jenel Nixon, Marc Gartenberg. Pharmacology, Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, Graduate School of Biomedical Sciences, Piscataway, NJ. |
| 274A | TEL1/ATM and the Telomere Protein RIF1 Link Telomeres and the DNA Damage Response. Alo Ray, Kurt W. Runge. Dept. Molecular Genetics, Cleveland Clinic Foundation, Cleveland, OH. |
| 275B | Effects of telomere length on telomerase action in yeast. Michelle Sabourin, Virginia A. Zakian. Molecular Biology, Princeton University, Princeton, NJ. |
| 276C | Identification of telomerase RNA genes in yeast species with large telomeric repeats. Lubomir Tomaska, Stanislava Gunisova, Jozef Nosek. Departments of Genetics and Biochemistry, Comenius University, Faculty of Natural Sciences, Mlynska dolina, 842 15 Bratislava, Slovak republic. |
| 277A | Histone depletion causes altered centromere clustering and spindle structure in budding yeast. David C. Bouck, Kerry Bloom. Department of Biology, UNC Chapel Hill, Chapel Hill, NC. |
| 278B | Understanding histone function during chromosome segregation. Rebecca Danforth, Pinto Inés. Department of Biological Sciences, University of Arkansas, Fayetteville, AR. |
| 279C | Analyses of S. cerevisiae SPT4 provides insights into the mechanism of localization of Cse4p and maintenance of chromosome transmission fidelity. Steven A DeLuca1, Wei-Chun Au1, Jeanne Hanson1,2, Kenneth D Belanger2, Munira A Basrai1. 1) Genetics Branch, National Cancer Institute, Bethesda, MD; 2) Department of Biology, Colgate University, Hamilton, NY. |
| 280A | Involvement of the Hda1 deacetylase complex in centromere structure and function. Abeer Almutairi, Wesley Williamson, Marsha Rhoads, Inés Pinto. Department of Biological Sciences, University of Arkansas, Fayetteville, AR. |
| 281B | The mitotic spindle checkpoint monitors the essential condensin function in whole genome segregation. Vladimir Yong-Gonzalez1, Ilia Ouspenski2, Bi-Dar Wang2, Alexander Strunnikov2. 1) Molecular Biology Department, Sloan-Kettering Cancer Center, New York, NY, 10028; 2) Unit of chromosome structure and function, LGRD, NICHD, NIH. Bethesda, MD, 20892. |
| 282C | Microarray analysis of Ty1 induction in Saccharomyces cerevisiae. Caleb Cassidy-Amstutz, Jill B. Keeney. Biology, Juniata College, Huntingdon, PA. |
| 283A | Changes in retrotransposon organization in the Saccharomyces cerevisiae genome during natural and experimental evolution. Abram Gabriel1, Stephen Pratt2, Johannes Dapprich3, Mark Kunkel3, Joseph Schacherer2, Douglas Ruderfer2, Leonid Kruglyak2, Maitreya Dunham2. 1) Rutgers University, Piscataway, NJ; 2) Princeton University, Princeton, NJ; 3) Generation Biotech, Lawrenceville, NJ. |
| 284B | Host genes regulating high temperature transposition of Ty1 in Saccharomyces cerevisiae. Justin T. Neidig, Jill B. Keeney. Biology, Juniata College, Huntingdon, PA. |
| 285C | Mating-induced alteration of chromosome structure in Saccharomyces cerevisiae. Yuri Nishida, Bun-ichiro Ono. Front. Doct. Prog. in Sci. & Eng., Ritsumeikan Univ, Kusatsu, Japan. |
| 286A | Using synthetic biology to probe the sequence requirements for Ty1 transposition. Robert Yarrington, Sarah Richardson, Jef Boeke. Department of Molecular Biology and Genetics, The Johns Hopkins University School of Medicine, Baltimore, MD. |
| 287B | A genomic screen in Saccharomyces cerevisiae to identify gene deletions that affect Rad52 focus formation. David Alvaro1, Michael Lisby2, Rodney Rothstein1. 1) Dept of Genetics & Development, Columbia Univ., New York, NY; 2) Dept. of Genetics, Institute of Molecular Biology & Physiology, University of Copenhagen, Copenhagen, Denmark. |
| 288C | Explorations into the kinetochore localization of Rdh54. Rebecca Burgess1, Michael Lisby2, Rodney Rothstein3. 1) Biological Sciences, Columbia University, New York, NY., VI; 2) Institute of Molecular Biology & Physiology, University of Copenhagen, 1353 Denmark; 3) Genetics and Development, Columbia University, New York, NY. |
| 289A | Distribution of illegitimate recombination events in Kluyveromyces lactis. Andreas Kegel, Paula Martinez, Sidney Carter, Stefan Åström. Dept Developmental Biol, Stockholm Univ, Stockholm, Sweden. |
| 290B | Analysis of Genetic Instability in S. cerevisiae with Low Levels of DNA Polymerase. Anne M. Casper, Malgorzata Gawel, Thomas D. Petes. Department of Molecular Genetics & Microbiology, Duke University, Durham, NC 27710. |
| 291C | Molecular origin and fate of segmental duplications in the Saccharomyces cerevisiae genome. Payen Celia1, Koszul Romain2, Dujon Bernard1, Fischer Gilles1. 1) Institut Pasteur, Paris, FR; 2) MCB, Harvard University, USA. |
| 292A | Chromosomal dynamics in Saccharomyces cerevisiae : towards an identification of the molecular mechanisms involved in genic and segmental deletions. Emilie Fritsch, Yves Tourrette, Jean-Luc Souciet, Serge Potier, Jacky de Montigny. Laboratoire de Génétique Moléculaire, Génomique et Microbiologie UMR7156, 28 rue Goethe, 67083 Strasbourg, France. |
| 293B | The Rad51-K191R ATPase-defective mutant is impaired for presynaptic filament formation. Cindy W Fung2, Gary S Fortin4, Shaun E Peterson3, Lorraine S Symington1. 1) Dept. of Microbiology, Columbia University, New York, NY; 2) Integrated Program in Cellular, Molecular and Biophysics, Columbia University, New York, NY; 3) Graduated Program in Biological Sciences, Columbia University, New York, NY; 4) Rheogene, Inc. 2650 Eisenhower Avenue, Norristown, PA 19403. |
| 294C | Distinct domains of Atf1-Pcr1 heterodimer activate and repress hotspot meiotic recombination and osmoregulation in Schizosaccharomyces pombe. Jun Gao, Mari K. Davidson, Wayne P. Wahls. Department of Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences, 4301 West Markham Street(Slot 516), Little Rock, AR 72205. |
| 295A | Mdt1 functions as a novel facilitator of recombinational repair of drug-induced DNA double-strand breaks and telomerase-independent telomere elongation. Brietta Pike, Jörg Heierhorst. Molecular Genetics Unit, St. Vincent's Institute, Melbourne, Victoria, Australia. |
| 296B | Dynamics of Recombination and Improved Assays for Screening in Homothallic Switching. Peter Houston, James Broach. Deptartment of Molecular Biology, Princeton University, Princeton, NJ. |
| 297C | ZMM proteins antagonize the anti-crossover activity of the Sgs1 helicase during meiotic recombination in Saccharomyces cerevisiae. Lea Jessop1, Beth Rockmill2, Shirleen Roeder2,3, Michael Lichten1. 1) Laboratory of Biochemistry, NCI, Bethesda, MD; 2) Howard Hughes Medical Institute Department of Molecular, Cellular and Developmental Biology Yale University New Yaven, CN; 3) Deparment of Genetics Yale University New Haven, CN. |
| 298A | The Overall Distribution of Crossovers in Humans and Yeast is Alike. Arnold Barton, Mike Pekosz, Rohini Kurvathi, David Kaback. Dept Microbiol/Molecular Gen, UMDNJ-New Jersey Medical Sch, Newark, NJ. |
| 299B | Instability of CAG/CTG trinucleotide repeats in srs2 and sgs1 mutants, in S. cerevisiae. Alix Kerrest, Guy-Franck Richard, Bernard Dujon. Genomes et Genetique, Institut Pasteur, Paris, France. |
| 300C | A Physical Assay System for Recombination-Dependent Replication. Vanessa A Marrero1, Lorraine S Symington2. 1) Department of Genetics and Development, Columbia University, New York, NY; 2) Department of Microbiology, Columbia University, New York, NY. |
| 301A | The Role of Rad55 and Rad57 in Homologous Recombination. Amy M. Mozlin, Lorraine S. Symington. Department of Microbiology, Columbia University Medical Center, New York, NY. |
| 302B | Regulation of the meiosis-specific Mek1 kinase in yeast. Hengyao Niu, Emily Job, Nancy M. Hollingsworth. Dept Biochemistry & Cell Biol, SUNY, Stony Brook, NY. |
| 303C | Identifying gene deletions affecting recombination in Saccharomyces cerevisiae by the formation of cyh2R homozygosity and cycloheximide resistance. Steven Pierce1, David Alvaro2, Rodney Rothstein2. 1) Dept of Biological Sciences, Columbia University, New York, NY; 2) Dept of Genetics and Development, Columbia University Medical Center, New York, NY. |
| 304A | A meiotic barrier to sister chromatid repair does not require the presence of a homolog and is ineffective in preventing DMC1-dependent repair. Tracy L. Robinson, Julie Romero, Nancy M. Hollingsworth. Biochemistry and Cell Biology, SUNY Stony Brook, Stony Brook, NY. |
| 305B | Suppression of complex and recurring translocations by Sgs1 helicase. Kristina Schmidt1, Joann Wu2, Richard Kolodner2. 1) Dept Biol, Univ South Florida, Tampa, FL; 2) Ludwig Institute for Cancer Research, UCSD, La Jolla, CA. |
| 306C | Recombination Dependent Replication Can Occur by a Template Switching Mechanism. Catherine E Smith1, Lorraine S Symington2. 1) Biological Sciences, Columbia University, New York, NY; 2) Microbiology, Columbia University, New York, NY. |
| 307A | DSB-dependent phosphorylation of the meiosis-specific chromosome core protein Hop1. Lihong Wan1, Tatiana Garcia-Muse2, Simon Boulton2, Nancy M. Hollingsworth1. 1) Dept Biochemistry & Cell Biol, SUNY Stony Brook, Stony Brook, NY; 2) Cancer Research UK, Clare Hall Labs. |
| 308B | The importance of ring-structure formation for nuclear transport of Rad52 in Saccharomyces cerevisiae. Line Albertsen, Iben Plate, Uffe Mortensen. Center for Microbial Biotechn., DTU-Biocentrum, Lyngby, Lyngby, Denmark. |
| 309C | Regulation of the ribonuleotide reductase inhibitor Sml1 in response to DNA damage. Bethany Andreson1, Bilyana Georgieva2, Rodney Rothstein2. 1) Dept of Biological Sciences, Columbia University, New York, NY; 2) Dept of Genetics and Development, Columbia University Medical Center, New York, NY. |
| 310A | Overlapping function of TRM2/RNC1 and EXO1 in DNA double strand break repair in Saccharomyces cerevisiae. Sibgat A. Choudhury, Benyam Asefa, Paul Kauler, Terry Y.K. Chow. Oncology, Faculty of Medicine, MUHC/McGill University , Montreal, Quebec, Canada. |
| 311B | A novel palindrome revision process occurs via a high fidelity non-canonical end joining pathway. Atina Cote1,2, Alison Rattray3, Susanna Lewis1,2. 1) Genetics & Genomic Biology, Hospital for Sick Children, Toronto, ON, Canada; 2) Molecular and Medical Genetics, University of Toronto, ON, Canada; 3) Gene Regulation and Chromosome Biology Laboratory NCI Frederick. MD, USA. |
| 312C | A Novel MLH1 Allele Preferentially Affects the Repair of Template Strand Loops during DNA Replication. Naz Erdeniz, Michael Liskay. Department of Molecular & Medical Genetics, Oregon Health Sciences University, Portland, OR. |
| 313A | Characterization of pathogenic human MSH2 missense mutations using yeast as a model system. Alison Gammie, Naz Erdeniz, Julia Beaver, Afshan Nanji, Barbara Devlin, Mark Rose. Dept Molecular Biol, Princeton Univ, Princeton, NJ. |
| 314B | Role of ubiquitination in regulation of ribonucleotide reductase inhibitor, Sml1. Amitabha Gupta1, Bethany Andreson2, Bilyana Georgieva3, Rodney Rothstein3. 1) Dept of Cell., Mol., Biophys Stud.,; 2) Dept of Bio. Sci.,; 3) Dept. Of Genetics and Dev., Columbia Univ Med Center, New York, NY. |
| 315C | Role of Clu1p in mitochondrial genome stability and morphology in budding yeast. Christine E. Hochmuth, Crystal R. Allen, Rey A. Sia. Biological Sciences, SUNY Brockport, Brockport, NY. |
| 316A | The role of zinc homeostasis in minisatellite stability. Maire Kate Kelly, David T. Kirkpatrick. Department of Genetics, Cell Biology and Development, University of Minnesota, 6-160 Jackson Hall, 321 Church St SE, Minneapolis, MN 55455. |
| 317B | The role of chromatin remodelling during nucleotide excision repair in Saccharomyces cerevisiae. Rhian Kiely, Peter J. McHugh. Cancer Research UK, WIMM, University of Oxford, Oxford, Oxfordshire, United Kingdom. |
| 318C | Factors that are required for MMEJ indicate MMEJ is a distinct mechanism of DSB repair. Kihoon Lee, Sang Eun Lee. Molecular Medicine, UTHSCSA, San Antonio, TX. |
| 319A | Establishment of a system to analyze the effects of membrane lipid peroxidation on genome stability in Saccharomyces cerevisiae. Nicholas R. Pannunzio, John Termini, Adam M. Bailis. Division of Molecular Biology, City of Hope, Duarte, CA. |
| 320B | Analysis of a novel mitochondrial helicase that protects the yeast mitochondrial genome from ultraviolet light induced damage. Naina Phadnis, Elaine Sia. Dept. of Biology, University of Rochester, Rochester, NY. |
| 321C | Base excision repair proteins involved in mitochondrial DNA stability and a reporter system to determine point mution rates within mitochondrial DNA. Leah A. Pogorzala, Elaine A. Sia. Biology, University of Rochester, Rochester, NY. |
| 322A | Mechanism and genetic requirements of palindromic gene amplification in S. cerevisiae. Alison Rattray, Anne Welcker, Brenda Shafer, Jeffrey Strathern. Gene Reg/Chromosome Biol Lab, NCI/CCR/FCRDC, Frederick, MD. |
| 323B | Recombinational repair of DNA interstrand crosslinks. Wilma Saffran, Charles W. Senior, Varsha Dabiesingh, Lamiaa Seyam, Pooja Agarkar, Amita Gupta, Kenneth Reyes. Dept Chemistry/Biochemistry, Queens Col, CUNY, Flushing, NY. |
| 324C | Analysis of mutations induced by carbon ions in the budding yeast Saccharomyces cerevisiae. Kikuo Shimizu1, Youichirou Matuo2, Shigehiro Nishijima2, Yoshihiro Hase3, Ayako Sakamoto3, Atsushi Tanaka3. 1) Radioisotope Research Center, Osaka University, Suita, Osaka 565-0871, Japan; 2) Graduate School of Engineering, Osaka University, Suita, Osaka 565-0871, Japan; 3) Radiation-Applied Biology Division, Quantum Beam Science Directorate, Japan Atomic Energy Agency (JAEA), Takasaki, Gunma 370-1292, Japan. |
| 325A | The role of Abf2p in mitochondrial genome stability. Rey Sia, Stephanie Carroll, Christine Hochmuth. Dept. of Biological Sciences, SUNY at Brockport, Brockport, NY. |
| 326B | Histone H3 plays diverse roles in post-replication repair and nucleotide excision repair of UV-damaged DNA. Jeffrey S. Thompson, Lindsey J. Bostelman, Andrew M. Keller, Arzu Arat. Department of Biology, Denison University, Granville, OH. |
| 327C | A Quantitative Method for In Vivo Footprinting Reveals a Non-Nucleosomal Putative Protein at an Activator Binding Site. Gene O. Bryant, Dan Spagna, Mark Ptashne. Program in Molecular Biology, Sloan-Kettering Inst., New York, NY. |
| 328A | Conserved regions within the N-terminus of Sir1 define a new interaction required for Sir1-silencer recognition in Saccharomyces cerevisiae. John Danzer, Zhonggang Hou, Melissa Bose, Catherine Fox. Dept of Biomolecular Chemistry, University of Wisconsin, Madison, WI. |
| 329B | Characterization of the PHD fingers of Msc1, the fission yeast homolog of RBP2 and PLU-1. Barbara Dul, Nancy Walworth. UMDNJ-RWJMS Cellular and Mol. Pharmacology, 675 Hoes Lane, Piscataway, NJ. |
| 330C | The beginning and the end of sister chromatid cohesion; Pds5p provides a connection. Daniel Noble1, Margaret Kenna2, Melissa Dix1, Robert Skibbens2, Vincent Guacci1. 1) Embryology, Carnegie Institution, Baltimore, MD; 2) Biological Sciences, Lehigh University, Bethlehem, PA. |
| 331A | Genome-wide analysis of nucleosome positioning and chromatin dynamics in Saccharomyces cerevisiae. William Lee1,2, Ronald W. Davis2, Corey Nislow2, Guri Giaever2. 1) Deptartment of Genetics, Stanford University, Stanford, CA; 2) Stanford Genome Technology Center, Palo Alto, CA. |
| 332B | Chromosomal location of Lg-FLO1 gene and relationship between Lg-FLO1 gene and yeast flocculation. Tomoo Ogata, Mami Izumikawa, Katsunori Kono, Kazunori Shibata. Brewing Res & Dev Lab, Asahi Breweries, Ltd, Ibaraki, Japan. |
| 333C | Regulation of nucleolar contraction and rDNA condensation by target of rapamycin (TOR). Chi Kwan Tsang, Steven X. F. Zheng. Pharmacology, UMDNJ-RWJ Medical School, Piscataway, NJ. |
| 334A | Nucleolar transcription levels regulate cell cycle dynamics of condensin distribution in the yeast genome. Bi-Dar Wang1, Pavel Butylin1, Munira Basrai2, Michael Lichten3, Alexander Strunnikov1. 1) Laboratory of Gene Regulation and Development, NICHD, NIH, Bethesda, MD; 2) Genetic Branch, Center for Cancer Research, NCI, NIH, Bethesda, MD; 3) Laboratory of Biochemistry, Center for Cancer Research, NCI, NIH, Bethesda, MD. |
| 335B | Nuclear Functions for the Spindle Pole Body Component Mps3. Jennifer M Bupp, Karin Zueckert-Gaudenz, Chris Seidel, Sue Jaspersen. The Stowers Institute for Medical Research, Kansas City, MO. |
| 336C | Interaction of yeast plasmid segregation proteins Rep1 and Rep2 with SUMO and the SUMO-specific ligase Siz2. Jordan B. Pinder, Joyce S.K. Chew, Jeremy J.R. Benjamin, Nisa Renault, Kona Williams, Melanie J. Dobson. Department of Biochemistry and Molecular Biology, Dalhousie University, Halifax, NS, Canada B3H 1X5. |
| 337A | A Requirement for tDNA in the Cohesion of Neighboring Silent Chromatin. Rudra N Dubey, Marc R Gartenberg. Pharmacology, UMDNJ, 675 Hoese Lane, Piscataway, NJ 08854. |
| 338B | The Pif1 and Rrm3 DNA helicases are required for mitochondrial genomic stability. Xin Cheng, Yong Qin, Andreas S. Ivessa. Department of Cell Biol. and Molec. Medicine, University of Medicine and Dentistry NJ, Newark, NJ. |
| 339C | A scheme to induce and selectively maintain specific N+1 disomes. Julie Kudrna, Daniel Pauw, BreAnna Kinghorn, Anders Peck, Justin Platon, Kirk Anders. Dept of Biology, Gonzaga University, Spokane, WA. |
| 340A | In Candida albicans, survival is often based on loss of an entire chromosome which carries multiple redundant negative regulatory genes. Elena Rustchenko1, M. Anaul Kabir1, Ausaf Ahmad1, Jay R. Greenberg1, Ying-Kai Wang2. 1) Dept Biochemistry & Biophysics, Univ Rochester Medical Sch, Rochester, NY, 14642, USA; 2) Bristol-Myers Squibb Company,Wallingford, CT, 06492, USA. |
| 341B | Reduced cohesin binding around centromere is responsible for increased mis-segregation of mini-chromosome in Saccharomyces cerevisiae. Kazuo Yamagishi1, Minetaka Sugiyama1, Yuki Katou2, Katsuhiko Shirahige2, Yoshinobu Kaneko1, Satoshi Harashima1. 1) Biotech., Osaka Univ., Osaka, Japan; 2) Cent. Bio. Resource Info., Tokyo Inst. Tech., Yokohama., Japan. |
| 342C | Characterization of Rkr1, a nuclear RING-domain protein with functional connections to chromatin modification. Mary A. Braun, Rebecca E. Gonda, Karen M. Arndt. Department of Biological Sciences, University of Pittsburgh, Pittsburgh, PA. |
| 343A | FKH1-dependent conversion of replication origins to SIR1-independent silencers at HMRa. Laurieann Casey1, Erin E. Patterson2, Ulrika Müller1, Catherine A. Fox1,2. 1) Department of Biomolecular Chemistry; 2) Laboratory of Genetics, University of Wisconsin School of Medicine and Public Health, Madison,WI. |
| 344B | At the crossroads of RNA and chromatin. Christie S Chang, Astrid Clarke, Lorraine Pillus. Division of Biological Sciences, University of California San Diego, La Jolla, CA. |
| 345C | Investigation of transcription initiation from cryptic promoters in Saccharomyces cerevisiae. Vanessa Cheung1, Gordon Chua2, Timothy R Hughes2, Fred Winston1. 1) Dept of Genetics, Harvard Medical School, 77 Ave Louis Pasteur, Boston, MA, 02115; 2) Banting and Best Dept of Medical Research, Univ of Toronto, 160 College St, Toronto, ON, M5S 3E1 Canada. |
| 346A | Regulation of histone H3 lysine 36 methylation during transcription in S. cerevisiae. Yaya Chu1, Ann Sutton2, Rolf Sternglanz2, Greg Prelich1. 1) Molecular Genetics, AECOM, Bronx, NY; 2) Biochemistry and Cell Biology, Stony Brook University, NY. |
| 347B | The Evolution of Silencing Mechanisms in Saccharomyces. Jennifer Gallagher, Oliver Zill, Leonid Teytelman, Joshua Babiarz, Jasper Rine. Molecular and Cell Biology, 522 Barker Hall University California, Berkeley, Berkeley, CA 94720-3202. |
| 348C | Screen for Histone H3 mutants that de-repress the Saccharomyces cerevisiae CHA1 gene under non-inducing conditions. Qiye He, Randall Morse. Dept Biomedical Sci, SUNY, Wadsworth Ctr, Albany, NY. |
| 349A | Interaction of chromatin structure and Reg1-mediated pathways in glucose repression. Juan J. Infante, G. Lynn Law, Rhiannon Biddick, Christine Tachibana, Kenneth M. Dombek, Elton T. Young. Department of Biochemistry, University of Washington. Seattle, WA. |
| 350B | Plant-pathogenic bacterial type III effector XopD, a SUMO protease, affects expression of SNF2-regulated genes in yeast and causes growth defects. Jung-Gun Kim, Mary Beth Mudgett. Department of Biological Sciences, Stanford University, Stanford, CA 94305. |
| 351C | Functional links between silent chromatin and beta-1,3-glucanosyltransferase activity. Melissa R. Krick, Sandra N. Garcia, Lorraine Pillus. Division of Biological Sciences, UC San Diego, La Jolla, CA. |
| 352A | Adenine and thymine nucleotides are major players in the structure of a gene lock and a gene key in eukaryots. Bogdan Kurchii. Institute of Plant Physiology and Genetics, 31/17 Vasylkivska, 03022 Kyiv, Ukraine. |
| 353B | Sir2 regulates histone modifications and RNA polymerase II-mediated transcription at the ribosomal DNA locus in Saccharomyces cerevisiae. Chonghua Li, John E Mueller, Mary Bryk. Biochemistry and Biophysics, Texas A&M University, College Station, TX. |
| 354C | MCM Proteins Are Involved in Transcriptional Silencing in S. cerevisiae. Ivan Liachko, Bik Tye. Dept Molec Biol & Genetics, Cornell Univ, Ithaca, NY. |
| 355A | Silencing vs. Gene Specific Repression: Swapping the specificity of the Sir2 and Hst1 Histone Deacetylases. Janet Mead, Ron McCord, Laura Youngster, Harmeet Bassi, Andrew Vershon. Waksman Inst, Rutgers Univ, Piscataway, NJ. |
| 356B | Histone H3 mutations that increase silencing in the ribosomal DNA in yeast. Anne Norris, Jeong Park, Shan Guan, Joel Bader, Jef Boeke. HiT Center, Johns Hopkins SOM, Baltimore, MD. |
| 357C | Active site characterization of histone acetyltransferase 1 (Hat1p). Mark Parthun, Erica Mersfelder. Dept Molecular and Cellular Biochemistry, Ohio State University, Columbus, OH. |
| 358A | Antagonism between the SWI/SNF and ISW2 nucleosome remodeling complexes regulate RNR3 by generating distinct chromatin states. Joseph Reese, Zhengjian Zhang, Raguvir Tomar, Hesheng Zhang. Dept Biochem & Molec Biol, Penn State Univ, State College, PA. |
| 359B | Suppressors of Sir2-induced lethality in yeast. Hannah Stubbs, Scott G. Holmes. Molecular Biology, Wesleyan University, Middletown, CT. |
| 360C | Post-transcriptional de-repression of FLO11 in chromatin compromised mutant cells upon amino acid starvation. Oliver Valerius1, Claudia Fischer2, Heike Rupprecht1, Sven Krappman1, Gerhard Braus1. 1) Dept Molec Microbiol & Gen, Georg-August Univ, Goettingen, Germany; 2) DSMZ-German Collection of Microorganisms and Cell Cultures, Braunschweig, Germany. |
| 361A | Analysis of the chromatin structure of individual ribosomal DNA repeats in S. cerevisiae. Kelly M Williamson, John E Mueller, Mary Bryk. Biochemistry and Biophysics, Texas A&M University, College Station, TX. |
| 362B | Mechanism of the Long Range Anti-silencing Function of Targeted Histone Acetyltransferases in Yeast. Qun Yu, Joseph Sandmeier, Hengping Xu, Yanfei Zou, Xin Bi. Department of Biology, University of Rochester, Rochester, NY14627. |
| 363C | Structural Analyses of Sum1-1p-dependent Transcriptionally Silent Chromatin in Saccharomyces cerevisiae. Qun Yu, Susan Elizondo, Xin Bi. Department of Biology, University of Rochester, Rochester, NY14627. |
| 364A | Chromatin architecture regulates transcription factor requirements in yeast. Hesheng Zhang, Joseph Reese. Penn State Univ, Department of Biochemistry and Molecular Biology, University Park, PA 16802. |
| 365B | Position effect on silencer function in Saccharomyces cerevisiae. Yanfei Zou1, Qun Yu1, Ya-Hui Chiu2, Xin Bi1. 1) Department of Bilogy, University of Rochester, Rochester, NY14627; 2) Center for Aging and Developmental Biology, University of Rochester Medical Center, Rochester, NY 14642. |
| 366C | Asymmetric positioning of nucleosomes and directional establishment of transcriptionally silent chromatin by Saccharomyces cerevisiae silencers. Yanfei Zou, Qun Yu, Xin Bi. Department of Bilogy, University of Rochester, Rochester, NY14627. |
| 367A | Interactions of the Paf1 complex. Donovan Rigirozzi, L.P. Wegrzyn, Joan L. Betz. Dept. Biology, Regis University, Denver, CO. |
| 368B | The general stress response and FLO11 are co-regulators of invasive growth. Eran Blachinsky, David Engelberg. Biological Chemistry, Hebrew University of Jerusalem, Jerusalem, Israel. |
| 369C | Maf1 is involved in coupling carbon metabolism to RNA Polymerase III transcription. Malgorzata Ciesla1, Joanna Towpik1, Danuta Oficjalska1, 2, Karol Balicki1, Wieslaw Smagowicz1, Olivier Lefebvre2, Magdalena Boguta1. 1) Department of Genetics, Institute of Biochemistry and Biophysics,PAS, Warsaw, Poland; 2) Laboratoire de Transcription des gènes, Service de Biochimie et de Génétique Moléculaire, CEA/Saclay, Gif-sur-Yvette Cedex, France. |
| 370A | Phosphorylation sites in Msn2 that target it for Srb10/11-dependent degradation. Sohini Bose, Soo Hwang, Richard Zitomer. Dept. of Biological Sciences, University at Albany/SUNY, Albany, NY, 12222 USA. |
| 371B | Transcriptional regulation of SPI1 gene at the post-diauxic shift. Characterization of tryptophan, Rsp5p and flavodoxin-like proteins as potential regulators. Fernando Cardona1,2, Sylvie Friant3, Marcel.lí del Olmo1, Agustín Aranda1,2. 1) Departamento de Bioquímica y Biología Molecular, Universidad de Valencia, Burjassot , Valencia, Spain; 2) Deparmento de Biotecnología, Instituto de Agroquímica y Tecnología de Alimentos, CSIC, Valencia, Spain; 3) Institut de Physiologie et Chimie Biologique, CNRS-Université Louis Pasteur, Strasbourg, France. |
| 372C | Roles of cis- and trans- changes in the regulatory evolution of genes in gluconeogenesis. Ya-Wen Chang, Ning Yu, Fu-Guo Robert Liu, Wen-Hsiung Li. Dept Ecology & Evolution, Univ Chicago, Chicago, IL. |
| 373A | Silencing without Sir2. Chia-Ching Chou, Marc R Gartenberg. Pharmacology, Robert Wood Johnson Medical School, Graduate School of Biomedical Sciences, University of Medicine and Dentistry of New Jersey, Piscataway, NJ. |
| 374B | Trehalose affects the transcriptional activity of yeast heat shock transcription factor. Laura K. Conlin, Hillary C.M. Nelson. Department of Biophysics and Biochemistry, The University of Pennsylvania School of Medicine, Philadelphia, PA. |
| 375C | The synthesis of rRNA by RNA polymerase II in S. cerevisiae. Gunisha Sagar, Matthew Haymowicz, Heather Conrad-Webb. Dept Biol, Texas Woman's Univ, Denton, TX. |
| 376A | Role of GATA factors in carbon-responsive UGA4 gene expression in Saccharomyces cerevisiae. Mariana Bermudez Moretti, Carlos Luzzani, Guillermo Risso, Susana Correa Garcia. Quimica Biol, Fac Ciencias, Univ Buenos Aires, Pcia Buenos Aires, Argentina. |
| 377B | AICAR-SAICAR : small molecules big effects. Benoit Pinson, Bertrand Daignan-Fornier. Inst Biochem & Genetique Cell, CNRS UMR 5095, Bordeaux, France. |
| 378C | Regulation of chromatin remodeling complex RSC by PLC1 and inositol polyphosphates. Parima Desai, Ales Vancura. Dept. of Biological Sciences, St. Johns University, Queens, NY. |
| 379A | Characterization of upstream activating sequence function. Krista Dobi, Fred Winston. Dept Genetics, Harvard Medical Sch, Boston, MA. |
| 380B | Characterizing Sterol Defect Suppressors Uncovers a Novel Transcriptional Signaling Pathway Regulating Zymosterol Biosynthesis. Christina Gallo, Joseph Nickels. Dept Biochemistry & Molec Biol, Drexel Univ Col Medicine, Philadelphia, PA. |
| 381C | Protein factors bound at NCR-sensitive promoters. Prelude to a detailed analysis. Isabelle Georis, Evelyne Dubois. Institut de Recherches Microbiologiques J.-M. Wiame, Laboratoire de Microbiologie de l'ULB, Bruxelles, Belgium. |
| 382A | Ras-dependent acetylation and heat shock-dependent deacetylation of histones H3 and H4 on the HSP104 promoter of S.cerevisiae. Melanie R. Grably, Dana Laor, David Engelberg. Biological Chemistry , Hebrew University, Jerusalem, Israel. |
| 383B | PLC1 is essential for the recruitment of SAGA at the osmoinducible promoters. Nilanjan Guha, Ales Vancura. Dept. of Biological Sciences, St.Johns University, Queens, NY. |
| 384C | Compartment-specific synthesis of phospholipids serves as a regulatory signal for expression of multidrug resistance genes. Kailash Gulshan, W. Scott Moye-Rowley. Deptt. of Physiology & Biophysics, Univ of Iowa, Iowa City, IA. |
| 385A | The role of Hap1 and other factors in the S. cerevisiae transcriptional response to hypoxia. Mark Hickman, Fred Winston. Department of Genetics, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, MA 02115. |
| 386B | The SAGA complex component Ada2 binds phosphatidylinositolphosphates and shows genetic interactions with the PtdIns(3)P 5-kinase Fab1. Stephen M.T. Hoke, Gaoyang Liang, Julie Genereaux, A. Irina Mutiu, Christopher J. Brandl. Department of Biochemistry, University of Western Ontario, London, Ontario, Canada, N6A 5C1. |
| 387C | A genetic screen for novel regulators of rDNA transcription in Saccharomyces cerevisiae. Robert D. Hontz1, Sarah L. French2, Ann L. Beyer2, Jeffrey S. Smith1. 1) Biochemistry and Mol. Genetics, University of Virginia, Charlottesville, VA; 2) Microbiology, University of Virginia, Charlottesville, VA. |
| 388A | Quantitative analysis of in vivo initiator selection by yeast RNA polymerase II supports a scanning model. Jason N. Kuehner, David A. Brow. Dept. of Biomolecular Chemistry, University of Wisconsin School of Medicine and Public Health, 1300 University Ave., Madison, WI 53706, USA. |
| 389B | Oxidative stress-activated zinc cluster protein Stb5 has dual activator/repressor functions required for pentose phosphate pathway regulation and NADPH production. Marc Larochelle1, Simon Drouin4, Francois Robert4, Bernard Turcotte1,2,3. 1) Medicine, McGill University, Montreal, Quebec, Canada; 2) Biochemistry, McGill University, Montreal, Quebec, Canada; 3) Microbiology and Immunology, McGill University, Montreal, Quebec, Canada; 4) Institut de recherche clinique de Montreal, Montreal, Quebec, Canada. |
| 390C | Identification of a mitochondrial uncoupling protein in mitochondrial transcription of Saccharomyces cerevisiae. ChangWoo Lee1, Si Ae Hwang1, Ji-Hoon Lee2, Hyun-Jung Kim2, Tae-Jin Kim2, Jae-Hwan Choi2, Ji-Hyun Kim2, Moon-Sook Kim2, Sei-Heon Jang1. 1) Dept. of Genetic Engineering, Daegu University, Gyeongsan 712-714, Korea; 2) Daegu Science High School, Daegu 706-852, Korea. |
| 391A | Stb3, a putative RRPE regulator. Dritan Liko1, Matthew G. Slattery2, Bruce N. Bagley2, Warren Heideman1,2. 1) Biomolecular Chemistry, University of Wisconsin, Madison, WI; 2) School of Pharmacy, University of Wisconsin, Madison, WI. |
| 392B | Ab initio prediction of DNA-binding sites of transcription factors. L. Angela Liu, Joel Bader. Department of Biomedical Engineering and High-Throughput Biology Center, Johns Hopkins University, 3400 N Charles St, Baltimore, MD 21218. |
| 393C | Genetic and biochemical studies of S. cerevisiae RNAPII and TFIIF function during transcription initiation and elongation. Robert C. Majovski, Denys A. Khaperskyy, Michelle L. Ammerman, Alfred S. Ponticelli. Department of Biochemistry, University at Buffalo, School of Medicine and Biomedical Sciences, Buffalo, New York, 14214, USA. |
| 394A | NC2 is important for transient trasncriptional control of heat shock genes upon heat shock. Patrick Masson1, Nadia Ammann1, Elisa Leimgruber1, Sandrine Creton2, Nicole Paquet1, Martine A. Collart1. 1) Microbiology and Molecular Med, Centre medical universitaire, GENEVA, Switzerland; 2) Max Planck Institute of Biochemistry Department of Molecular Cell Biology Am Klopferspitz 18 82152 Martinsried Germany. |
| 395B | Pdc2 coordinates expression of the THI regulon in the yeast Saccharomyces cerevisiae. Dominik Mojzita, Stefan Hohmann. Dept CMB/Microbiology, Gothenburg Univ, Gothenburg, SWEDEN. |
| 396C | Mating defects in C. glabrata: pheromone response and silencing defects. Heloise M.E. Muller, Bernard Dujon, Cecile Fairhead. Genomes et genetique, Institut Pasteur, Paris, France. |
| 397A | Identification of functionally important residues within the PI3K domain of Tra1. A. Irina Mutiu, Julie Genereaux, Carol Hannam, Stephen M.T. Hoke, Christopher J. Brandl. Biochemistry, University of Western Ontario, London, Ontario, Canada. |
| 398B | The Sen1 helicase is required for transcription termination on mRNA-encoding genes. Eduard C. NEDEA, Daniel XIA, Bernhard Suter, Jeffrey Fillingham, Jack Greenblatt. Dept. of Molecular and Medical Genetics, University of Toronto, Centre for Cellular and Biomolecular Research, Toronto, ON, Canada. |
| 399C | Novel target genes of yeast transcription factor Pho4 identified by ChIP on Chip analysis. Masafumi Nishizawa1, Tae Komai2, Yuki Katou3, Katsuhiko Shirahige3, Takehiko Itoh4, Akio Toh-e5. 1) Dept. Microbiol. & Immunol., Keio Univ. School of Medicine, Tokyo, Japan; 2) Faculty of Science, Japan Women’s Univ; 3) Ctr. Biol. Res. & Info., Tokyo Inst. Tech. Grad. Sch. of Biosci. & Biotech; 4) Mitsubishi Research Inst. Inc; 5) Dept. Biol. Sci., Univ. of Tokyo Grad. Sch. of Science. |
| 400A | Characterization of the jumonji domain in yeast. Niklas Nordberg1, Susanna Tronnersjö1,2, Christine Hanefalk2, Darius Balciunas3, Guo-Zhen Hu2, Hans Ronne1,2. 1) Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden; 2) Department of Plant Biology and Forest Genetics, SLU, Uppsala, Sweden; 3) Department of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, USA. |
| 401B | Transcription factor binding sites in the Saccharomyces Genome Database (SGD). Rose Oughtred1, Karen R. Christie2, Rama Balakrishnan2, Ben Hitz2, Maria C. Costanzo2, Stacia R. Engel2, Dianna G. Fisk2, Jodi E. Hirschman2, Eurie L. Hong2, Mike S. Livstone1, Rob Nash2, Marek S. Skrzypek2, Chandra L. Theesfeld2, Gail Binkley2, Qing Dong2, Anand Sethuraman2, Shuai Weng2, Kara Dolinski1, David Botstein1, J. Michael Cherry2. 1) Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ 08544, U.S.A; 2) Department of Genetics, Stanford University, 300 Pasteur Drive, Stanford, CA 94305, U.S.A. |
| 402C | Regulation of diverse functions of Rap1 in Saccharomyces cerevisae. Bilge Ozaydin, Leonid Teytelman, Jasper Rine. Dept Molecular & Cell Biol, Univ California, Berkeley, Berkeley, CA. |
| 403A | Transcriptional activation by human Nup98 in Saccharomyces cerevisiae. Maneeshi Prasad, George Santangelo. Med. BioSci. & Bioinformatics, Univ. of Southern Mississippi, Hattiesburg, MS. |
| 404B | Up, Down and Sideways: Roles for Transcription-Factor Kar4p in the Yeast Pheromone Response. Ron Lahav, Alison Gammie, Saeed Tavazoie, Mark Rose. Dept Molecular Biology, Princeton University, Princeton, NJ. |
| 405C | In vivo Adr1 promoter binding studied with a hormone inducible system. Riccardo L. Rossi, Elton T. Young. Department of Biochemistry, University of Washington, Box 357350, Seattle WA 98195. |
| 406A | Analysis of genetic and biochemical interactions of Rpb4/ Rpb7: The ‘Been there-done that’ sub-complex of yeast RNA polII. Parag Sadhale1, Jiyoti Verma1, Bindu Balakrishnan1, Vinaya Sampath2. 1) Microbiology & Cell Biology, Indian Institute of Science, Bangalore,INDIA; 2) SUNY at Stony Brook, New York, USA. |
| 407B | Negative regulation of transcription factor Pdr3p activity by the Hsp70 protein Ssa1p. Puja Shahi, W. Scott Moye-Rowley. Physiology/Biophysics, University of Iowa, Iowa City, IA. |
| 408C | A chemical genomics screen to identify targets of the Snf1 protein kinase. Margaret K. Shirra1, Rhonda R. McCartney2, Kevan M. Shokat3, Martin C. Schmidt2, Karen M. Arndt1. 1) University of Pittsburgh, Pittsburgh, PA 15260; 2) University of Pittsburgh School of Medicine, Pittsburgh, PA 15261; 3) University of California, San Francisco, CA 94143. |
| 409A | Mechanisms of Mot1-Mediated Transcriptional Activation. Rebekka O. Sprouse, David T. Auble. Biochemistry & Molecular Genetics, University of Virginia, Charlottesville, VA. |
| 410B | A FACT Mutation Sensitizes Cells to Transcription-Related Histone Deacetylation. Jennifer R. Stevens, Allyson F. O'Donnell, Gerald C. Johnston, Richard A. Singer. Faculty of Medicine, Dalhousie University, Halifax, Canada. |
| 411C | Biotin sensing in Saccharomyces cerevisiae is mediated by a conserved DNA element and requires the activity of biotin-protein ligase. Heike M. Pirner, Jürgen Stolz. Dept. of Cell Biology and Plant Physiology Regensburg University, Regensburg, Germany. |
| 412A | Destruction of the Ume6p transcriptional repressor by the Cdc20-directed APC/C is required for meitoic gene induction. Randy Strich, Michael Mallory, Katrina Cooper. Dept Molecular Biol, UMDNJ-SOM, Stratford, NJ. |
| 413B | FLO11 upregulation and enhanced invasive growth resulting from overexpression of Mediator and RNA polII components are dependent on the transcription factor Mss11p. Dewald Van Dyk1, 2, Richelle Sopko1,3, Helena Friesen1, Nazareth Bastajian1, 3, Brenda J. Andrews1, 2, 3, Florian F. Bauer4. 1) The Terrence Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada; 2) Banting and Best Department of Medical Research, University of Toronto, Toronto, Ontario, Canada; 3) Department of Medical Genetics and Microbiology, University of Toronto, Toronto, Ontario, Canada; 4) The Institute for Wine Biotechnology, Stellenbosch University, Stellenbosch, ZA-7600, South Africa. |
| 414C | Role of DHH1 gene in the regulation of monocarboxylic acid transporters expression in Saccharomyces cerevisiae. Neide Vieira, Sandra Paiva, Sónia Barbosa, Margarida Casal. Biology, University of Minho, Braga, Minho, Portugal. |
| 415A | Genetic analysis connects SLX5 and SLX8 to the SUMO pathway in Saccharomyces cerevisiae. Zheng Wang, Grace M. Jones, Gregory Prelich. Molecular Genetics, Albert Einstein College of Med, Bronx, NY. |
| 416B | Discrete segments of the Paf1 complex component Rtf1 mediate its multiple transcription-related functions. Marcie H. Warywoda, Kelli L. Roinick, Karen M. Arndt. Dept Biological Sciences, University of Pittsburgh, Pittsburgh, PA. |
| 417C | Interactions of Brf1 peptides with the tetratricopeptide repeat-containing subunit of TFIIIC inhibit and promote preinitiation complex assembly. Yanling Liao, Robyn Moir, Ian Willis. Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY. |
| 418A | KlSSU72: defects in restoring viability of a S. cerevisiae plasmid shuffling-ssu72 mutant strain. Maria Freire-Picos, Rosa García Díaz. Dept. Biologia Celular y Molecular, Univ.da Coruña, A Coruña, Spain. |
| 419B | Large-scale analysis of the regulation of alternative polyadenylation in Saccharomyces cerevisiae. Barbara Hoopes, Daniel Grubaugh, Shannon Larrabee, William Neidermyer. Department of Biology, Colgate University, Hamilton, NY. |
| 420C | Specificity of RNA-binding proteins in S. cerevisiae. Daniel P. Riordan1,2, Daniel Herschlag1, Patrick O. Brown1. 1) Department of Biochemistry, Stanford University, Stanford, CA; 2) Department of Genetics, Stanford University, Stanford, CA. |
| 421A | Mapping the RNA Binding Site of the Helicase Core of DEAD-box Protein Prp5. Stephanie Ruby, Heather Keys, John Stam. Molecular Genetics & Microbiology, UNM, Albuquerque, NM. |
| 422B | Inhibition of a spliceosome integrity maintenance pathway suppresses splicing defects. Brian Rymond, Sakshi Pandit. Biology Department, Univ Kentucky, Lexington, KY. |
| 423C | Characterization of Rmp1p, a unique protein component of Saccharomyces cerevesiae RNase MRP. Kelly L. Salinas, Mark E. Schmitt. Department of Biochemistry, Upstate Medical University, Syracuse, NY. |
| 424A | Factors involved in alternative RNA 3'-end processing in yeasts. Silvia Seoane, Ana M. Rodríguez-Torres, Mónica Lamas-Maceiras, María A. Freire-Picos. Dpt. Biología Celular y Molecular, Area Bioquímica University of A Coruña, A Coruña, A Coruña, Spain. |
| 425B | Impact of Nonsense-mediated mRNA decay on the global expression profile of budding yeast. Qiaoning Guan1, Wei Zheng1, Xiaosong Liu2, Shijie Tang3, Robert A. Zinkel1, Kam-Wah Tsui3, Brian S. Yandell3, 4, Michael R. Culbertson1. 1) Laboratories of Genetics and Molecular Biology; 2) Department of Physics; 3) Department of Statistics; 4) Department of Horticulture, University of Wisconsin, Madison, WI 53706. |
| 426C | Mtr4p, a putative RNA helicase, is involved in the degradation of hypomodified tRNAiMet in S. cerevisiae. xuying wang, James Anderson. Dept of biological sciences, Marquette University, milwaukee, WI. |
| 427A | Ppz phosphatases are essential for growth of yeast strains containing non-chromosomal antisuppressor determinant [ISP+]. Anna Aksenova1, Iván Muñoz2, Kirill Volkov1, Joaquin Ariño2, Ludmila Mironova1. 1) Department of Genetics, St.Petersburg State University, St.Petersburg, Russian Federation; 2) Department of Biochemistry and Molecular Biology, Universitat Autònoma de Barcelona, Barcelona, Spain. |
| 428B | Mechanism of prion species barrier at the short phylogenetic distances in yeast. Buxin Chen, Gary P. Newnam, Yury O. Chernoff. Sch. Biol., Georgia Inst. Technology, Atlanta, GA. |
| 429C | Slx5p supplements Sir2p function in promotion of growth and transcriptional silencing. Russell Darst1, Sandra García2, Melissa Krick1, Lorraine Pillus1. 1) Dept Molecular Biol, Univ California, San Diego, La Jolla, CA; 2) University of Texas Health Sciences, Center San Antonio, TX. |
| 430A | Silencing and the cell cycle in yeast. Scott G. Holmes, Kristen Martins-Taylor, Tania Rozario, Asmitha G. Lazarus. Molecular Biology, Wesleyan University, Middletown, CT. |
| 431B | PCNA, Chromatin Modifications and Silencing in S. cerevisiae. Andrew Miller, Taichi Endo, Ann L. Kirchmaier. Department of Biochemistry and Purdue Cancer Center, Purdue University, West Lafayette, IN. |
| 432C | The establishment of gene silencing at the mating type loci and telomeres. Asmitha G. Lazarus, Scott G. Holmes. Molecular Biology, Wesleyan University, Middletown, CT. |
| 433A | The cell cycle requirement for heterochromatin spreading at yeast telomeres. Kristen Martins-Taylor, Scott G. Holmes. Molecular Biology, Wesleyan Univesity, Middletown, CT. |
| 434B | Single cell dynamics of Sir-protein mediated silencing. Erin A Osborne, Jasper Rine. Molecular & Cellular Biology, UC Berkeley, Berkeley, CA. |
| 435C | New Roles for the AMP-kinase Snf1 at Adr1-regulated Glucose Repressed Genes. Chris Tachibana, Rhiannon Biddick, Ella Hsien-Wen Chang, JuanJose Infante Viñolo, G. Lynn Law, Elton T. Young. Dept of Biochemistry, University of Washington, Seattle, WA. |
| 436A | Crossing the prion species barrier in yeast. Namitha Vishveshwara, Susan W. Liebman. Univ. Of Illinois at Chicago, Chicago, IL. |
| 437B | An S. cerevisiae sir2 temperature-sensitive silencing mutant. Chia-Lin Wang, Rolf Sternglanz. Department of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, NY. |
| 438C | Bypassing the catalytic activity of Sir2p for SIR protein spreading in S. cerevisiae. Bo Yang, Ann Kirchmaier. Department of Biochemistry and Purdue Cancer Center, Purdue University, 175 S. University St., West Lafayette, IN 47907 USA. |
| 439A | Yeast N-terminal acetyltransferases are associated with polyribosomes. Bogdan Polevoda, Steven Brown, Thomas Cardillo, Sean Rigby, Fred Sherman. Dept. of Biochemistry and Biophysics, University of Rochester Medical Center, 601 Elmwood Ave., Rochester, NY 14642 USA. |
| 440B | N-terminal extension of Saccharomyces cerevisiae eRF3 translation termination factor influences suppression efficiency of sup35 mutations. Kirill V. Osipov, Kirill V. Volkov, Ludmila N. Mironova. Dept. of Genetics, St.Petersburg State University, St.Petersburg, Russian Federation. |
| 441C | SAA1, a protein related to the Saccharomyces cerevisiae gene OPI1, controls morphogenesis, secreted aspartyl protease transcription and virulence in Candida albicans. Ying-Lien Chen, Sarah Kauffman, Todd B. Reynolds. Department of Microbiology, University of Tennessee, Knoxville, TN. |
| 442A | Ergosterol Production from Cane Molasses by Genetically Modified Saccharomyces cerevisiae. Xiuping He, Xuena Guo, Pengli Cai, Yunxia Meng, Borun Zhang. The Lab of Molecular Genetics and Breeding of Yeast, Institute of Microbiology, Chinese Academy of Sciences, Beijing, P.R. China. |
| 443B | SCH9 regulates chronological longevity through mitochondrial respiratory function. Hugo Lavoie, Malcolm Whiteway. Biology, McGill University, 1205 Docteur Penfield, Montreal, Quebec, Canada, H3A 1B1. |
| 444C | Protein Architecture: Structure/Function Analysis of a Yeast Methyltransferase. Sarah Ozanick1, Janusz Bujnicki2, James Anderson1. 1) Department of Biological Sciences, Marquette University, Milwaukee, WI; 2) Laboratory of Bioinformatics and Protein Engineering, International Institute of Molecular and Cell Biology, Warsaw, Poland. |
| 445A | Determining the consequences of increased dosage of Forkhead Homolog One (FKH1): functional genetic and whole-genome expression analyses. Erin E. Patterson1, Audrey P. Gasch1, Catherine A. Fox2. 1) Laboratory of Genetics, The University of Wisconsin, Madison, WI; 2) Department of Biomolecular Chemistry, The University of Wisconsin, Madison, WI. |
| 446B | Development of tools for genetic manipulation in the osmotolerant yeast Zygosaccharomyces rouxii. Lenka Pribylova1, 2, Jacky de Montigny2, Hana Sychrova1. 1) Dept. Membrane Transport, Inst. Physiology Cz Acad Sci, Prague, Czech Republic; 2) Lab. Génétique Moléculaire, Génomique et Microbiologie, Inst. Botanique, Université Louis Pasteur, Strasbourg, France. |
| 447C | Desiccation stress response in Saccharomyces cerevisiae. Sooraj Ratnakumar1, Bharat Rash2, Michael Wilson2, Andy Hayes2, Stephen Oliver2, Alan Tunnacliffe1. 1) Institute of Biotechnology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QT, United Kingdom; 2) Faculty of Life Sciences, Michael Smith Building, University of Manchester, Oxford Road, Manchester M13 9PT, United Kingdom. |
| 448A | Effective computational modeling and analysis of transient expression of early meiosis-specific genes in budding yeast. Amir Rubinstein1, Vyacheslav Gurevich2, Ron Pinter1, Yona Kassir2. 1) Computer Science, Technion, Haifa, Israel; 2) Biology, Technion, Haifa, Israel. |
| 449B | A novel system of genetic transformation allows multiple integrations of a desired gene in Saccharomyces spp chomosomes. Odanir Guerra1, 2, Ileana Rubio3, Claudionor Silva Filho1, Regiane Bertoni1, Rute Govea1, Ana Schenberg1, Elisabete Vicente1. 1) Department of Microbiology, Biomedical Sciences Institute, University of São Paulo, São Paulo, Brazil; 2) Native Sciences Department, Campus Três Lagoas, Mato Grosso do Sul Federal University, Mato Grosso, Brazil; 3) Thyroid Study Unit, Division of Endocrinology, University of São Paulo Medical School, São Paulo, Brazil. |
| 450C | RDS2 encodes a transcriptional repressor of drug resistance genes in the human pathogen Candida albicans. Nitnipa Soontorngun1, Céline Lacroix2, André Nantel2, Bernard Turcotte1. 1) Dept. of Medicine and Biochemistry, McGill University, Montréal, Canada; 2) Biotechnology Research Institute, National Research Council, Montréal, Canada. |
| 451A | Creating wine yeasts for the production of low alcohol wines. Cristian A Varela1, Danie F Malherbe1,2, Jan H Swiegers1, Paul J Chambers1, Pierre van Rensburg2, Isak S Pretorius1. 1) The Australian Wine Research Institute, PO Box 197, Glen Osmond, Adelaide, SA 5064, Australia; 2) Institute for Wine Biotechnology, Department of Viticulture & Oenology, Stellenbosch University, Victoria Street, Stellenbosch, 7600, South Africa. |
| 452B | The genetics of volatile thiol release and modulation during wine fermentation: Tracking and manipulating the expression of key flavour-enhancing genes. Jan H Swiegers, Robyn L Willmott, Cristian A Varela, Leigh Francis, Mark Sefton, Isak S Pretorius. The Australian Wine Research Institute, PO Box 197, Glen Osmond, Adelaide, SA 5064, Australia. |
| 453C | Study of the role of a RNA Polymerase II subunit in Pseudohyphal Morphogenesis. Jiyoti Verma, Parag P. Sadhale. Dept. of Microbiology & Cell Biology, Indian Institute of Science, Bangalore-560012, India. |
| 454A | Iron regulates the cadmium toxicity partially in Saccharomyces cerevisiae.. Dong-Hyuk Heo, In-Joon Baek, Yong-Sung Park, Cheol-Won Yun. School of life sciences and biotechnology, Korea University, Seoul, KOREA. |
| 455B | Mapping the Nutrient Sensing Network in Saccharomyces cerevisiae. Shadia Zaman, Chris Farrell, Lisa Schneper, Xuiying Zhang, James R. Broach. Dept Molecular Biol, Princeton Univ, Princeton, NJ. |
| 456C | YBR261C is identified as a novel translation related gene in Saccharomyces cerevisiae using a novel large-scale approach along with focused follow-up experiments. M. Alamgir, V. Eroukova, M. Jessulat, A. Golshani. Department of Biology, Carleton University, Ottawa, ON, Canada. |
| 457A | Transcriptomics of glucose signaling at the G1/S transition. Kellie Barbara, Kristine Willis, George Santangelo. Med. Biosci. & Bioinformatics, Univ Southern Mississippi, Hattiesburg, MS. |
| 458B | Functional genomics of genes with small open reading frames (sORFs) in S.cerevisiae. James Kastenmayer1, Li Ni2, Angela Chu3, Lauren Kitchen1, Wei-Chun Au1, Hui Yang2, Carole Carter1, David Wheeler4, Ronald Davis3, Jef Boeke5, Michael Snyder2, Munira Basrai1. 1) Genetics, National Cancer Inst. NIH, Bethesda, MD; 2) Yale University; 3) Stanford University; 4) National Center for Biotechnology Information, NIH,; 5) The Johns Hopkins School of Medicine. |
| 459C | Investigation of DNA repair incompatibilities in Bakers yeast using high-density genotyping analysis. Ann Bernard1, Erin N. Smith2, Leonid Kruglyak2, Eric Alani1. 1) Molecular Biology and Genetics, Cornell University, Ithaca, NY; 2) Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ. |
| 460A | Identification of pathways regulating mitochondrial DNA copy number in Saccharomyces cerevisiae. Amy Caudy, Daniel Weitz. Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ. |
| 461B | Thermal shock replacing glass beads for cell lysis in yeast genomic DNA extraction. Guilherme T. Vancetto, Márcia M. Rosa, Sandra R. Ceccato-Antonini. Dept. Tecnologia Agroindustrial e Sócio-Economia Rural, Centro de Ciencias Agrarias, UFSCar, Araras,SP, BRAZIL. |
| 462C | Noise and Essentiality in Yeast Gene Expression. Renata C. ferreira, Francisco A. R. Bosco, Marcelo R. S. Briones. Departament of Microbiology, Fed. University of São Paulo, São Paulo, São Paulo, Brazil. |
| 463A | Exploring the yeast kinome using array-based synthetic dosage lethality and synthetic lethality screens. Dongqing Huang1, Helena Friesen1, Wei Ye1, Trinh Hoac1, Mike Cox1, 3, Richelle Sopko1, 3, Supipi Kaluarachchi1, 3, Dewald van Dyk1, 2, Brenda Andrews1, 2, 3. 1) Donnelly CCBR, Univ Toronto, Toronto, ON, Canada; 2) Banting and Best Department of Medical Research, Univ Toronto, ON, Canada; 3) Department of Medical Genetics and Microbiology, Univ Toronto, ON, Canada. |
| 464B | Analysis of Natural Variation in Yeast Sporulation Efficiency. Justin Gerke, Christina Chen, Barak Cohen. Dept Genetics, Washington Univ, St Louis, MO. |
| 465C | Rap1 and Meiosis: a model for activation and repression by a single transcription factor. Sean E. Hanlon, Jason D. Lieb. The Department of Biology, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-3280. |
| 466A | Ordered Yeast Gene Libraries for Systematic Cloning and Overexpression Analysis. Cheuk Hei Ho, Sarah Barker, Leslie Magtanong, Charles Boone. Banting and Best Department of Medical Research, University of Toronto, Toronto, Ontario, Canada. |
| 467B | Identification of Novel Protein Complexes Involved in Non-Homologous End-Joining of DNA double-stranded break. Matthew G.M. Jessulat1, J. Fillingham2, Nevan Krogan2, Jack Greenblatt2, Ashkan Golshani1. 1) Department of Biology, Carleton University, Ottawa, Ontario, Canada; 2) Best Institute, University of Toronto, Ontario, Canada. |
| 468C | Genomic Responses to Transition Metal Exposures in Yeast. YongHwan Jin1, Paul Dunlap2, Sandra McBride1, Pierre Bushel2, Hanan Al-Refai1, Jonathan Freedman1,2. 1) NSEES, Duke Univ, Durham; 2) NIEHS/NIH, RTP, NC. |
| 469A | NOVEL YEAST SPECIES: Genome remodeling during real-time speciation and adaptive evolution. Katy Kao, Gavin Sherlock. Department of Genetics, Stanford University, Stanford, CA. |
| 470B | Mapping Genetic Networks with Essential Genes in Saccharomyces cerevisiae. Zhijian Li1,2, Sondra Bahr1, Renee Brost1, Brenda Andrews1,2, Charles Boone1,2. 1) Banting and Best Department of Medical Research, University of Toronto, Toronto, ON, Canada; 2) Department of Medical Genetics and Microbiology, University of Toronto, Toronto, ON, Canada. |
| 471C | The Importance of Being SUMO-ylated. Pamela B. Meluh1,2, Yu-yi Lin1,2, Jef Boeke1,2. 1) High Throughput Biology Center (HiT), Johns Hopkins University School of Medicine, Baltimore, MD; 2) Dept. of Molecular Biology & Genetics, JHUSOM, Baltimore, MD. |
| 472A | MOLECULAR ANALYSES OF PREDICTED GENE STRUCTURES OF THE ANNOTATED Saccharomyces cerevisiae GENOME. Ugrappa Nagalkshmi, Fred Sayward, Jin Yang, Michael Snyder. MCDB, Yale University, NewHaven, CT. |
| 473B | SGD Lite: A functional genomics database containing large-scale data sets from genome-wide experiments in yeast. Rose Oughtred, Michael Livstone, Sven Heinicke, Reazur Rahman, Fan Kang, Kara Dolinski, David Botstein. Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ. |
| 474C | Combination of synthetic dosage lethality and gene expression analysis to uncover the mechanism of activity of a phospholipase A2 in S. cerevisiae. Uros Petrovic1, Mojca Mattiazzi1, Tomaz Curk2, Ashwini Jambhekar3, Heimo Wolinski4, Jan Cvetek1, Nina Trost1, Sepp D. Kohlwein4, Joseph L. DeRisi3, Blaz Zupan2,5, Igor Krizaj1. 1) Jozef Stefan Institute, Ljubljana, Slovenia; 2) University of Ljubljana, Slovenia; 3) University of California, San Francisco, CA; 4) University of Graz, Austria; 5) Baylor College of Medicine, Houston, TX. |
| 475A | Pooled analysis of epistasis in S. cerevisiae. Sarah Pierce1,3, Bob St. Onge2,3, Ron Davis1,2,3, Corey Nislow3, Guri Giaever3. 1) Dept Genetics, Stanford Univ, Palo Alto, CA; 2) Dept Biochemistry, Stanford Univ, Palo Alto, CA; 3) Stanford Genome Technology Center, Palo Alto, CA. |
| 476B | A new systematic high copy number library of the S. cerevisiae genome. Grace Marie Jones, Greg Prelich. Molecular Genetics, Albert Einstein College of Med, Bronx, NY. |
| 477C | A Facility for S. pombe and S. cerevisiae microarrays. Adam Rosebrock, Francisco Ferrezuelo, Hong Wang, Bruce Futcher, Janet Leatherwood. Microbiology, Stony Brook University, Stony Brook, NY. |
| 478A | Systematic Genetic Analysis: Quantitative Assessment of Yeast Filamentous Growth. Owen W. Ryan1, Doris Cheung1, Todd B. Reynolds2, Gerald R. Fink3, Charles Boone1. 1) Medical and Molecular Genetics, University of Toronto, Toronto, Ontario, Canada; 2) Department of Microbiology, University of Tennessee, Knoxville, TN, USA; 3) Whitehead Institute for Biomedical Research, Cambridge, MA, USA. |
| 479B | General population structure of Saccharomyces cerevisiae . Joseph Schacherer, Douglas Ruderfer, Erin Smith, Leonid Kruglyak. Lewis Sigler Institute for Integrative Genomics. Department of Ecology and Evolutionary Biology, Princeton University, Princeton, NJ 08544, USA. |
| 480C | Exploration of the function and organization of the yeast early secretory pathway through an Epistatic Mini Array Profile (E-MAP). Maya Schuldiner1, Sean R. Collins1, Natalie J. Thompson2, Vladimir Denic1, Arunashree Bhamidipati1, Thanuja Punna2, Jan Ihmels1, Brenda Andrews2, Charles Boone2, Jack F. Greenblatt2, Jonathan S. Weissman1, Nevan J. Krogan2. 1) Howard Hughes Medical Institute, Departement of Cellular and Molecular Pharmacology, University of California, San Francisco, CA 94107; 2) Banting and Best Department of Medical Research, University of Toronto, 112 College Street, Toronto, Ontario M5G 1L6, Canada. |
| 481A | Upregulation of the Saccharomyces cerevisiae DAN1 and TIR1 genes under anaerobic conditions. I. S. Ishtar Snoek1, Siew L. Tai2, Jean-Marc Daran2, Jack T. Pronk2, H. Yde Steensma1,2. 1) Dept Yeast Genetics, IMP, Leiden Univ, Leiden, Netherlands; 2) Department of Biotechnology, Delft University of Technology, Julianalaan 67, 2628 BC Delft, The Netherlands. |
| 482B | A Survey of Essential Gene Function in the Yeast Cell Division Cycle. Lisa Yu1, Lourdes Peña Castillo2, Sanie Mnaimneh2, Timothy R. Hughes2, Grant W. Brown1. 1) Department of Biochemistry, University of Toronto, Toronto ON, Canada; 2) Banting and Best Department of Medical Research, University of Toronto, Toronto ON, Canada. |
| 483C | Identification of Tyrosine Phosphorylation in Saccharomyces cerevisiae. Geeta Devgan, Daniel Gelperin, Li Kung, Kevin Wise, Michael Snyder. MCDB, Yale University, New Haven, CT. |
| 484A | Mapping kinase protein-protein interaction networks in the budding yeast S. cerevisiae using high-density protein micro-arrays. Joseph Fasolo, Michael Snyder. Mol. Cell. and Dev. Biol., Yale University, New Haven, CT. |
| 485B | Engineering S. cerevisiae to produce proteins for x-ray crystallography. Elizabeth J. Grayhack1,2, Eric M. Phizicky1,2, Erin Quartley2, Julie Babulski2, Michael G Malkowski3, George T. DeTitta3, Center for High Throughput Structural Biology. 1) Biochem/Biophy, Sch Med/Dent, Univ Rochester, Rochester, NY; 2) Center for Pediatric Biomedical Research, University of Rochester School of Medicine, Rochester, New York 14642, USA; 3) Hauptman-Woodward Medical Research Institute, 700 Ellicott St., Buffalo, New York. |
| 486C | Toward the phosphoproteome of Cdc28. Kolbrun S. Kristjansdottir, Don Wolfgeher, Stephen J. Kron. Center for Molecular Oncology, The University of Chicago, Chicago, IL. |
| 487A | Using lectin screens of proteome chips to study glycosylation in S. cerevisiae. Li A Kung1, Sheng-Ce Tao2, Paul Hitchen3, Anne Dell3, Heng Zhu2, Michael Snyder1. 1) MCDBiology Department, Yale University, New Haven, CT; 2) Pharmacology Department, Johns Hopkins University, Baltimore, MD; 3) Division of Molecular Biosciences, Imperial College, London, United Kingdom. |
| 488B | Using Peptide Libraries to Determine Phosphorylation Specificity of Yeast Kinases. Janine Mok1, Philip Kim2, Mark Gerstein2, Michael Snyder3, Benjamin Turk4. 1) Dept Genetics & Development, Yale Univ, New Haven, CT; 2) Dept Molecular Biophysics & Biochemistry, Yale Univ, New Haven, CT; 3) Dept Molecular, Cellular, & Developmental Biology, Yale Univ, New Haven, CT; 4) Dept Pharmacology, Yale Univ, New Haven, CT. |
| 489C | Determining divergence of S.cerevisiae paralogs through protein interactions. Gabriel A Musso, Andrew Emili, Zhaolei Zhang. Medical Genetics, University of Toronto, Toronto, Ontario, Canada. |
| 490A | Redesign of the Protein Information Page at SGD. Rob Nash1, Rama Balakrishnan1, Ben Hitz1, Karen R. Christie1, Maria C. Costanzo1, Kara Dolinski2, Selina S. Dwight1, Stacia R. Engel1, Dianna G. Fisk1, Jodi E. Hirschman1, Eurie L. Hong1, Mike S. Livstone2, Rose Oughtred2, Julie Park1, Marek S. Skrzypek1, Chandra L. Theesfeld1, Gail Binkley1, Qing Dong1, David Botstein2, J. Michael Cherry1. 1) Department of Genetics, Stanford University, 300 Pasteur Dr., Stanford, CA. 94305, U.S.A; 2) Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ 08544, U.S.A. |
| 491B | Using a multiplex approach to monitor the signaling cascades triggered by adiponectin via iTRAQ Reagents in conjunction with mass spectrometry. Lisa M. Regalla1, Stan M. Stevens Jr.2, Thomas J. Lyons1. 1) Department of Chemistry, University of Florida, Gainesville, FL; 2) Proteomics Core, University of Florida, Gainesville, FL. |
| 492C | Examining Protein Interactions Using the Large-Scale Pull-down Approach and Endogenously Tagged Yeast Strains: The ‘Cross and Capture’ System. Bernhard Suter1, Michael Fetchko2, Ralph Imhof1, Ingrid Stoffel-Studer2, Caroline Zbinden2, Lucia Beneti2, Jacqueline Hort2, Igor Stagljar1. 1) Donelly Center for Cellular and Biomolecular Research (dCCBR), University of Toronto, Canada; 2) Institute of V. Biochemistry and Molecular Biology, University of Zurich, Switzerland. |
| 493A | Analysis of Localization of Yeast Nucleolar Proteins under Environmental Stresses. Min-Kyung Sung, Won-Ki Huh. Department of Biological Sciences, and Research Center for Functional Cellulomics, Seoul National University, Seoul 151-747, Korea. |
| 494B | Genome-wide analysis of yeast SH3 domains. Raffi Tonikian1,2, Gary Bader1, Jennifer Marles1, Alan Davidson1, Charles Boone1,2, Sachdev Sidhu3. 1) Department of Molecular and Medical Genetics, University of Toronto, Toronto, Ontario, Canada; 2) Banting and Best Department of Medical Research, University of Toronto, Toronto, Ontario, Canada; 3) Department of Protein Engineering, Genentech, Inc., South San Francisco, CA, USA. |
| 495C | Identification of Taxol Drug Targets in Yeast. Kevin J. Wise, Dane Mejias, Daniel M. Gelperin, Li A. Kung, Michael Snyder. Yale University, New Haven, CT. |
| 496A | Development of a Flow Cytometry-based High Throughput Screening Method for Protein-Protein Interaction Study. Weon Bae, Jianhong Zhou, Hong Cai. Bioscience Division, Los Alamos National Laboratory, Los Alamos, NM. |
| 497B | Meiotic segregation of isoamyl alcohol induced filamentation and fermentation trait in an industrial strain of Saccharomyces cerevisiae used for ethanol production. //. Sandra R. Ceccato-Antonini, Heloisa G. Brunetto, Viviane S. Miranda, Emanuele Paiva, Guilherme T. Vancetto. Dept.Tecnologia Agroindustrial e Socio-Economia Rural, Centro de Ciencias Agrárias, UFSCar, Araras, SP, BRAZIL. |
| 498C | Novel yeast two-hybrid selection protocols developed in liquid medium: one option for robots and another for simple single culture. Erica M. Queiroz, Elisa Donnard, J. Miguel Ortega. Bioquimica e Imunologia, ICB, UFMG, Belo Horizonte, MG, Brazil. |
| 499A | Mapping Novel Traits by Array-assisted Bulk Segregant Analysis in Saccharomyces cerevisiae. Maitreya Dunham1, Matthew Brauer1,2, Cheryl Christianson1, Dave Pai1. 1) Lewis-Sigler Inst, Princeton Univ, Princeton, NJ; 2) Department of Molecular Biology, Princeton Univ, Princeton, NJ. |
| 500B | Genetic analysis of yeast for winemaking. Michael Harsch, Heather Niederer, Soon Lee, Keith Richards, Matt Goddard, Richard Gardner. Sch Biological Sci, Univ Auckland, Auckland, New Zealand. |
| 501C | Development of a Glucose-Inducible Degron to Study Essential Genes in Saccharomyces cerevisiae and Candida albicans. Yanfang Jiang, Mark Johnston. Center for Genome Sciences, Department of Genetics, Washington University, St Louis, MO 63108. |
| 502A | Small Molecule-Directed Protein Mislocalization: Technology and Applications. Prasanthi Geda, Nike Bharucha, Craig Dobry, Jason Gestwicki, Anuj Kumar. LSI/MCD Biol, University of Michigan, Ann Arbor, MI. 48109-2216. |
| 503B | Systematic profiling of cellular phenotypes and gene function using cell microarrays. Ram Narayanaswamy, Wei Niu, Alex Scouras, Traver Hart, Matthew Davis, Jonathan Davies, Andrew Ellington, Vishwanath Iyer, Edward Marcotte. Inst for Cell and Mol Biology, University of Texas, Austin, TX. |
| 504C | Development of imaging-based genetic assays using yeast spheroplast microarrays. Wei Niu, Ram Narayanaswamy, Andrew D. Ellington, Vishwanath R. Iyer, Edward M. Marcotte. Institute for Cellular and Molecular Biology University of Texas, Austin, TX 78712. |
| 505A | Development of "calling cards" for DNA binding proteins. Haoyi Wang, Robi Mitra, Mark Johnston. Genetics, Washington University, Saint Louis, MO. |
| 506B | Now you too can analyze data from yeast TAG microarrays. Daniel Yuan1,2, Jef Boeke1, Rafael Irizarry2. 1) Dept Molecular Biol & Genetics, Johns Hopkins Univ Sch Med, Baltimore, MD; 2) Dept Biostatistics, Johns Hopkins Bloomberg Sch Public Health, Baltimore, MD. |
| 507C | A Synthetic Network to benchmark reverse-engineering algorithms: can we map transcriptional gene networks in Eukaryotes? IRENE CANTONE1,2, MARIA P COSMA1,2, DIEGO di BERNARDO1,2. 1) Telethon Institute of Genetics and Medicine (TIGEM), Naples, Italy; 2) European School of Molecular Medicine (SEMM), Naples. |
| 508A | BioGraphNet: a framework for just-in-time integration of static and dynamic biological networks. Francis D Gibbons, Gabriel Berriz, Frederick P Roth. Dept. of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA. |
| 509B | Protein complexes and functional pathways in chromosome function. Jack F. Greenblatt1, Nevan J. Krogan1, Sean Collins2, Vincent Cheung3, Maya Schuldiner2, Huiming Ding1, Michael Keogh4, Stephen Buratowski4, Brenda Andrews1, Charlie Boone1, Andrew Emili1, Brendan Frey3, Jonathan Weissman2. 1) Banting & Best Med.Research, University of Toronto, Toronto, Ontario, Canada; 2) Howard Hughes Medical Institute, University of California, San Francisco, CA; 3) Dept. of Electrical and Computer Engineering, University of Toronto, Toronto, Ontario, Canada; 4) Dept. of Biochemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA. |
| 510C | Combined experimental and model-based analysis of transcriptional and metabolic responses in Saccharomyces cerevisiae. Qiang Hua, Byung-Kwan Cho, Vasiliy Portnoy, Markus Herrgard, Bernhard Palsson. Department of Bioengineering University of California, San Diego La Jolla, CA 92093-0412. |
| 511A | Untangling protein-protein interaction networks in yeast. Vladimir Jojic1, Quaid Morris2. 1) Computer Science, University of Toronto, Ontario, Canada; 2) Banting and Best Department of Medical Research, University of Toronto, Ontario, Canada. |
| 512B | Modeling the adaptive response to oxidative stress. Ryan Kelley1, Trey Ideker1,2. 1) Bioinformatics, UC San Diego, La Jolla, CA; 2) Bioengineering, UC San Diego, La Jolla, CA. |
| 513C | A Systematic Screen for Over-expression Suppressors of Lethal Mutations. Bryan A Kraynack1, Yoshiko Kon2, Michael Baitaluk3, KiriLynn Svay1, David Galas1,4, Elizabeth Grayhack2, Amarnath Gupta3, Alpan Raval1,5, Animesh Ray1, Eric Phizicky2. 1) Keck Graduate Institute, Claremont, CA; 2) University of Rochester Medical School, Rochester, NY; 3) University of California, San Diego, CA; 4) Institute for Systems Biology, Seattle, WA; 5) School of Mathematical Sciences, Claremont Graduate University, Claremont, CA. |
| 514A | Transcriptional co-regulation of genome-wide protein complexes in S. cerevisiae. Ho F. Lee, Tomasz Zemojtel, Thomas Manke, Martin Vingron. Computational Molecular Biology, Max Planck Institute for Molecular Genetics, Berlin, Germany. |
| 515B | Identification of new genes involved in ribosome biogenesis from Saccharomyces cerevisiae functional gene network. Zhihua Li, Insuk lee, Edward Marcotte. The University of Texas at Austin, Austin, TX. |
| 516C | Systematic mapping of DNA damage and repair pathways using small molecule inhibition with combinatorial gene deletions. Julia S. Oh1, Robert St. Onge1, Rami Ramamurthy2, Michael Proctor1, Eula Fung1, Ronald Davis1, Corey Nislow1, Frederick Roth2, Guri Giaever1. 1) Department of Genetics, Department of Biochemistry, Stanford University, Stanford, California 94305; 2) Department of Biological Chemistry and Molecular Pharmacology, Harvard University, Boston, MA 02115. |
| 517A | Moreau: a cross-species genotype/phenotype database for comparative genetics. Yan Qi1, Reiri Sono1, Joel Bader1,2. 1) Biomedical Engineering, Johns Hopkins University, Baltimore, MD; 2) High Throughput Biology, Institute for Basic Biomedical Sciences, Johns Hopkins School of Medicine. |
| 518B | A genetic network for DNA-transfection - yeast as a model. Sean-Patrick Riechers, Ulf Stahl, Christine Lang. Department Microbiology and Genetics, Technische Universität Berlin, Berlin, Germany. |
| 519C | A Predictive Model of the Oxygen Sensing and Regulatory Network in Yeast. Li Zhang1, Anshul Kundaje2, Changgui Lan1, Mei Zhou1, Christina Leslie3. 1) Environmental Hlth Sci/SPH, Columbia Univ, New York, NY; 2) Department of Computer Science Columbia University, New York, NY; 3) Center for Computational Learning Systems Center for Computational Biology and Bioinformatics Columbia University New York, NY. |
| 520A | New genetic and physical interaction data in the Saccharomyces Genome Database. Maria C. Costanzo1, Rose Oughtred2, Kara Dolinski2, Teresa Reguly3, Ashton Breitkreutz3, Lorrie Boucher3, Nizar Batada3, Bobby-Joe Breitkreutz3, Eurie L. Hong1, Mike Tyers3, J. Michael Cherry1, the Saccharomyces Genome Database project. 1) Department of Genetics, Stanford University, Stanford, CA; 2) Department of Molecular Biology, Princeton University, Princeton, NJ; 3) Samuel Lunenfeld Research Institute and University of Toronto, Toronto, ON, Canada. |
| 521B | In silico prediction of mutations that bypass cell cycle checkpoint arrest. Jesse P. Frumkin, Bryan A. Kraynack, Herbert M. Sauro, Animesh Ray. Keck Graduate Institute, Claremont, CA 91711. |
| 522C | Connectivity in the Yeast Cell Cycle Transcription Network: Inferences from Neural Networks. Christopher E. Hart1, Eric Mjolsness2, Barbara J. Wold1. 1) Division of Biology, Caltech, Pasadena, CA; 2) University of California, Irvine, Institute for Genomics and Bioinformatics, School of Information & Computer Science, Irvine, CA 92697. |
| 523A | Connecting extracellular metabolomic profiles to intracellular metabolic states in yeast. Monica Mo, Markus Herrgard, Gregory Hannum, Bernhard Palsson. Department of Bioengineering University of California, San Diego La Jolla, CA 92093-0412. |
| 524B | Fishing for function in the sea of gene expression. Matthew A. Hibbs1,2, Kai Li1, Olga G. Troyanskaya1,2. 1) Department of Computer Science, Princeton, NJ; 2) Lewis-Sigler Institute for Integrated Genomics, Princeton, NJ. |
| 525C | Distinguishing core annotations from those derived from large-scale experiments or computational predictions. Benjamin C Hitz, Rama Balakrishnan, Karen Christie, Eurie Hong, J. Michael Cherry, The Saccharomyces Genome Database project. Genetics, Stanford University, Stanford, CA. |
| 526A | Where have all the interactions gone? Estimating the coverage of two-hybrid protein interaction maps. Hailiang Huang1, 4, Bruno M. Jedynak2, 3, Joel S. Bader1, 4. 1) Department of Biomedical Engingeering, Johns Hopkins University, Baltimore, MD 21218; 2) Department of Applied Mathematics and Statistics, Johns Hopkins University; 3) Laboratoire de Mathématiques Paul Painlevé, USTL; 4) High-Throughput Biology Center, Johns Hopkins School of Medicine, Baltimore, MD 21205. |
| 527B | Yeast Genome Resources at NCBI. Patti M. Sherman, Deanna Church, Donna Maglott, Kim Pruitt, Greg Schuler, Tatiana Tatusova. National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD. |
| 528C | SIMBA: Organization of the Yeast Molecular Network by Integrated Analysis of Genome-wide Data. Israel Steinfeld1,2, Amos Tanay1, Martin Kupiec2, Ron Shamir1. 1) School of Computer Science, Tel-Aviv University, Tel Aviv, Israel; 2) Department of Molecular Biology and Biotechnology, Tel-Aviv University, Tel Aviv, Israel. |
| 529A | Analysis of transcription regulatory associations in Saccharomyces cerevisiae using the YEASTRACT database. M. C. Teixeira1, P. Monteiro2, S. Tenreiro1, N. Mira1, A. M. Carvalho2, N. Mendes2, A. Casimiro2, C. Nogueira2, C. Oliveira2, A. T. Freitas2, A. L. Oliveira2, I. Sá-Correia1. 1) BSRG, CEBQ, Inst Superior Tecnico, Lisbon, Portugal; 2) KDBIO/ALGOS, INESC-ID, Lisbon, Portugal. |
| 530B | A local clustering algorithm for discovering functional modules from the synthetic lethal interaction network in yeast. Ping Ye1, 2, Joel Bader1, 2. 1) Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD; 2) High Throughput Biology Center, Johns Hopkins University School of Medicine, Baltimore, MD. |
| 531C | Investigating the functional redundancy provided by duplicate genes. Jed Dean1, Jerel C. Davis2, Dmitri A. Petrov2, Ronald W. Davis1. 1) Stanford Genome Technology Center, Palo Alto, CA; 2) Department of Biological Sciences, Stanford University, Stanford, CA. |
| 532A | Array-CGH using 2-species microarrays reveals differences and similarities in genome rearrangements among strains of the hybrid lager yeast S. pastorianus that correlate with sequence and phenotype differences. Barbara Dunn, Fiona Wainwright, Gavin Sherlock. Dept Genetics, Stanford Univ Medical Sch, Stanford, CA. |
| 533B | Assessment of nucleotide variation in experimentally evolved yeast. David Gresham, David Botstein, Leonid Kruglyak, Maitreya Dunham. Lewis Sigler Institute, Princeton University, Princeton, NJ. |
| 534C | Evolutionary fate of duplicated genes in yeast. Yuanfang Guan1, 2, Maitreya Dunham2, Olga Troyanskaya2,3. 1) Molecular Biology, Princeton University, Princeton, NJ; 2) Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ; 3) Department of Computer Science, Princeton University, Princeton, NJ. |
| 535A | The evolution of the genetic switch of the galactose utilization (GAL) pathway. Chris Todd Hittinger, Sean B. Carroll. Howard Hughes Medical Institute, Laboratory of Genetics, University of Wisconsin-Madison, Madison, WI. |
| 536B | Multilocus sequence analysis reveals biogeography, migration, and absence of admixture among wild Saccharomyces populations. H Kuehne1, H Murphy2, C Francis2, P Sniegowski2. 1) Biological Sciences, Univ Montana, Missoula, MT; 2) Dept Biology, Univ Pennsylvania, Philadelphia, PA. |
| 537C | Sympatric natural populations of Saccharomyces cerevisiae and Saccharomyces paradoxus display different genetic structures. H Kuehne1, H Murphy2, C Francis2, P Sniegowski2. 1) Biological Sciences, Univ Montana, Missoula, MT; 2) Dept Biology, Univ Pennsylvania, Philadelphia, PA. |
| 538A | Variation in stress sensitivity and whole-genome expression in natural strains of Saccharomyces. Daniel J Kvitek, Omar Salgado, John Painter, Audrey P Gasch. Laboratory of Genetics, UW - Madison, Madison, WI. |
| 539B | Putative species-specific ORFs in the Saccharomyces cerevisiae genome. Qian-Ru Li1,2, Jing-Dong Jackie Han1,2,3, Stanley Tam1,2, Michael E. Cusick1,2, David Hill1,2, Marc Vidal1,2. 1) Center for Cancer Systems Biology, Dana-Farber Cancer Institute,Boston, MA; 2) Dept. of Genetics,Harvard Medical School,Boston,MA; 3) Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China. |
| 540C | A database of protein orthology, cross-species complementation data, and disease information. Michael S. Livstone1, Rose Oughtred1, Sven Heinicke1, Charles Lu2, Fan Kang1, Kara Dolinski1, David Botstein1,2. 1) Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ; 2) Department of Molecular Biology, Princeton University, Princeton, NJ. |
| 541A | Acquiring of new function and duplication in MAP Kinases. Areez M Mody1, Joan Weiner1, Sharad Ramanathan1,2. 1) Bauer Center of Genomics, Harvard University, Cambridge, MA; 2) Bell Labs, Murray Hill NJ 07974. |
| 542B | Multiple chromosome rearrangements in evolving glucose-limited yeast populations. Charlotte Paquin1, Maitreya Dunham2, Julian Adams3, David Botstein2. 1) Dept Biological Sci, Univ Cincinnati, Cincinnati, OH; 2) Lewis-Sigler Inst Integrative Genetics, Princeton Univ, Princeton, NJ; 3) Dept Cell/Mol/Dev Biology, Univ Michigan, Ann Arbor, MI. |
| 543C | Population genomic analysis of outcrossing and recombination in yeast. Douglas M. Ruderfer1, 2, Stephen C. Pratt1, 2, Hannah Seidel1, 2, Leonid Kruglyak1, 2. 1) Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ; 2) Department of Ecology & Evolutionary Biology, Princeton University, Princeton, NJ. |
| 544A | Analysis of adaptive evolution in yeast. Joshua Witten, Christina Chen, Barak Cohen. Dept Genetics, Washington Univ Sch Medicine, St Louis, MO. |
| 545B | Genome-wide transcription factor binding in a diverse set of S. cerevisiae strains. Christopher M. Yellman, Y.K. Hugo Lam, Michael Snyder. MCDB, Yale University, New Haven, CT. |
| 546C | Genome-wide functional analysis of the Helicobacter pylori virulence factor CagA in yeast indicates an inhibitory role in endocytosis. Junko K. Akada1, Takao Kitagawa3, Tomoko Matsuo3, Hisashi Hoshida3, Kazuyuki Nakamura1, Hiroki Aoki2, Rinji Akada3. 1) Department of Biochemistry and Biomolecular Recognition; 2) Department of Molecular Cardiovascular Biology, Yamaguchi University School of Medicine; 3) Department of Applied Chemistry and Chemical Engineering, Faculty of Engineering, Yamaguchi University, Japan. |
| 547A | Using plasmoduction-based synthetic dosage lethality screens in Saccharomyces cerevisiae to identify novel drug targets for cancer therapy. Samantha Ciccone, Robert Reid, Rodney Rothstein. Genetics & Development, Columbia Univ. Medical Center, New York, NY. |
| 548B | Genetics, Ecology and Evolution of Resistance to Hydrogen Peroxide in Saccharomyces cerevisiae. Stephanie Diezmann, Fred Dietrich. Mol. Genetics and Microbiology, Duke University Medical Center, Durham, NC. |
| 549C | Indole-3-acetic acid: A quorum sensing molecule in S. cerevisiae? Ally Hunter, Reeta Prusty. Biology, WPI, Worcester, MA. |
| 550A | Identification of a small molecule that selectively kills methylthioadenosine phosphorylase deficient S. cerevisiae. Yuwaraj Kadariya, Baiqing Tang, Warren D. Kruger. Human Genetics, Fox Chase Cancer Center, Philadelphia, PA. |
| 551B | A Metabolomic Approach to Understand the Thiol Toxicity Using Saccharomyces Cerevisiae As a Model System. Arun Kumar, Lijo John, Shantanu Sengupta. From Institute of Genomics and Integrative Biology, Mall Road, Delhi-110007, India. |
| 552C | HIV-1 Reverse Transcription: Uncovering Genetic Diversity and Drug Resistance in Yeast. Dwight V. Nissley1, 2, David J. Garfinkel2, Jeffrey N. Strathern2. 1) BRP, SAIC-Frederick, Inc., Frederick, MD; 2) GRCBL, NCI-Frederick, Frederick, MD. |
| 553A | A requirement for precise regulation of intracellular arginine levels in juvenile Batten disease. Seasson N Phillips, Devin Wolfe, David A, Pearce. Biochemistry, University of Rochester , Rochester, NY. |
| 554B | Capability of Saccharoyices cerevisiae glucantansferase Bgl2p for fiber formation may serve as a risk factor in systemic amyloidosis induction. Tatiana Plotnikova, Katerina Akcipetrova, Tatyana Kalebina. Molecular Biology, Moscow State University, Moscow, Russian Federation. |
| 555C | Candida albicans b-1,3-glucan synthase gene GSL2contributes to echinocandin, azole, high salt, and thermal stress tolerance. Shriya Raj, Santosh Katiyar, Thomas Edlind. Microbiology and Immunology, Drexel University College of Medicine, Philadelphia, PA. |
| 556A | Plasmoduction-based synthetic dosage lethality screens with DNA topoisomerase I alleles identify novel pathways affecting camptothecin sensitivity in Saccharomyces cerevisiae. Robert Reid, Ivana Sunjevaric, David Alvaro, Rodney Rothstein. Dept. Genetics & Development, Columbia University Medical Center, New York, NY. |
| 557B | Yeast killer toxins as novel broad-spectrum antimycotics? Manfred Schmitt, Frank Breinig. FR 8.3 Mikrobiologie Geb A l.5, Angewandte Molekularbiologie, Saarbrucken, Germany. |
| 558C | Isolating small molecule inhibitors of Pseudomonas aeruginosa essential and virulence genes using a yeast phenotypic screen. Anthony Arnoldo1, Lana Ljuma1, Leonardo Brizuela2, Stephen Lory3, Antonio Bedalov4, Igor Stagljar1. 1) Donnelly Centre for Cellular & Biomolecular Research (dCCBR), University of Toronto, ON, Canada; 2) Harvard Institute of Proteomics, Harvard Medical School, Boston MA, USA; 3) Institute of Microbiology and Molecular Biology. Harvard Medical School, Boston MA, USA; 4) 4Clinical Research and Human Biology Divisions, Fred Hutchinson Cancer Research Center, Seattle WA, USA. |
| 559A | Synergistic Effects of Small Molecule Inhibitors of the Budded-to-Hyphal-Form Transition in the Pathogenic Yeast Candida albicans. Benjamin C. Stark1, Kurt Toenjes2, Joy-El Barbour1, Douglas I. Johnson1. 1) Department of Microbiology and Molecular Genetics, University of Vermont, Burlington, VT; 2) Department of Biological and Physical Sciences, Montana State University-Billings, Billings, MT. |
| 560B | Gene expression profiling of Sake yeast in ethanol stress. Yoshio Araki2, Maiko Nishida1, Hong Wu2, Takeshi Akao1, Hitoshi Shimoi1. 1) Nat. Res. Inst. of Brewing, Higasi-Hirosima, Japan; 2) BRAIN. |
| 561C | Gene expression response impacting desiccation stress tolerance for Cryptococcus nodaensis (nomen nudem) OH 182.9 using cross-species microarray analysis. Zonglin L. Liu, Dave A. Schisler, Shouan Zhang. National Center for Agricultural Utilization Research, USDA-ARS, Peoria, IL. |
| 562A | Pdr1 regulated multidrug resistance in Candida glabrata: gene disruption and genome-wide expression studies. John-Paul Vermitsky1, Kelly Earhart2, W. Lamar Smith1, Ramin Homayouni2, P. David Rogers2, Thomas Edlind1. 1) Drexel University College of Medicine, Philadelphia, PA., 19129; 2) University of Tennessee Health Science Center, Memphis, TN, 38163. |
| 563B | A Systematic Approach to Understanding Acquired Stress Resistance in Yeast. David B. Berry, Audrey P. Gasch. Laboratory of Genetics, UW: Madison, Madison, WI. |
| 564C | Metabolic Profiling Reveals a Conserved Response to Starvation in Yeast and Bacteria. Matthew Brauer1,2, Jie Yuan1,3, Wenyun Lu2,3, Elizabeth Kimball2,3, David Botstein1,3, Joshua Rabinowitz2,3. 1) Lewis-Sigler Inst. for Integrative Genomics, Princeton University, Princeton, NJ., 08544; 2) Dept. of Molecular Biology; 3) Dept. of Chemistry. |
| 565A | Improving data presentation on Locus Summary pages at the Saccharomyces Genome Database. Eurie L. Hong1, Julie Park1, Stacia R. Engel1, Dianna G. Fisk1, Kara Dolinski2, David Botstein2, J. Michael Cherry1, the Saccharomyces Genome Database project. 1) Department of Genetics, Stanford University, 300 Pasteur Drive, Stanford, CA, 94305-5120, USA; 2) Department of Molecular Biology, Princeton University, Princeton, NJ 08544, USA. |
| 566B | Yeast Genetic Resource Center Japan supported by National BioResource Project. Yoshinobu Kaneko1, Aki Tada1, Shikiko Murakami2, Taro Nakamura2, Satoshi Harashima1, Chikashi Shimoda2. 1) Dept Biotechnology, Grad School Engr, Osaka Univ, Suita, Osaka, Japan; 2) Dept Biology, Grad School Science, Osaka City Univ, Sumiyoshi-ku, Osaka, Japan. |
| 567C | Studying natural life span variation in yeast. Hong Qin1, Meng Lu1, Joel Byam2, David Goldfarb2. 1) Ctr for Aging & Dev Biol, Univ Rochester, Rochester, NY; 2) Department of Biology, University of Rochester, NY. |
| 568A | Regulation of Yeast Osmotin Receptor Homologs by Alterations in Lipid Metabolism. Nancy Villa1, Charlene Alford2, Ashley Cowart2, Yusuf Hannun2, and Tom Lyons1. 1) Department of Chemistry, University of Florida, Gainesville, FL; 2) Medical University of South Carolina, Charleston, SC. |
| 569B | An Investigation of the Widely Used Yeast Genomic ORF Deletion Strain Collection. J Zhou1, Pushpa Gujjari1, Cathy Catranis1, Marian McKee1, Jef Boeke2. 1) American Type Culture Collection,10801 University Blvd, Manassas, VA 20110; 2) Johns Hopkins University School of Medicine, 339 Broadway Research Building, 733 North Broadway, Baltimore, MD 21205. |
| 570C | An in silico freshman laboratory as an introduction to bioinformatics. Jill B. Keeney, Randy Bennett. Biology, Juniata College, Huntingdon, PA. |
| 571A | Teaching Systems Biology: An Active Learning Approach. Anuj Kumar. LSI/MCD Biol, Univ Michigan/LSI, Ann Arbor, MI. 48109-2216. |