XXIth International Conference on Yeast Genetics and Molecular Biology: Invited Lectures
| Opening Lectures |
Fungi and the immune system: when worlds collide.
Gerald Fink
Biology, Whitehead/MIT, Nine Cambridge Ctr, Cambridge, MA 02467, USA
In memory of Ira Herskowitz
Yeast copper transporters: delivery of essential nutrients and anti-cancer drugs
Dennis J. Thiele
Biological Chemistry, Univ. Michigan Medical School, 1301 Catherine Road, Ann Arbor, MI 48109-0606. USA
| Plenary Session 1 - Chromosomes and Nucleus |
Splitting sister chromatids.
Kim Nasmyth
Nasmyth lab., IMP, Dr. Bohr-Gasse 7, Vienna, A-1030, Austria
The yeast kinetochore protein complex and its role in genome stability.
Philip Hieter (1), Vivien Measday (1), Isabelle Pot (1), Kristin Baetz et al. (1), Stanley Fields et al. (2), Charles Boone et al. (3), Katsumi Kitagawa et al. (4)
(1) Biotechnology Laboratory, University of British Columbia, 980 West 28th Avenue, Vancouver, V5Z 4H4, Canada ; (2) University of Washington, Seattle, USA; (3) University of Toronto, Ontario, Canada; (4) St Jude Children's Research Hospital, Memphis, USA
Looking at recombination in living cells.
Rodney Rothstein (1), Uffe Mortensen (2), Michael Lisby (1)
(1) Genetics & Development, Columbia Univ., Coll. of P & S, 701 West 168th St., New York, NY 10032-2704, USA ; (2) Center for Process Biotechnology, BioCentrum-DTU, Technical University of Denmark, Bldg. 223, DK-2800 Lyngby, Denmark
Structural analysis of the spindle pole body in living cells by fluorescence resonance energy transfer.
Eric Muller, Dale Hailey, Brian Snydsman, Tennessee Yoder, Mark McElwain, Trisha Davis
Department of Biochemistry, University of Washington, Box 357350, Seattle, WA 98195, USA
| Plenary Session 2 - Genomes and Functional Analysis |
Large-scale Mapping of Genetic Networks with Ordered Arrays of Yeast Deletion Mutants.
Charles Boone
Banting and Best Department of Medical Research, University of Toronto, Toronto, ON, Canada, M5G 1L6
Global analysis of biochemical activities using protein chips.
Michael Snyder, Heng Zhu, Metin Bilgin, Jason Ptacek, David Hall, Geeta Devgan, Mark Gerstein, et al.
MCDB, Yale University, PO Box 208103, New Haven, CT 06520, USA
Saccharomyces cerevisiae and Ashbya gossypii : Conserved gene sets but different life styles.
Fred Dietrich (1), Sophie Brachat (1), Sylvia Voegeli (1), Anita Lerch (1), Krista Gates (2), Tom Gaffney (2), Peter Philippsen (1)
(1) Applied Microbiology, Biozentrum University of Basel, Klingelbergstr. 50, Basel, 4056, Switzerland ; (2) Syngenta, Research Triangle Park, NC, USA
Exploiting Evolution's Experiments to Find Functional Sequences in the Yeast Genome.
Paul Cliften, Priya Sudarsanam, Ashwin Desikan, Lucinda Fulton, Bob Fulton, Robert Waterston, Barak Cohen, Mark Johnston
Genetics, Washington University, 660 S. Euclid Ave., St. Louis, MO 63110, USA
Comparative genomics of Hemiascomycetous yeasts: the systematic sequencing of Candida glabrata, Kluyveromyces lactis, Debaryomyces hansenii, Yarrowia lipolytica.
From yeast to moss: glucose sensing and signaling in a new model organism.
Mattias Thelander, Tina Olsson, Hans Ronne
Department of Plant Biology, Swedish Univ of Agric Sciences, Box 7080, Uppsala, SE-75007, Sweden
| Plenary Session 3 - Yeast and Human |
Regulation of aging by SIR2.
Leonard Guarente, Lin Su-ju
Biology, MIT, 77 Mass. Ave., Cambridge, 02139, USA
Yeast prions: biology and mechanisms.
Reed Wickner (1), Herman Edskes (1), Ulrich Baxa (1), Alasdair Steven (2), Tibor Roberts (1), Eric Ross (1), Michael Pierce (1), Andreas Brachmann (1)
(1) Lab of Biochemistry & Genetics, NIDDK, NIH, 8 Center Dr. MSC0830, Bethesda, MD 20892-0830, USA ; (2) Lab of Structural Biology, NIAMS, NIH, Bethesda, MD, USA
Saccharomyces cerevisiae as a model of human fungal pathogens.
Joseph Heitman
Mol. Genetics & Microbioly, Duke University, Research Dr, Bx 3546, Durham, NC 27710, USA
Chemical Genomics in Yeast via HaploInsufficiency Profiling (HIP).
Guri Giaever (1), Patrick Flaherty (2), Adam P. Arkin (2), Daniel F. Jaramillo (1), Michael Proctor (1), Angela M. Chu (1), Ronald W. Davis (1)
(1) Stanford Genome Technology Center, Department of Biochemistry, 855 California Ave., Palo Alto, CA 94304, USA ; (2) Departments of Bioengineering and Chemistry, University of California, Berkeley and Physical Biosciences Division, Lawrence Berkeley National Laboratory, Howard Hughes Medical Institute, Berkeley, California 94720-1770, USA
| Plenary Session 4 - Control of Growth and Proliferation |
Regulation of chromosome segregation in mitosis and meiosis.
Frank Stegmeier, Rosella Visintin, Damien D'Amours, Adele Marston, Brian Lee, Angelika Amon
Center for Cancer Research, MIT, 77 Mass Ave, E17-233, Cambridge, MA 02139, USA
Mechanisms ensuring genome integrity in budding yeast.
Maria Pia Longhese, Valeria Viscardi, Enrico Baroni, Giovanna Lucchini
Dip. Biotecnologie e Bioscienze, Università di Milano-Bicocca, P.zza della Scienza, Milan, 20126, Italy
TOR signalling and control of cell growth.
Michael N. Hall
Biozentrum, University of Basel, Klingelbergstr 70, Basel, 4056, Switzerland
Ribosome Synthesis and the Cell-Cycle: Integration or Opportunism?
Marlene Oeffinger (1), Alessandro Fatica (2), Elisabeth Petfalski (1), David Tollervey (1)
(1) Wellcome Trust Centre for Cell Biolology, Edinburgh, Scotland ; (2) Dip. Genetica e Biologia Molecolare, Universita' di Roma, Italy
| Plenary Session 5 - Shaping the Yeast Cell |
Axis selection during yeast cell polarization.
John R. Pringle (1), Laura Schenkman (1), Amos Mckenzie (1), Kenichi Nakashima (1), Nicolas Page (2)
(1) Department of Biology, University of North Carolina, 421 Fordham Hall, Chapel Hill, NC 27599, USA ; (2) Institute of Biochemistry, Eidgenoessische Technische Hochschule, Zurich, Switzerland
How fission yeast divide in the middle.
Fred Chang, Robert Pelham, Tetsuya Takeda
Microbiology, Columbia University, 701 168th St., New York, NY 10032, USA
Membrane targeting and initiation of prospore membrane formation at the spindle pole bodies in yeast meiosis.
Michael Knop (1), Martin Finkbeiner (1), Simone Reber (2), Peter Maier (1)
(1) Cell Biology, EMBL, Meyerhofstr. 1, Heidelberg, 69117, Germany ; (2) Institute of Biochemistry, ETH Hoenggerberg, CH-8093 Zuerich, Switzerland
Hijacking a viral A/B toxin on its way through the yeast cell.
Manfred J. Schmitt
Microbiology (FR 8.3), Applied Molecular Biology, Im Stadtwald, Saarbrücken, D-66041, Germany
| Plenary Session 6 - Compartmenting the Cell |
Cargo protein sorting upon exit from the endoplasmic reticulum.
Pierre Morsomme (1), Cristina Prescianotto-Baschong (2), Howard Riezman (3)
(1) Unité de Biochimie Physiologique, Institut des Sciences de la Vie, Université catholique de Louvain, 2/20 Place Croix du Sud, B-1348 Louvain-la-Neuve, Belgium; (2) Biozentrum of the University of Basel, Klingelbergstrasse 70, CH-4056 Basel; (3) Biochemistry, University of Geneva, 30, quai E. Ansermet, Geneva, CH-1211, Switzerland
Yeast vacuoles as a model to study the mechanism of intracellular membrane fusion.
Andreas Mayer
Friedrich-Miescher-Labor, Max-Planck-Gesellschaft, Spemannstr. 37-39, Tuebingen, 72076, Germany
The application of systems biology to peroxisome biogenesis and function.
Yuen Yi C. Tam (1), Franco J. Vizeacoumar (1), Juan Carlos Torres-Guzman (1), Jennifer J. Smith (2), Marcello Marelli (2), John D. Aitchison (2), Richard A. Rachubinski (1)
(1) Cell Biology, University of Alberta, MSB 5-14, Edmonton, AB T6G 2H7, Canada ; (2) Institute for Systems Biology, Seattle, WA 98103-8904, USA
The retrograde response pathway.
Ronald A. Butow, Zhenghang Liu
Molecular Biology, UT Southwestern Medical Center, 6000 Harry Hines Blv, Dallas, TX 75390, USA
| Plenary Session 7 - Controlling Transcriptome and Proteome |
Contending with obstacles to RNA polymerase II transcription: nucleosomes and DNA damage.
Arnold Kristjuhan, James Reid, Jesper Q Svejstrup
Clare Hall Laboratories, Cancer Research UK, Blanche Lane, South Mimms, EN6 3LD, UK
Amino Acid Control of Metabolism and Differentiation
Gerhard H. Braus
Institute of Microbiology & Genetics, Georg-August University, D-37077 Göttingen, Germany,
Mechanism of mRNA export and coupling to transcription.
Ed Hurt, Tamás Fischer, Attila Rácz, Susana Rodriguez-Navarro, Marisa Oppizzi, Katja Strässer
Biochemie-Zentrum Heidelberg, Im Neuenheimer Feld 328, D-69120 Heidelberg, Germany
The proteasome and its associated proteins.
Daniel Finley, David Leggett, Suzanne Elsasser, John Hanna, Bernat Crossas
Cell Biology, Harvard Medical School, 240 Longwood Ave, Boston, MA 02115, USA
| Plenary Session 8 - The Dynamics of Cellular Signalling |
Osmotic stress signaling: a complex path from the plasma membrane to the nucleus.
Gustav Ammerer
Biochemistry and Mol Cell Biol, Univ. Vienna, Dr. Bohrgasse 9, Vienna, A1030, Austria
Sensing extracellular amino acids - novel Ying and Yang mechanisms control SPS sensor initiated signals.
Per Ljungdahl, Claes Andréasson, Arezou Zargari, Mirta Boban
Ludwig Inst. Cancer Research, Stockholm Branch, Nobels väg 3, Stockholm, SE-17177, Sweden
Nutrient-sensing systems for control of protein kinase A dependent signalling.
Johan M. Thevelein, Ruud Gelade, Frank Giots, Inge Holsbeeks, Ole Lagatie, Katleen Lemaire, Sam Van de Velde, Patrick Van Dijck
Lab. Mol. Cell Biol., K.U.Leuven, Kasteelp. Arenberg31, Leuven-Heverlee, B-3001, Belgium
Regulation of the Snf1 kinase.
Marian Carlson, Seung-Pyo Hong, Kristina Hedbacker
Genetics and Development, Columbia University, 701 W. 168th St., New York, NY 10032, USA
| Plenary Session 9 - Towards Understanding the Whole Cell |
Quantitative Analysis of Signaling.
Erin OShea, Melissa Thomas, Mike Springer, Dennis Wykoff, Felix Lam
Biochemistry & Biophysics, UC-San Francisco, 600 16th Street, San Francisco, CA 94143-2240, USA
Systems biology of glucose repression in S. cerevisiae.
Jens Nielsen
Center for Process Biotech, Technical University of Denmar, Building 223, Lyngby, DK-2800, Denmark
The Alpha Project and the Dream of a Predictive Biology.
Roger Brent
Research, Molecular Sciences Institute, 2168 Shattuck 2nd Fl, Berkeley, CA 94704, USA