SEC20/YDR498C Single Page Format

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This page provides an alternative format to the SGD Locus Summary Page. Note that additional information may be available on or linked from the standard format SGD Locus Summary page.

Contents

SGD Locus Page

Names and Identifiers [TOP] [NEXT] Help
Standard Name Systematic Name Alias Feature Type SGDID
SEC20 YDR498C   ORF, Verified S000002906
Description
Membrane glycoprotein v-SNARE involved in retrograde transport from the Golgi to the ER; required for N- and O-glycosylation in the Golgi but not in the ER; interacts with the Dsl1p complex through Tip20p

GO Annotations [TOP] [NEXT] Help
Molecular Function
Annotation(s)Reference(s)EvidenceAssigned By
SNAP receptor activityPelham HR (1999) SNAREs and the secretory pathway-lessons from yeast. Exp Cell Res 247(1):1-8
SGD Papers Entry  Pubmed Entry  Reference LINKOUT  
TAS : Traceable Author Statement
Assigned on 2001-01-18
SGD
Biological Process
Annotation(s)Reference(s)EvidenceAssigned By
ER-dependent peroxisome organizationPerry RJ, et al. (2009) Endoplasmic Reticulum-Associated Secretory Proteins Sec20p, Sec39p, and Dsl1p Are Involved in Peroxisome Biogenesis. Eukaryot Cell 8(6):830-843
SGD Papers Entry  Pubmed Entry  Reference LINKOUT  
IMP : Inferred from Mutant Phenotype
Assigned on 2009-05-15
SGD
protein transportGOA curators (2000) Gene Ontology annotation based on Swiss-Prot keyword mapping.
SGD Papers Entry  Reference full text  
IEA : Inferred from Electronic Annotation with EBI:KW-0653
Assigned on 2007-05-23
UniProtKB
retrograde vesicle-mediated transport, Golgi to ERPelham HR (1999) SNAREs and the secretory pathway-lessons from yeast. Exp Cell Res 247(1):1-8
SGD Papers Entry  Pubmed Entry  Reference LINKOUT  
TAS : Traceable Author Statement
Assigned on 2001-01-18
SGD
translational elongationHuttenhower C and Troyanskaya OG (2009) Prediction of Gene Ontology annotations by integrating high-throughput datasets
SGD Papers Entry  
RCA : Reviewed Computational Analysis
Assigned on 2009-08-06
bioPIXIE_MEFIT
transportGOA curators (2000) Gene Ontology annotation based on Swiss-Prot keyword mapping.
SGD Papers Entry  Reference full text  
IEA : Inferred from Electronic Annotation with EBI:KW-0813
Assigned on 2007-05-23
UniProtKB
vesicle fusionPelham HR (1999) SNAREs and the secretory pathway-lessons from yeast. Exp Cell Res 247(1):1-8
SGD Papers Entry  Pubmed Entry  Reference LINKOUT  
TAS : Traceable Author Statement
Assigned on 2001-01-18
SGD
vesicle-mediated transportGOA curators (2000) Gene Ontology annotation based on Swiss-Prot keyword mapping.
SGD Papers Entry  Reference full text  
IEA : Inferred from Electronic Annotation with EBI:KW-0931
Assigned on 2008-02-14
UniProtKB
Cellular Component
Annotation(s)Reference(s)EvidenceAssigned By
endoplasmic reticulumKumar A, et al. (2002) Subcellular localization of the yeast proteome. Genes Dev 16(6):707-19
SGD Papers Entry  Pubmed Entry  Reference LINKOUT  Web Supplement  Web Supplement  yfgdb  
IDA : Inferred from Direct Assay
Assigned on 2002-05-07
SGD
GOA curators (2000) Gene Ontology annotation based on Swiss-Prot keyword mapping.
SGD Papers Entry  Reference full text  
IEA : Inferred from Electronic Annotation with EBI:KW-0256
Assigned on 2009-10-01
UniProtKB
endoplasmic reticulum membranePelham HR (1999) SNAREs and the secretory pathway-lessons from yeast. Exp Cell Res 247(1):1-8
SGD Papers Entry  Pubmed Entry  Reference LINKOUT  
TAS : Traceable Author Statement
Assigned on 2001-01-18
SGD
integral to membraneGOA curators (2000) Gene Ontology annotation based on Swiss-Prot keyword mapping.
SGD Papers Entry  Reference full text  
IEA : Inferred from Electronic Annotation with EBI:KW-0812
Assigned on 2007-05-23
UniProtKB
GOA curators and UniProt curators (2007) Gene Ontology annotation based on Swiss-Prot Subcellular Location vocabulary mapping.
SGD Papers Entry  Reference full text  
IEA : Inferred from Electronic Annotation with EBI:SL-9908
Assigned on 2009-10-01
UniProtKB
membraneGOA curators (2000) Gene Ontology annotation based on Swiss-Prot keyword mapping.
SGD Papers Entry  Reference full text  
IEA : Inferred from Electronic Annotation with EBI:KW-0472
Assigned on 2007-05-23
UniProtKB
colocalizes_with peroxisomePerry RJ, et al. (2009) Endoplasmic Reticulum-Associated Secretory Proteins Sec20p, Sec39p, and Dsl1p Are Involved in Peroxisome Biogenesis. Eukaryot Cell 8(6):830-843
SGD Papers Entry  Pubmed Entry  Reference LINKOUT  
IDA : Inferred from Direct Assay
Assigned on 2009-05-15
SGD

Pathways [TOP] [NEXT] Help
No pathways available

Summary Paragraph [TOP] [NEXT] Help
No summary paragraph available

Basic References [TOP]   Help
BASIC INFORMATION REFERENCES forSEC20/YDR498C for SEC20
1)Pelham HR (1999) SNAREs and the secretory pathway-lessons from yeast. Exp Cell Res 247(1):1-8
SGD Papers Entry  Pubmed Entry  Reference LINKOUT  
2)Schleip I, et al. (2001) The yeast SEC20 gene is required for N- and O-glycosylation in the Golgi. Evidence that impaired glycosylation does not correlate with the secretory defect. J Biol Chem 276(31):28751-8
SGD Papers Entry  Pubmed Entry  Reference LINKOUT  
3)Tripathi A, et al. (2009) Structural characterization of Tip20p and Dsl1p, subunits of the Dsl1p vesicle tethering complex. Nat Struct Mol Biol 16(2):114-23
SGD Papers Entry  Pubmed Entry  Reference LINKOUT  
4)Novick P and Schekman R (1979) Secretion and cell-surface growth are blocked in a temperature-sensitive mutant of Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 76(4):1858-62
SGD Papers Entry  Pubmed Entry  
5)Novick P, et al. (1980) Identification of 23 complementation groups required for post-translational events in the yeast secretory pathway. Cell 21(1):205-15
SGD Papers Entry  Pubmed Entry  Reference LINKOUT  

Mutant Phenotypes [TOP] [NEXT] Help
Phenotype page for SEC20/YDR498C

Interactions: genetic, physical, and other gene-gene links. [TOP] [NEXT] Help
Interaction page for SEC20/YDR498C

Homologs [TOP] [NEXT] Help
  • Comparison Resources
  • Physical Properties and Transcript Information: predicted from sequence [TOP] [NEXT] Help
    Protein Sequence Calculations
    from Predicted Full length Translation
    N-term MVVTFLQ
    C-term IVSHDEL
    Length(aa) 383
    MW(Da) 43,882
    pI 5.92
    Amino Acid Composition (full length)
    GCG tools: PepPlot, Helical Wheel, PepStruct

    Transcript Translation Calculations
    Codon Bias 0.043  
    Codon Adaptation Index 0.140  
    Frequency of Optimal Codons 0.432  
    Hydropathicity of Protein -0.300  
    Aromaticity Score 0.084  

                              10        20        30        40        50
                               |         |         |         |         |
                      MVVTFLQDLEVLQDALLNNLQKLSAISRRKESGESKHDNKDSFAAIANEH
                      NDEEEEIEFEDLVNIIESKVSDFESVLKCSIVEMTYKYPELKLQWEKSPR
                      YDQCDKLHIVKLDKQMNEDIYAQLVEELDFVLQFVDWFYCYRLKVKEILR
                      QHHKRDLAWNDEKRDRAIKFHAVDYDKLHQGTSSSSSLTSTSMEKASTRE
                      KLLSKTKQLTNNLVRGNQILQSGILQSDLNLDELRAQTNSLTQIDDKYTQ
                      FETVFKKTADLVKVLENASHQEKRDVYLSLGFLLCCVSWVLWRRIFKLPV
                      KLGLWLLFKFFKGILVTLGLVKSYAGSSSSLQAPSLVLNAPILATTTTSS
                      ATSVEPFASVSAVSSIQRAVDEAVDRIVSHDEL*
    

    Protein Structures from PDB: proteins of known structure with sequence similarity to SEC20/YDR498C, based on Smith-Waterman analysis. [TOP] [NEXT] Help
    No protein structure information available.

    Genome-wide Expression and Other Large-Scale Analyses [TOP] [NEXT] Help
  • Functional Analysis
  • You can also search multiple datasets simultaneously using Expression Connection for expression studies or Function Junction for other large scale analyses.

    Locus History (misc. notes) [TOP] [NEXT] Help
    Nomenclature History
    Standard NameReference
    SEC20Novick P, et al. (1980) Identification of 23 complementation groups required for post-translational events in the yeast secretory pathway. Cell 21(1):205-15
    SGD Papers Entry  Pubmed Entry  Reference LINKOUT  

    Sequence Retrieval [TOP] [NEXT] Help
    Sequence Type Output Format
    Genomic DNA GCG | FASTA | NoHeader
    Genomic DNA with 1 kb up and downstream GCG | FASTA | NoHeader
    DNA coding sequence
    (without introns, without flanking regions)
    GCG | FASTA | NoHeader
    Protein Translation of ORF GCG | FASTA | NoHeader
    6-Frame Translation(with Restriction Map) GCG
    Restriction Fragment Sizes GCG
  • Sequence Analysis Tools
  • Sequence from other databases
    Sequence IDSource
    YDR498CSGD Systematic Sequence
    852109NCBI: Gene ID
    NP_010786.1NCBI: RefSeq protein version ID
    NP_010786.1NCBI: RefSeq protein version ID
    6320706NCBI: NCBI protein GI

    Map and Displays [TOP] [NEXT] Help
    Physical, Genetic Maps: Chromosomal Feature Map GBrowse Combined Physical and Genetic Map Genetic Distance vs. Physical Distance Ratios
    Similarity Viewers: Synteny Viewer Genomic Stripe View SAGE Results Map  

    Localization [TOP] [NEXT] Help
  • Localization Resources
  • Community Annotation [TOP] [NEXT] Help
    No community annotation available.

    Literature Guide: papers categorized by topic. [TOP]   Help
    TopicsReferenceOther Genes Addressed
    44 curated references; 0 references not yet curated
    Reviews
    Nagotu S, et al. (2010) Divide et impera: the dictum of peroxisomes. Traffic 11(2):175-84
    SGD Papers Entry  Pubmed Entry  Reference LINKOUT  
    |ARF1 |ARF3 |CAF4 |DNM1 |DSL1 |EMP24 |FIS1 |MDV1 |PEX11 |PEX2 |PEX3 |PEX30 |PEX31 |SEC39 |MORE
    Cellular Location
    Function/Process
    Mutants/Phenotypes
    Protein Processing/Modification/Regulation
    Strains/Constructs
    Perry RJ, et al. (2009) Endoplasmic Reticulum-Associated Secretory Proteins Sec20p, Sec39p, and Dsl1p Are Involved in Peroxisome Biogenesis. Eukaryot Cell 8(6):830-843
    SGD Papers Entry  Pubmed Entry  Reference LINKOUT  
    |BOS1 |COP1 |DSL1 |PEX3 |POT1 |SEC1 |SEC11 |SEC12 |SEC13 |SEC14 |SEC17 |SEC18 |SEC21 |SEC26 |MORE
    Protein Sequence Features
    Protein-protein Interactions
    Ren Y, et al. (2009) A structure-based mechanism for vesicle capture by the multisubunit tethering complex Dsl1. Cell 139(6):1119-29
    SGD Papers Entry  Pubmed Entry  Reference LINKOUT  SGD Curated Comments & Errata
    |DSL1 |EXO70 |SEC17 |SEC22 |SEC39 |TIP20 |UFE1 |USE1
    Reviews
    Saito C and Ueda T (2009) Chapter 4 Functions of RAB and SNARE Proteins in Plant Life. Int Rev Cell Mol Biol 274:183-233
    SGD Papers Entry  Pubmed Entry  Reference LINKOUT  
    |MSO1 |PEP12 |PEP3 |PEP5 |PEP7 |SAR1 |SEC1 |SEC2 |SEC4 |SEC9 |SFT1 |SNC1 |SSO1 |USE1 |MORE
    Reviews
    Schmitt HD and Jahn R (2009) A tethering complex recruits SNAREs and grabs vesicles. Cell 139(6):1053-5
    SGD Papers Entry  Pubmed Entry  Reference LINKOUT  
    |BET3 |BET5 |DSL1 |GSG1 |SEC1 |SEC23 |SEC39 |TIP20 |TRS20 |TRS23 |TRS31 |TRS33 |USE1
    Mutants/Phenotypes
    Strains/Constructs
    Singh J and Tyers M (2009) A Rab escort protein integrates the secretion system with TOR signaling and ribosome biogenesis. Genes Dev 23(16):1944-58
    SGD Papers Entry  Pubmed Entry  Reference LINKOUT  
    |AKR1 |AVL9 |DPM1 |ERG5 |ERV29 |GAB1 |GPI16 |MRS6 |MSB4 |MSN5 |PKC1 |ROT1 |SEC17 |SEC23 |MORE
    Genetic Interactions
    Mutants/Phenotypes
    Protein-protein Interactions
    Strains/Constructs
    Tripathi A, et al. (2009) Structural characterization of Tip20p and Dsl1p, subunits of the Dsl1p vesicle tethering complex. Nat Struct Mol Biol 16(2):114-23
    SGD Papers Entry  Pubmed Entry  Reference LINKOUT  
    |DSL1 |EXO70 |EXO84 |SEC15 |SEC39 |SEC6 |TIP20 |USE1
    Mutants/Phenotypes
    Strains/Constructs
    Ungar L, et al. (2009) A genome-wide screen for essential yeast genes that affect telomere length maintenance. Nucleic Acids Res 37(12):3840-9
    SGD Papers Entry  Pubmed Entry  Reference LINKOUT  
    |AAR2 |ALA1 |APC4 |ARC15 |ARC35 |ARP2 |ARP3 |BBP1 |CBF5 |CDC13 |CDC16 |CDC19 |CDC34 |CDC36 |MORE
    Mutants/Phenotypes
    Strains/Constructs
    Breslow DK, et al. (2008) A comprehensive strategy enabling high-resolution functional analysis of the yeast genome. Nat Methods 5(8):711-8
    SGD Papers Entry  Pubmed Entry  Reference LINKOUT  
    |AAR2 |ABD1 |ABF1 |ACC1 |ACP1 |ADE13 |AFG2 |ALA1 |ALG1 |ALG13 |ALG14 |ALG2 |ALG7 |ALR1 |MORE
    Genetic Interactions
    Higashio H, et al. (2008) Smy2p Participates in COPII Vesicle Formation Through the Interaction with Sec23p/Sec24p Subcomplex. Traffic 9(1):79-93
    SGD Papers Entry  Pubmed Entry  Reference LINKOUT  Reference LINKOUT  
    |BET1 |COG2 |COG3 |RET1 |RET3 |SAR1 |SEC12 |SEC13 |SEC16 |SEC17 |SEC18 |SEC21 |SEC22 |SEC23 |MORE
    Evolution
    Fungal Related Genes/Proteins
    Non-Fungal Related Genes/Proteins
    Koumandou VL, et al. (2007) Control systems for membrane fusion in the ancestral eukaryote; evolution of tethering complexes and SM proteins. BMC Evol Biol 7():29
    SGD Papers Entry  Pubmed Entry  Reference LINKOUT  Reference LINKOUT  Reference LINKOUT  
    |BET3 |BET5 |COG1 |COG2 |COG3 |COG4 |COG5 |COG6 |COG7 |COG8 |DSL1 |EXO70 |EXO84 |GSG1 |MORE
    Fungal Related Genes/Proteins
    Kuratsu M, et al. (2007) Systematic analysis of SNARE localization in the filamentous fungus Aspergillus oryzae. Fungal Genet Biol 44(12):1310-23
    SGD Papers Entry  Pubmed Entry  Reference LINKOUT  
    |BET1 |BOS1 |GOS1 |NYV1 |PEP12 |SEC22 |SEC9 |SED5 |SFT1 |SNC1 |SNC2 |SPO20 |SSO1 |SSO2 |MORE
    Function/Process
    Mutants/Phenotypes
    Strains/Constructs
    Altmann K and Westermann B (2005) Role of essential genes in mitochondrial morphogenesis in Saccharomyces cerevisiae. Mol Biol Cell 16(11):5410-7
    SGD Papers Entry  Pubmed Entry  Reference LINKOUT  Web Supplement  yfgdb  
    |ARC35 |ARC40 |ARP2 |BFR2 |CCT4 |CCT6 |CDC34 |CDC53 |COF1 |DSL1 |ERG1 |ERG10 |ERG12 |ERG13 |MORE
    Reviews
    Hong W (2005) SNAREs and traffic. Biochim Biophys Acta 1744(2):120-44
    SGD Papers Entry  Pubmed Entry  Reference LINKOUT  
    |BET1 |BOS1 |GOS1 |NYV1 |PEP12 |SEC22 |SEC9 |SED5 |SFT1 |SNC1 |SNC2 |SPO20 |SSO1 |SSO2 |MORE
    Cellular Location
    Protein-protein Interactions
    Kraynack BA, et al. (2005) Dsl1p, Tip20p, and the novel Dsl3(Sec39) protein are required for the stability of the Q/t-SNARE complex at the endoplasmic reticulum in yeast. Mol Biol Cell 16(9):3963-77
    SGD Papers Entry  Pubmed Entry  Reference LINKOUT  
    |DSL1 |SEC39 |TIP20 |UFE1 |USE1
    Genetic Interactions
    Mutants/Phenotypes
    Protein-protein Interactions
    Strains/Constructs
    Li Y, et al. (2005) Structure-based functional analysis reveals a role for the SM protein Sly1p in retrograde transport to the endoplasmic reticulum. Mol Biol Cell 16(9):3951-62
    SGD Papers Entry  Pubmed Entry  Reference LINKOUT  
    |BOS1 |DSL1 |SEC22 |SLY1 |TIP20 |UFE1 |USE1
    Genetic Interactions
    Mutants/Phenotypes
    Strains/Constructs
    Routt SM, et al. (2005) Nonclassical PITPs activate PLD via the Stt4p PtdIns-4-kinase and modulate function of late stages of exocytosis in vegetative yeast. Traffic 6(12):1157-72
    SGD Papers Entry  Pubmed Entry  Reference LINKOUT  Reference LINKOUT  Reference LINKOUT  
    |CSR1 |LSB6 |MSS4 |PDR16 |PDR17 |PIK1 |PSD1 |SAC1 |SEC1 |SEC10 |SEC12 |SEC13 |SEC14 |SEC15 |MORE
    Cellular Location
    Function/Process
    Fungal Related Genes/Proteins
    Protein Sequence Features
    Reviews
    Burri L and Lithgow T (2004) A complete set of SNAREs in yeast. Traffic 5(1):45-52
    SGD Papers Entry  Pubmed Entry  Reference LINKOUT  
    |BET1 |BOS1 |FRT1 |FRT2 |GOS1 |NYV1 |PEP12 |SEC22 |SEC9 |SED5 |SFT1 |SNC1 |SNC2 |SSO1 |MORE
    Non-Fungal Related Genes/Proteins
    Nakajima K, et al. (2004) Involvement of BNIP1 in apoptosis and endoplasmic reticulum membrane fusion. EMBO J 23(16):3216-26
    SGD Papers Entry  Pubmed Entry  Reference LINKOUT  Reference LINKOUT  

    Function/Process
    Protein Sequence Features
    Protein-protein Interactions
    Burri L, et al. (2003) A SNARE required for retrograde transport to the endoplasmic reticulum. Proc Natl Acad Sci U S A 100(17):9873-7
    SGD Papers Entry  Pubmed Entry  
    |SEC22 |UFE1 |USE1 |YKT6
    Function/Process
    Genetic Interactions
    Mutants/Phenotypes
    Protein-protein Interactions
    Strains/Constructs
    Dilcher M, et al. (2003) Use1p is a yeast SNARE protein required for retrograde traffic to the ER. EMBO J 22(14):3664-74
    SGD Papers Entry  Pubmed Entry  
    |BET1 |BOS1 |SEC22 |SED5 |UFE1 |USE1
    Fungal Related Genes/Proteins
    Weber Y, et al. (2002) Sec20p-interacting proteins (Tip20p, Ufe1p) in the retrograde secretory pathway of the fungal pathogen Candida albicans. Mol Genet Genomics 268(4):468-76
    SGD Papers Entry  Pubmed Entry  Reference LINKOUT  
    |TIP20 |UFE1
    Cellular Location
    Function/Process
    Genetic Interactions
    Andag U, et al. (2001) The coatomer-interacting protein Dsl1p is required for Golgi-to-endoplasmic reticulum retrieval in yeast. J Biol Chem 276(42):39150-60
    SGD Papers Entry  Pubmed Entry  Reference LINKOUT  
    |COP1 |DSL1 |ERD2 |KAR2 |SEC22 |TIP20
    Cellular Location
    Function/Process
    Protein Physical Properties
    Protein-protein Interactions
    Reilly BA, et al. (2001) Golgi-to-endoplasmic reticulum (ER) retrograde traffic in yeast requires Dsl1p, a component of the ER target site that interacts with a COPI coat subunit. Mol Biol Cell 12(12):3783-96
    SGD Papers Entry  Pubmed Entry  Reference LINKOUT  
    |DSL1 |KAR2 |RET2 |SLY1 |TIP20 |UFE1
    Function/Process
    Mutants/Phenotypes
    Strains/Constructs
    Schleip I, et al. (2001) The yeast SEC20 gene is required for N- and O-glycosylation in the Golgi. Evidence that impaired glycosylation does not correlate with the secretory defect. J Biol Chem 276(31):28751-8
    SGD Papers Entry  Pubmed Entry  Reference LINKOUT  

    Fungal Related Genes/Proteins
    Protein Sequence Features
    Weber Y, et al. (2001) Divergence of eukaryotic secretory components: the Candida albicans homolog of the Saccharomyces cerevisiae ++Sec20 protein is N terminally truncated, and its levels determine antifungal drug resistance and growth. J Bacteriol 183(1):46-54
    SGD Papers Entry  Pubmed Entry  Reference LINKOUT  
    |TIP20
    Function/Process
    Genetic Interactions
    Mutants/Phenotypes
    Strains/Constructs
    Finger FP and Novick P (2000) Synthetic interactions of the post-Golgi sec mutations of Saccharomyces cerevisiae. Genetics 156(3):943-51
    SGD Papers Entry  Pubmed Entry  Reference LINKOUT  
    |ACT1 |CDC12 |CDC24 |CDC28 |CDC42 |DSS4 |GDI1 |MYO2 |SEC1 |SEC10 |SEC12 |SEC13 |SEC14 |SEC15 |MORE
    Reviews
    Pelham HR (1999) SNAREs and the secretory pathway-lessons from yeast. Exp Cell Res 247(1):1-8
    SGD Papers Entry  Pubmed Entry  Reference LINKOUT  
    |GOS1 |NYV1 |SEC22 |SEC9 |SED5 |SNC1 |SNC2 |SPO20 |SSO1 |SSO2 |TLG1 |TLG2 |UFE1 |VAM3 |MORE
    Function/Process
    Genetic Interactions
    Mutants/Phenotypes
    Strains/Constructs
    Substrates/Ligands/Cofactors
    Ballensiefen W, et al. (1998) Recycling of the yeast v-SNARE Sec22p involves COPI-proteins and the ER transmembrane proteins Ufe1p and Sec20p. J Cell Sci 111 ( Pt 11):1507-20
    SGD Papers Entry  Pubmed Entry  Reference LINKOUT  
    |SEC21 |SEC22 |SEC27 |UFE1
    Cellular Location
    Function/Process
    Genetic Interactions
    Mutants/Phenotypes
    Protein-protein Interactions
    Strains/Constructs
    Frigerio G (1998) The Saccharomyces cerevisiae early secretion mutant tip20 is synthetic lethal with mutants in yeast coatomer and the SNARE proteins Sec22p and Ufe1p. Yeast 14(7):633-46
    SGD Papers Entry  Pubmed Entry  Reference LINKOUT  
    |RET2 |SEC21 |SEC22 |SEC27 |TIP20 |UFE1
    Mutants/Phenotypes
    Protein-protein Interactions
    Strains/Constructs
    Patel SK, et al. (1998) Organelle membrane fusion: a novel function for the syntaxin homolog Ufe1p in ER membrane fusion. Cell 92(5):611-20
    SGD Papers Entry  Pubmed Entry  Reference LINKOUT  
    |CDC48 |TIP20 |UFE1
    Function/Process
    Protein-protein Interactions
    Cosson P, et al. (1997) The Sec20/Tip20p complex is involved in ER retrieval of dilysine-tagged proteins. Eur J Cell Biol 73(2):93-7
    SGD Papers Entry  Pubmed Entry  
    |EMP47 |TIP20
    Cellular Location
    Function/Process
    Genetic Interactions
    Mutants/Phenotypes
    Lewis MJ, et al. (1997) A novel SNARE complex implicated in vesicle fusion with the endoplasmic reticulum. EMBO J 16(11):3017-24
    SGD Papers Entry  Pubmed Entry  Reference LINKOUT  
    |SEC22 |TIP20 |UFE1
    Function/Process
    Mutants/Phenotypes
    Strains/Constructs
    Shimma Y, et al. (1997) A defect in GTP synthesis affects mannose outer chain elongation in Saccharomyces cerevisiae. Mol Gen Genet 256(5):469-80
    SGD Papers Entry  Pubmed Entry  
    |ALG1 |GUK1 |PSA1
    Protein-protein Interactions
    Voet M, et al. (1997) The sequence of a nearly unclonable 22.8 kb segment on the left arm chromosome VII from Saccharomyces cerevisiae reveals ARO2, RPL9A, TIP1, MRF1 genes and six new open reading frames. Yeast 13(2):177-82
    SGD Papers Entry  Pubmed Entry  Reference LINKOUT  
    |ARO2 |FLC3 |GPI10 |HUL5 |MRF1 |ROG1 |RPL9A |RRT6 |TIP20 |YGL140C
    Mutants/Phenotypes
    Regulatory Role
    Lewis MJ and Pelham HR (1996) SNARE-mediated retrograde traffic from the Golgi complex to the endoplasmic reticulum. Cell 85(2):205-15
    SGD Papers Entry  Pubmed Entry  Reference LINKOUT  
    |ERD2 |SEC21 |UFE1
    Function/Process
    Genetic Interactions
    Protein-protein Interactions
    Regulatory Role
    Sweet DJ and Pelham HR (1993) The TIP1 gene of Saccharomyces cerevisiae encodes an 80 kDa cytoplasmic protein that interacts with the cytoplasmic domain of Sec20p. EMBO J 12(7):2831-40
    SGD Papers Entry  Pubmed Entry  
    |TIP20
    Reviews
    Pryer NK, et al. (1992) Vesicle-mediated protein sorting. Annu Rev Biochem 61:471-516
    SGD Papers Entry  Pubmed Entry  
    |ARF1 |ARF2 |BET1 |BET2 |BOS1 |CHC1 |CLC1 |ERD1 |ERD2 |SAR1 |SEC1 |SEC12 |SEC13 |SEC14 |MORE
    Cellular Location
    DNA/RNA Sequence Features
    Function/Process
    Protein Processing/Modification/Regulation
    Protein Sequence Features
    Regulatory Role
    Strains/Constructs
    Sweet DJ and Pelham HR (1992) The Saccharomyces cerevisiae SEC20 gene encodes a membrane glycoprotein which is sorted by the HDEL retrieval system. EMBO J 11(2):423-32
    SGD Papers Entry  Pubmed Entry  

    Function/Process
    Mutants/Phenotypes
    Puoti A, et al. (1991) Biosynthesis of mannosylinositolphosphoceramide in Saccharomyces cerevisiae is dependent on genes controlling the flow of secretory vesicles from the endoplasmic reticulum to the Golgi. J Cell Biol 113(3):515-25
    SGD Papers Entry  Pubmed Entry  Reference LINKOUT  
    |SEC12 |SEC13 |SEC14 |SEC16 |SEC17 |SEC18 |SEC21 |SEC22 |SEC23 |SEC6 |SEC7
    Reviews
    Newman AP and Ferro-Novick S (1990) Defining components required for transport from the ER to the Golgi complex in yeast. Bioessays 12(10):485-91
    SGD Papers Entry  Pubmed Entry  
    |ARF1 |ARF2 |BET1 |BET2 |BOS1 |SAR1 |SEC12 |SEC13 |SEC16 |SEC17 |SEC18 |SEC21 |SEC22 |SEC23 |MORE
    Function/Process
    Mutants/Phenotypes
    Strains/Constructs
    Ramirez RM, et al. (1983) Plasma membrane expansion terminates in Saccharomyces cerevisiae secretion-defective mutants while phospholipid synthesis continues. J Bacteriol 154(3):1276-83
    SGD Papers Entry  Pubmed Entry  
    |GDI1 |SEC1 |SEC10 |SEC11 |SEC12 |SEC13 |SEC14 |SEC15 |SEC16 |SEC17 |SEC18 |SEC2 |SEC21 |SEC22 |MORE
    Function/Process
    Genetic Interactions
    Mutants/Phenotypes
    Strains/Constructs
    Novick P, et al. (1981) Order of events in the yeast secretory pathway. Cell 25(2):461-9
    SGD Papers Entry  Pubmed Entry  Reference LINKOUT  
    |GDI1 |SEC1 |SEC12 |SEC14 |SEC15 |SEC16 |SEC18 |SEC2 |SEC21 |SEC22 |SEC23 |SEC3 |SEC4 |SEC5 |MORE
    Function/Process
    Genetic Interactions
    Mutants/Phenotypes
    Strains/Constructs
    Novick P, et al. (1980) Identification of 23 complementation groups required for post-translational events in the yeast secretory pathway. Cell 21(1):205-15
    SGD Papers Entry  Pubmed Entry  Reference LINKOUT  
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