Castelnuovo M and Stutz F (2013) Gene loops and HDACs to promote transcription directionality. Nucleus 4(2):92-4
Abstract: Gene loops have been described in different organisms from yeast to human and form through interaction between components of the transcription pre-initiation complex and Ssu72, a member of the 3' end cleavage and polyadenylation complex. A recent study by Tan-Wong et al. reports a new role for gene loops in promoting ORF transcription directionality from otherwise bidirectional promoters.
|Status: Published||Type: Journal Article||PubMed ID: 23514951|
Topics addressed in this paper
Number of different genes curated to this paper: 3
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