Wickner RB, et al. (2013) Viruses and prions of Saccharomyces cerevisiae. Adv Virus Res 86():1-36
Abstract: Saccharomyces cerevisiae has been a key experimental organism for the study of infectious diseases, including dsRNA viruses, ssRNA viruses, and prions. Studies of the mechanisms of virus and prion replication, virus structure, and structure of the amyloid filaments that are the basis of yeast prions have been at the forefront of such studies in these classes of infectious entities. Yeast has been particularly useful in defining the interactions of the infectious elements with cellular components: chromosomally encoded proteins necessary for blocking the propagation of the viruses and prions, and proteins involved in the expression of viral components. Here, we emphasize the L-A dsRNA virus and its killer-toxin-encoding satellites, the 20S and 23S ssRNA naked viruses, and the several infectious proteins (prions) of yeast.
|Status: Published||Type: Journal Article | Research Support, N.I.H., Intramural | Research Support, Non-U.S. Gov't||PubMed ID: 23498901|
Topics addressed in this paper
Number of different genes curated to this paper: 21
- To go to the Locus page for a gene, click on the gene name.
|Topics||Genes (#21 )|