Mathiasen DP, et al. (2013) Physical mapping and cloning of RAD56. Gene 519(1):182-6
Abstract: Here we report the physical mapping of the rad56-1 mutation to the NAT3 gene, which encodes the catalytic subunit of the NatB N-terminal acetyltransferase in Saccharomyces cerevisiae. Mutation of RAD56 causes sensitivity to X-rays, methyl methanesulfonate, zeocin, camptothecin and hydroxyurea, but not to UV light, suggesting that N-terminal acetylation of specific DNA repair proteins is important for efficient DNA repair.
|Status: Published||Type: Journal Article | Research Support, Non-U.S. Gov't||PubMed ID: 23403232|
Topics addressed in this paper
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