Wang YC and Distefano MD (2012) Solid-phase synthesis of C-terminal peptide libraries for studying the specificity of enzymatic protein prenylation. Chem Commun (Camb) 48(66):8228-30
Abstract: Prenylation is an essential post-translational modification in all eukaryotes. Here we describe the synthesis of a 340-member library of peptides containing free C-termini on cellulose membranes. The resulting library was then used to probe the specificity of protein farnesyltransferase from S. cerevisiae.
|Status: Published||Type: Journal Article||PubMed ID: 22783549|
Topics addressed in this paper
Number of different genes curated to this paper: 3
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