Ehrensberger KM and Bird AJ (2011) Hammering out details: regulating metal levels in eukaryotes. Trends Biochem Sci 36(10):524-31
Abstract: The transition metals zinc, iron and copper are common constituents in a wide range of proteins. Although these metals are all essential for life, when present in excess, they are frequently toxic to cell growth and viability. Therefore, all organisms rely on sophisticated mechanisms to maintain optimal levels of each metal. Genes that encode metal transport or storage proteins are often regulated at the transcriptional level in response to changes in metal status. In this review, we focus on what is known about the transcription factors that mediate these metal-dependent changes. Specifically, we highlight recent advances in our understanding of the mechanisms by which these factors sense metal ions.CI - Published by Elsevier Ltd.
|Status: Published||Type: Journal Article | Research Support, Non-U.S. Gov't | Review||PubMed ID: 21840721|
Topics addressed in this paper
Number of different genes curated to this paper: 21
- To find other papers on a gene and topic, click on the colored ball in the appropriate box.
- displays other papers with information about that topic for that gene.
- displays other papers in SGD that are associated with that topic.
The topic is addressed in these papers but does not describe a specific gene or chromosomal feature.
- To go to the Locus page for a gene, click on the gene name.
|Topics||Genes linked to topics (#11 - 20 )|
|Topics||Genes linked to topics (#21 )|