Finley D (2011) Misfolded proteins driven to destruction by Hul5. Nat Cell Biol 13(11):1290-2
Abstract: Misfolded proteins are potentially toxic and are therefore subjected to highly selective degradation by the ubiquitin-proteasome system. The identification of the Hul5 ubiquitin ligase as a major mediator of such 'quality-control' ubiquitylation following heat shock raises new questions about the design of these pathways.FAU - Finley, Danie.
|Status: Published||Type: Comment | News||PubMed ID: 21983564|
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