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Yamanishi M, et al.  (2011) TPS1 terminator increases mRNA and protein yield in a Saccharomyces cerevisiae expression system. Biosci Biotechnol Biochem 75(11):2234-6

Abstract: Both terminators and promoters regulate gene expression. In Saccharomyces cerevisiae, the TPS1 terminator (TPS1t), coupled to a gene encoding a fluorescent protein, produced more transgenic mRNA and protein than did similar constructs containing other terminators, such as CYC1t, TDH3t, and PGK1t. This suggests that TPS1t can be used as a general terminator in the development of metabolically engineered yeast in high-yield systems.

Status: Published Type: Journal Article PubMed ID: 22056446

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CYC1 MFA2 PGK1 TDH3 TPS1 TPS2 TPS3 TSL1
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