SGD Paper 
Page Contents:
Lang GI and Botstein D (2011) A Test of the Coordinated Expression Hypothesis for the Origin and Maintenance of the GAL Cluster in Yeast. PLoS One 6(9):e25290
Abstract: Metabolic gene clusters-functionally related and physically clustered genes-are a common feature of some eukaryotic genomes. Two hypotheses have been advanced to explain the origin and maintenance of metabolic gene clusters: coordinated gene expression and genetic linkage. Here we test the hypothesis that selection for coordinated gene expression underlies the clustering of GAL genes in the yeast genome. We find that, although clustering coordinates the expression of GAL1 and GAL10, disrupting the GAL cluster does not impair fitness, suggesting that other mechanisms, such as genetic linkage, drive the origin and maintenance metabolic gene clusters.
| Status: Published | Type: Journal Article | PubMed ID: 21966486 |
Topics addressed in this paper
Number of different genes curated to this paper: 3
- To find other papers on a gene and topic, click on the colored ball in the appropriate box.
- displays other papers with information about that topic for that gene.
- displays other papers in SGD that are associated with that topic.
The topic is addressed in these papers but does not describe a specific gene or chromosomal feature.
- To go to the Locus page for a gene, click on the gene name.
Page Contents:
