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Garcia-Lopez MC and Navarro F  (2011) RNA polymerase II conserved protein domains as platforms for protein-protein interactions. Transcription 2(4):193-197

Abstract: RNA polymerase II establishes many protein-protein interactions with transcriptional regulators to coordinate gene expression, but little is known about protein domains involved in the contact with them. We use a new approach to look for conserved regions of the RNA pol II of S. cerevisiae located at the surface of the structure of the complex, hypothesizing that they might be involved in the interaction with transcriptional regulators. We defined five different conserved domains and demonstrate that all of them make contact with transcriptional regulators.

Status: Published Type: Journal Article PubMed ID: 21922063

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DST1 MVP1 RET1 RPA135 RPA190 RPB2 RPO21 RPO31 SPO14 SUA7
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