SGD Paper 
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Williams DE, et al. (2011) Padanamides A and B, highly modified linear tetrapeptides produced in culture by a Streptomyces sp. isolated from a marine sediment. Org Lett 13(15):3936-9
Abstract: Two highly modified linear tetrapeptides, padanamides A (1) and B (2), are produced by laboratory cultures of a Streptomyces sp. obtained from a marine sediment. Padanamide B is cytotoxic to Jurkat cells, and a chemical genomics analysis using Saccharomyces cerevisiae deletion mutants suggested that padanamide A inhibits cysteine and methionine biosynthesis or that these amino acids are involved in the yeast's response to the peptide.
| Status: Published | Type: Journal Article | PubMed ID: 21749075 |
Topics addressed in this paper
Number of different genes curated to this paper: 13
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| Topics | Genes linked to topics (#1 - 10 ) | |||||||||
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| AAH1 | CIN4 | CKI1 | GOT1 | MET32 | MTC4 | MTC5 | OPI3 | OPY2 | PEX14 | |
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| Topics | Genes linked to topics (#11 - 13 ) | ||
|---|---|---|---|
| SMY1 | THP2 | YHM2 | |
| Additional Literature | | | |
| Mutants/Phenotypes | | | |
| Strains/Constructs | | | |
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