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Malagon F and Jensen TH (2011) T-body formation precedes virus-like particle maturation in S. cerevisiae. RNA Biol 8(2):184-9
Abstract: T-bodies are localized S. cerevisiae RNPs containing Ty1 retroviral components and speculated to play a role in the assembly of virus-like particles (VLPs). Mapping requirements for T-body formation, we demonstrate that ectopic expression of immature TyA1/Gag (Gag-p49), a structural component of the Ty1 capsid, is sufficient for T-body formation both under normal conditions as well as in a strain background devoid of endogenous Gag. Moreover, T-bodies are readily formed when Ty1 transposition is blocked. Thus, T-bodies represent an early stage in the Ty1 life cycle, preceding VLP maturation.
| Status: Published | Type: Journal Article | PubMed ID: 21358276 |
Topics addressed in this paper
Number of different genes curated to this paper: 32
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| Topics | Genes linked to topics (#1 - 10 ) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| YAR010C | YARCTy1-1 | YBLWTy1-1 | YBRWTy1-2 | YDRCTy1-1 | YDRCTy1-2 | YDRCTy1-3 | YDRWTy1-4 | YDRWTy1-5 | YERCTy1-1 | |
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| Topics | Genes linked to topics (#11 - 20 ) | |||||||||
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| YERCTy1-2 | YGRCTy1-2 | YGRCTy1-3 | YGRWTy1-1 | YHRCTy1-1 | YJRWTy1-1 | YJRWTy1-2 | YLRCTy1-1 | YLRWTy1-2 | YLRWTy1-3 | |
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| Topics | Genes linked to topics (#21 - 30 ) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| YMLWTy1-1 | YMLWTy1-2 | YMRCTy1-3 | YMRCTy1-4 | YNLCTy1-1 | YNLWTy1-2 | YOLWTy1-1 | YORWTy1-2 | YPLWTy1-1 | YPRCTy1-2 | |
| Additional Literature | | | | | | | | | | |
| Other Features | | | | | | | | | | |
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