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Malagon F and Jensen TH  (2011) T-body formation precedes virus-like particle maturation in S. cerevisiae. RNA Biol 8(2):184-9

Abstract: T-bodies are localized S. cerevisiae RNPs containing Ty1 retroviral components and speculated to play a role in the assembly of virus-like particles (VLPs). Mapping requirements for T-body formation, we demonstrate that ectopic expression of immature TyA1/Gag (Gag-p49), a structural component of the Ty1 capsid, is sufficient for T-body formation both under normal conditions as well as in a strain background devoid of endogenous Gag. Moreover, T-bodies are readily formed when Ty1 transposition is blocked. Thus, T-bodies represent an early stage in the Ty1 life cycle, preceding VLP maturation.

Status: Published Type: Journal Article PubMed ID: 21358276

Topics addressed in this paper

Number of different genes curated to this paper: 32

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Topics Genes linked to topics (#1 - 10 )
YAR010C YARCTy1-1 YBLWTy1-1 YBRWTy1-2 YDRCTy1-1 YDRCTy1-2 YDRCTy1-3 YDRWTy1-4 YDRWTy1-5 YERCTy1-1
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Topics Genes linked to topics (#11 - 20 )
YERCTy1-2 YGRCTy1-2 YGRCTy1-3 YGRWTy1-1 YHRCTy1-1 YJRWTy1-1 YJRWTy1-2 YLRCTy1-1 YLRWTy1-2 YLRWTy1-3
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Topics Genes linked to topics (#21 - 30 )
YMLWTy1-1 YMLWTy1-2 YMRCTy1-3 YMRCTy1-4 YNLCTy1-1 YNLWTy1-2 YOLWTy1-1 YORWTy1-2 YPLWTy1-1 YPRCTy1-2
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Topics Genes linked to topics (#31 - 32 )
YPRCTy1-4 YPRWTy1-3
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