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Uluisik I, et al.  (2011) Genome-wide identification of genes that play a role in boron stress response in yeast. Genomics 97(2):106-11

Abstract: Boron is an essential micronutrient for plants and it is either necessary or beneficial for animals. Studies identified only few genes related to boron metabolism thus far and details of how boron is imported into cells and used in cell metabolism are largely unknown. In order to identify genes that play role in boron metabolism, we screened the entire set of yeast haploid deletion mutants and identified 6 mutants that were resistant to toxic levels of boron, and 21 mutants that were highly sensitive to boron treatment. Furthermore, we performed a proteomic approach to identify additional proteins that are significantly up-regulated by boron treatment. Our results revealed many genes and pathways related to boron stress response and suggest a possible link between boron toxicity and translational control.CI - Copyright (c) 2010. Published by Elsevier Inc.

Status: Published Type: Journal Article PubMed ID: 21035538

Topics addressed in this paper

Number of different genes curated to this paper: 38

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ADE13 ADK1 ARP8 BRE5 BRO1 CCS1 CDC19 CHS3 ELP3 ELP6
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ERG4 FBA1 HEF3 HOM6 IKI3 KRS1 NCS2 NCS6 OCH1 PGK1
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PHO85 PRE9 REG1 RPE1 RPL31A RPL5 SAC1 SLA1 SSE1 TDH3
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Topics Genes linked to topics (#31 - 38 )
THR1 TSA1 UBP2 VPS16 YCR016W YGR283C YJL120W YMR310C
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