SGD Paper 
Bell PJ (2004) Yeast differentiation using histone promoter sequences. Lett Appl Microbiol 38(5):388-92
Abstract: AIMS: To evaluate a new platform for yeast differentiation based on histone promoter regions. METHODS AND RESULTS: The histone gene amino acid sequences of a wide phylogenetic range of organisms were aligned, and primers designed that were capable of amplifying the divergent promoters of the H3-H4 and H2a-H2b loci from yeast. Analysis indicated that the promoter regions were variable in length between species and represented rapidly changing sequences flanked by highly conserved sequences. CONCLUSIONS: The histone promoter regions in yeast provide an excellent locus for the rapid and accurate identification of yeast species. SIGNIFICANCE AND IMPACT OF THE STUDY: This study describes an alternative platform to the ribosomal internal transcribed spacer (ITS) sequences for the identification of yeast species.
| Status: Published | Type: Evaluation Studies | Journal Article | PubMed ID: 15059209 |
Topics addressed in this paper
Number of different genes curated to this paper: 8
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